Progressive encephalomyelitis with rigidity and myoclonus in an 81-year-old patient

Clinical Neurology and Neurosurgery

Volumn 110, Issue 3, 2008, Pages 279-281

  Kraemer, Markus ^a   Berlit, Peter ^a  

^a Alfried Krupp von Bohlen und Halbach Hospital   (Germany)

Author keywords

Paraneoplastic Stiff Person syndrome; Progressive encephalomyelitis with rigidity and myoclonus; Stiff Person syndrome

Indexed keywords

BACLOFEN; BENZODIAZEPINE; CORTICOSTEROID; IMMUNOGLOBULIN; METHYLPREDNISOLONE; PREDNISONE; VIGABATRIN;

AGED; ARTICLE; AUTOIMMUNE DISEASE; CASE REPORT; COGNITIVE DEFECT; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG MEGADOSE; ENCEPHALOMYELITIS; FEMALE; HASHIMOTO DISEASE; HUMAN; MUSCLE RIGIDITY; MUSCLE SPASM; MYOCLONUS; NEUROIMAGING; NEUROLOGIC EXAMINATION; PARANEOPLASTIC SYNDROME; STIFF MAN SYNDROME;

AGED, 80 AND OVER; ANTI-INFLAMMATORY AGENTS; BACLOFEN; ELECTROMYOGRAPHY; ENCEPHALOMYELITIS; FEMALE; GAIT DISORDERS, NEUROLOGIC; HUMANS; IMMUNOGLOBULINS; MAGNETIC RESONANCE IMAGING; MUSCLE RELAXANTS, CENTRAL; MUSCLE RIGIDITY; MYOCLONUS; NEUROLOGIC EXAMINATION; PREDNISONE;

EID: 39749112017     PISSN: 03038467     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clineuro.2007.10.004     Document Type: Article

References (13)

1. Meinck H.M., and Thompson P.D. Stiff Person syndrome and related conditions. Mov Disorders 17 (2002) 853-866
2. Berger C., and Meinck H.M. Head retraction reflex in Stiff-man syndrome and related disorders. Mov Disorders 18 (2003) 906-911
3. Campbell A.M.G., and Garland H. Subacute myoclonic spinal neuronitis. J Neurol Neurourg Psychiatry 19 (1956) 268-274
4. Whitely A.M., Swash M., and Ulrich H. Progressive encephalomyelitis with rigidity. Its relation to "subacute myoclonic spinal neuronitis" and to "Stiff man syndrome". Brain 99 (1976) 27-42
5. Murinson B.B. Stiff-Person syndrome. Neurologist 10 (2004) 131-137
6. Dalakas M.C., Fujii M., Li M., and McElroy B. The clinical spectrum of anti-GAD antibody positive patients with Stiff-Person syndrome. Neurology 55 (2000) 1531-1535
7. Bateman D.E., Weller R.O., and Kennedy P. Stiffman syndrome: a rare paraneoplastic disorder?. J Neurol Neurosurg Psychiatry 53 (1990) 695-696
8. Meinck H.M., Faber L., Morgenthaler N., Seisseler J., Maile S., Butler M., et al. Antibodies against glutamic acid decarboxylase: prevalence in neurological diseases. J Neurol Neurosurg Psychiatry 71 (2001) 100-103
9. Folli F., Solimena M., Cofiell R., Austoni M., Tallini G., Fassetta G., et al. Autoantibodies to a 128-kd synaptic protein in three women with the stiff-man syndrome and breast cancer. N Engl J Med 328 (1993) 546-551
10. Ramos-Casals M., Garcia-Carrasco M., Brito M.P., Lopez-Soto A., and Font J. Autoimmunity and geriatrics: clinical significance of autoimmune manifestations in the elderly. Lupus 12 (2003) 341-355
11. Meinck H.M., Ricker K., and Conrad B. The Stiff-man syndrome: new pathophysiological aspects from abnormal exteroceptive reflexes and the response to clomipramin, clonidin and tizanidin. J Neurol Neurosurg Psychiatry 47 (1984) 280-287
12. Barker R.A., and Marsden C.D. Successful treatment of Stiff-man syndrome with intravenous immunoglobulin. J Neurol Neurosurg Psychiatry 62 (1997) 426-427
13. Gerschlager W., and Brown P. effect of treatment with intravenous immunoglobuline on quality of life in patients with Stiff-Person syndrome. Movement Disorders 17 (2002) 590-593