Induction of growth arrest and apoptosis in human breast cancer cells by 3,3-diindolylmethane is associated with induction and nuclear localization of p27kip

Molecular Cancer Therapeutics

Volumn 7, Issue 2, 2008, Pages 341-349

  Wang, Zhiwei ^a   Yu, Bennett W ^b   Rahman, K M Wahidur ^a   Ahmad, Fakhara ^a   Sarkar, Fazlul H ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Medical Oncology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3,3 DIINDOLYLMETHANE; CYCLIN DEPENDENT KINASE INHIBITOR 1B; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; INDOLE DERIVATIVE; PROTEIN KINASE B; THREONINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CANCER PREVENTION; CELL FRACTIONATION; CELL LINE; CELL LOSS; CELL STRAIN; CELL STRAIN MCF 7; CELL VIABILITY; CHEMOPROPHYLAXIS; CONFOCAL MICROSCOPY; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; GROWTH INHIBITION; HALF LIFE TIME; HUMAN; HUMAN CELL; IC 50; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION;

APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, ERBB-2; HALF-LIFE; HUMANS; INDOLES; ONCOGENE PROTEIN V-AKT; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 39749107928     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-07-0476     Document Type: Article

References (41)