Identification of the Staphylococcus aureus MSCRAMM clumping factor B (ClfB) binding site in the αC-domain of human fibrinogen

Microbiology

Volumn 154, Issue 2, 2008, Pages 550-558

  Walsh, Evelyn J ^a   Miajlovic, Helen ^a   Gorkun, Oleg V ^b   Foster, Timothy J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CLUMPING FACTOR B PROTEIN; FIBRINOGEN; MICROBIAL SURFACE COMPONENT RECOGNIZING ADHESIVE MATRIX MOLECULE; UNCLASSIFIED DRUG;

ALPHA CHAIN; AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM ADHERENCE; BINDING AFFINITY; BINDING SITE; GENE DELETION; HUMAN; LACTOCOCCUS LACTIS; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; STAPHYLOCOCCUS AUREUS; WILD TYPE;

ADHESINS, BACTERIAL; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITES; CLONING, MOLECULAR; FIBRINOGEN; HUMANS; LACTOCOCCUS LACTIS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT PROTEINS; STAPHYLOCOCCUS AUREUS;

LACTOCOCCUS LACTIS; STAPHYLOCOCCUS AUREUS;

EID: 39749134910     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.2007/010868-0     Document Type: Article

References (41)

1. Bolyard, M. G. & Lord, S. T. (1988). High-level expression of a functional human fibrinogen gamma chain in Escherichia coli. Gene 66, 183-192.
2. Burton, R. A., Tsurupa, G., Medved, L. & Tjandra, N. (2006). Identification of an ordered compact structure within the recombinant bovine fibrinogen alphaC-domain fragment by NMR. Biochemistry 45, 2257-2266.
3. Cierniewski, C. S. & Budzynski, A. Z. (1992). Involvement of the alpha-chain in fibrin clot formation. Effect of monoclonal-antibodies. Biochemistry 31, 4248-4253.
4. Cole, A. M., Tahk, S., Oren, A., Yoshioka, D., Kim, Y. H., Park, A. & Ganz, T. (2001). Determinants of Staphylococcus aureus nasal carrtage. Clin Diagn Lab Immunol 8, 1064-1069.
5. Credo, R. B., Curtis, C. G. & Lorand, L. (1981). Alpha-chain domain of fibrinogen controls generation of fibrinoligase (coagulation factor XIIIa). Calcium ion regulatory aspects. Biochemistry 20, 3770-3778.
6. Davis, S. L., Gurusiddappa, S., McCrea, K. W., Perkins, S. & Hook, M. (2001). SdrG, a fibrinogen-binding bacterial adhesin of the microbial surface components recognizing adhesive matrix molecules subfamily from Staphylococcus epidermidis, targets the thrombin cleavage site in the Bbeta chain. J Biol Chem 276, 27799-27805.
7. Doolittle, R. F. (1984). Fibrinogen and fibrin. Annu Rev Biochem 53, 195-229.
8. Duthie, E. S. & Lorenz, L. L. (1952). Staphylococcal coagulase; mode of action and antigenicity. J Gen Microbiol 6, 95-107.
9. Gorkun, O. V., Veklich, Y. I., Medved, L. V., Henschen, A. H. & Weisel, J. W. (1994). Role of the alpha C domains of fibrin in clot formation. Biochemistry 33, 6986-6997.
10. Gorkun, O. V., Henschen-Edman, A. H., Ping, L. F. & Lord, S. T. (1998). Analysis of A alpha 251 fibrinogen: the alpha C domain has a role in polymerization, albeit more subtle than anticipated from the analogous proteolytic fragment X. Biochemistry 37, 15434-15441.
11. Henschen, A. & McDonagh, J. (1986). In Fibrinogen, Fibrin and Factor XIII in Blood Coagulation, pp. 171-241. Edited by R. F. A. Zwaal & H. C. Hemker. Amsterdam: Elsevier Science Publishers.
12. Herrick, S., Blanc-Brude, O., Gray, A. & Laurent G. (1999). Fibrinogen. Int J Biochem Cell Biol 31, 741-746.
13. Jonsson, K., McDevitt D., McGavin, M. H., Patti, J. M. & Hook M. (1995). Staphylococcus aureus expresses a major histocompatibility complex class II analog. J Biol Chem 270, 21457-21460.
14. Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
15. Lord, S. T. (1985). Expression of a cloned human fibrinogen cDNA in Escherichia coli synthesis of an A alpha polypeptide. DNA 4, 33-38.
16. Mazmanian, S. K., Liu, G., Ton-That, H. & Schneewind, O. (1999). Staphylococcus aureus sortase, an enzyme that anchors surface proteins to the cell wall. Science 285, 760-763.
17. McAleese, F. M., Walsh, E. J., Sieprawska, M., Potempa, J. & Foster, T. J. (2001). Loss of clumping factor B fibrinogen binding activity by Staphylococcus aureus involves cessation of transcription, shedding and cleavage by metalloprotease. J Biol Chem 276, 29969-29978.
18. McDevitt, D., Francois, P., Vaudaux, P. & Foster, T. J. (1994). Molecular chacterization of the clumping factor (fibrinogen receptor) of Staphylococcus aureus. Mol Microbiol 11, 237-248.
19. McDevitt, D., Francois, P., Vaudaux, P. & Foster, T. J. (1995). Indentification of the ligand-binding domain of the surface-located fibrogen receptor (clumping factor) of Staphylococcus aureus. Mol Microbiol 16, 895-907.
20. McDevitt, D., Nanavaty, T., House-Pompeo, K., Bell, E., Turner, N., McIntire, L., Foster, T. & Hook M. (1997). Characterization of the interaction between the Staphylococcus aureus clumping factor (ClfA) and fibrinogen. Eur J Biochem 247, 416-424.
21. McGavin, M. H., Krajewska-Pietrasik D., Ryden, C. & Hook, M. (1993). Identification of a Staphylococcus aureus extracellular matrix-binding protein with broad specificity. Infect Immun 61, 2479-2485.
22. Medved, L. V., Gorkun, O. V. & Privalov, P. L. (1983). Structural organization of C-terminal parts of fibrinogen A alpha-chains. FEBS Lett 160, 291-295.
23. Medved, L. V., Gorkun, O. V., Manyakov, V. F. & Belitser, V. A. (1985). The role of fibrinogen alpha C-domains in the fibrin assembly process. FEBS Lett 181, 109-112.
24. Miajlovic, H., Loughman, A., Brennan, M., Cox, D. & Foster, T. J. (2007). Both complement- and fibrinogen-dependent mechanisms contribute to platelet aggregation mediated by Staphylococcus aureus dumping factor B. Infect Immun 75, 3335-3343.
25. Navarre, W. W. & Schneewind, O. (1994). Proteolytic cleavage and cell wall anchoring at the LPXTG motif of surface proteins in gram-positive bacteria. Mol Microbiol 14, 115-121.
26. Ni Eidhin, D., Perkins, S., Francois, P., Vaudaux, P., Hook, M. & Foster, T. J. (1998). Clumping factor B (ClfB), a new surface-located fibrinogen-binding adhesin of Staphylococcus aureus. Mol Microbiol 30, 245-257.
27. O'Brien, L. M., Walsh, E. J., Massey, R. C., Peacock, S. J. & Foster, T. J. (2002). Staphylococcus aureus clumping factor B (ClfB) promotes adherence to human type I cytokeratin 10: implications for nasal colonization. Cell Microbiol 4, 759-770.
28. 2+ -dependent inhibitory site. J Biol Chem 273, 6821-6829.
29. Palma, M., Wade, D., Flock, M. & Flock J. I. (1998). Multiple binding sites in the interaction between an extracellular fibrinogen-binding protein from Staphylococcus aureus and fibrinogen. J Biol Chem 273, 13177-13181.
30. Peacock, S. J., de Silva, I. & Lowy, F. D. (2001). What determines nasal carriage ot Staphylococtus aureus? Trends Microbiol 9, 605-610.
31. Perkins, S., Walsh, E. J., Deivanayagam, C. C., Narayana, S. V., Foster, T. J. & Hook, M. (2001). Structural organization of the fibrinogen-bindihg region of the clumping factor B MSCRAMM of Staphylococcus aureus. J Biol Chem 276, 44721-44728.
32. Phonimdaeng, P., O'Reilly, M., Nowlan, P., Bramley, A. J. & Foster, T. J. (1990). The coagulase of Staphylococcus aureus 8325-4. Sequence analysis and virulence of site-specific coagulase-deficient mutants. Mol Microbiol 4, 393-404.
33. Ponnuraj, K., Bowden, M. G., Davis, S., Gurusiddappa, S., Moore D., Choe, D., Xu, Y., Hook, M. & Narayana, S. V. (2003). A "dock, lock, and latch structural model for a staphylococcal adhesin binding to fibrinogen. Cell 115, 217-228.
34. Rudchenko, S., Trakht, I. & Sobel, J. H. (1996). Comparative structural and functional features of the human fibrinogen alpha C domain and the isolated alpha C fragment. Characterization using monoclonal antibodies to defined COOH-terminal A alpha chain regions. J Biol Chem 271, 2523-2530.
35. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989). Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Labratory.
36. Tsurupa, G. & Medved, L. (2001). Identification and characterization of novel tPA- and plasminogen-binding sites within fibrin(ogen) alpha C-domains. Biochemistry 40, 801-808.
37. Tsurupa, G., Tsonev, L. & Medved, L. (2002). Structural organization of the fibrin(ogen) alpha C-domain. Biochemistry 41, 6449-6459.
38. Walsh, E. J., O'Brien, L. M., Liang, X., Hook, M. & Foster, T. J. (2004). Clumping factor B, a fibrinogen-binding MSCRAMM (microbial surface components recognizing adhesive matrix molecules) adhesin of Staphylococcus aureus, also binds to the tail region of type I cytokeratin 10. J Biol Chem 279, 50691-50699.
39. Wann, E. R., Gurusiddappa, S. & Hook, M. (2000). The fibronectin-binding MSCRAMM FnbpA of Staphylococcus aureus is a bifunctional protein that also binds to fibrinogen. J Biol Chem 275, 13863-13871.
40. Weisel, J. W. & Medved, L. (2001). The structure and function of the αC domains of fibrinogen. Ann N Y Acad Sci 936, 312-327.
41. Yang, Z., Kollman, J. M., Pandi, L. & Doolittle, R. F. (2001). Crystal structure of native chicken fibrinogen at 2.7 Å resolution. Biochemistry 40, 12515-12523.