Comparisons of short- and intermediate-term effects of pitavastatin versus atorvastatin on lipid profiles, fibrinolytic parameter, and endothelial function

International Journal of Cardiology

Volumn 125, Issue 1, 2008, Pages 136-138

  Sakabe, Koichi ^a   Fukuda, Nobuo ^a   Fukuda, Yamato ^a   Wakayama, Katsunori ^a   Nada, Teru ^a   Morishita, Satofumi ^a   Shinohara, Hisanori ^a   Tamura, Yoshiyuki ^a  

^a NATIONAL HOSPITAL ORGANIZATION   (Japan)

Author keywords

Endothelial function; Lipid; Pleiotropic effects; Statin

Indexed keywords

ATORVASTATIN; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PITAVASTATIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; FEMALE; FIBRINOLYSIS; HUMAN; HYPERCHOLESTEROLEMIA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; VASODILATATION;

AGED; ANTILIPEMIC AGENTS; CORONARY ARTERY DISEASE; ENDOTHELIUM, VASCULAR; FEMALE; FIBRINOLYSIS; HEPTANOIC ACIDS; HUMANS; HYPERCHOLESTEROLEMIA; LIPIDS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; PYRROLES; QUINOLINES; TIME FACTORS; VASODILATION;

EID: 39749102894     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2007.01.040     Document Type: Article

References (6)

1. Marchesi S., Lupatteli G., Siepi D., et al. Short-term atorvastatin treatment improves endothelial function in hypercholesterolemic women. J Cardiovasc Pharmacol 36 (2000) 617-621
2. Sakabe K., Fukuda N., Wakayama K., Nada T., Shinohara H., and Tamura Y. Effects of atorvastatin therapy on the low-density lipoprotein subfraction, remnant-like particles cholesterol, and oxidized low-density lipoprotein within 2 weeks in hypercholesterolemic patients. Circ J 67 (2003) 866-870
3. Sakabe K., Fukuda N., Wakayama K., Nada T., Shinohara H., and Tamura Y. Lipid-altering changes and pleiotropic effects of atorvastatin in patients with hypercholesterolemia. Am J Cardiol 94 (2004) 497-500
4. Smilde T.J., van Wissen S., Wollersheim H., Trip M.D., Kastelein J.J., and Stalenhoef A.F. Effect of aggressive versus conventional lipid lowering on atherosclerosis progression in familial hypercholesterolaemia (ASAP): a prospective, randomized, double-blind trial. Lancet 357 (2001) 577-581
5. Laufs U., Fata V.L., Plutzky J., and Liao J. Upregulation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors. Circulation 97 (1998) 1129-1135
6. Wang J., Tokoro T., Matsui K., Higa S., and Kitajima I. Pitavastatin at low dose activates endothelial nitric oxide synthase through PI3K-AKT pathway in endothelial cells. Life Sci 76 (2005) 2257-2268