Should we be using calcium-containing phosphate binders in patients on dialysis?

Nature Clinical Practice Nephrology

Volumn 4, Issue 3, 2008, Pages 118-119

  Spiegel, David M ^a   Block, Geoffrey A ^b  

^a UNIVERSITY OF COLORADO   (United States)

^b Denver Nephrologists   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM; BETA 2 MICROGLOBULIN; CALCITRIOL; CALCIUM; CALCIUM CARBONATE; GADOLINIUM; PHOSPHATE BINDING AGENT; SEVELAMER; VITAMIN D DERIVATIVE;

BLOOD VESSEL CALCIFICATION; COST BENEFIT ANALYSIS; DIALYSATE; DIALYSIS; DRUG EFFICACY; DRUG SAFETY; HEMODIALYSIS PATIENT; HUMAN; MORBIDITY; MORTALITY; NONHUMAN; NOTE; PATIENT CARE; PREVALENCE; PRIORITY JOURNAL;

CALCIUM COMPOUNDS; CHELATING AGENTS; HUMANS; HYPERCALCEMIA; HYPERPHOSPHATEMIA; RENAL DIALYSIS;

EID: 39749110276     PISSN: 17458323     EISSN: 17458331     Source Type: Journal    
DOI: 10.1038/ncpneph0710     Document Type: Note

References (11)

1. Shroff RC and Shanahan CM (2007) The vascular biology of calcification. Semin Dial 20: 103-109
2. Yang H et al. (2004) Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro. Kidney Int 66: 2293-2299
3. London GM et al. (2003) Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality. Nephrol Dial Transplant 18: 1731-1740
4. Chertow GM et al. (2002) Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients. Kidney Int 62: 245-252
5. Block GA et al. (2005) Effects of sevelamer and calcium on coronary artery calcification in patients new to hemodialysis. Kidney Int 68: 1815-1824
6. Russo D et al. (2007) The progression of coronary artery calcification in predialysis patients on calcium carbonate or sevelamer. Kidney Int 72: 1255-1261
7. Block GA et al. (2007) Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients. Kidney Int 71: 438-441
8. Suki WN et al. (2007) Effects of sevelamer and calcium-based phosphate binders on mortality in hemodialysis patients. Kidney Int 72: 1130-1137
9. Manns B et al. (2007) Economic evaluation of sevelamer in patients with end-stage renal disease. Nephrol Dial Transplant 22: 2867-2878
10. Moe SM and Chertow GM (2006) The case against calcium-based phosphate binders. Clin J Am Soc Nephrol 1: 697-703
11. Kalantar-Zadeh K et al. (2006) Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients. Kidney Int 70: 771-780