Cytopathic effect of classical swine fever virus NS3 protein on PK-15 cells

Intervirology

Volumn 50, Issue 6, 2008, Pages 433-438

  Xu, Hao ^a   Hong, Hai Xia ^a   Zhang, Yan Ming ^a   Guo, Kang Kang ^a   Deng, Xiao Ming ^a   Ye, Gui Sheng ^a   Yang, Xiao Yun ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

Apoptosis; Classical swine fever virus; Cytopathic effect

Indexed keywords

LIPOSOME; NONSTRUCTURAL PROTEIN 3; PLASMID VECTOR; RESTRICTION ENDONUCLEASE; VIRUS PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CYTOPATHOGENIC EFFECT; ENZYME DEGRADATION; GENETIC TRANSFECTION; HOST CELL; KIDNEY CELL; MOLECULAR CLONING; NONHUMAN; PESTIVIRUS; PRIORITY JOURNAL; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SWINE; VIRUS CELL INTERACTION; VIRUS STRAIN;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CLASSICAL SWINE FEVER; CLASSICAL SWINE FEVER VIRUS; CYTOPATHOGENIC EFFECT, VIRAL; PLASMIDS; SWINE; VIRAL NONSTRUCTURAL PROTEINS;

CLASSICAL SWINE FEVER VIRUS;

EID: 39749083904     PISSN: 03005526     EISSN: None     Source Type: Journal    
DOI: 10.1159/000113467     Document Type: Article

References (13)

1. Gresier-Wilke I, Haas L, Dittmar K, et al: RNA insertions and gene duplications in the nonstructural protein p125 region of pestivirus strains and isolated in vitro and in vivo. Virology 1993;193:977-980.
2. Meyers G, Thiel HJ: Molecular characterization of pestivirus. Adv Virus Res 1996;47:53-118.
3. Kümmerer BM, Tautz N, Becher P, Thiel HJ, Meyers G: The genetic basis for cytopathogenicity of pestiviruses. Vet Microbiol 2000;77:117-128.
4. Meyers G, Thiel HJ: Molecular characterization of pestiviruses. Adv Virus Res 1996;47:53-118.
5. Kummerer BM, Myers G: Correlation between point mutations in NS2 and the viability and cytopathogenicity of bovine viral diarrhea virus strain Oregon analyzed with an infectious cDNA clone. J Virol 2000;74:390-400.
6. Aoki H, Ishikawa K, Akoda Y, Sekiguchi H, Kodama M, Suzuki S, Fukusho A: Characterization of classical swine fever virus associated with defective interfering particles containing a cytopathogenic subgenomic RNA, which was isolated from wild boar. Vet Med Sci 2001;63:751-758.
7. Kosmidou A, Buttner M, Meyer G: Isolation and characterization of cytopathogenic classical swine fever virus (CSFV). Arch Virol 1998;143:1295-1309.
8. Meyers G, Thiel HJ: Cytopathogenicity of classical swine fever virus caused by defective interfering particles. J Virol 1995;69:3683-3689.
9. Meyers G, Thiel HJ, Rumenapf T: Classical swine fever virus: recovery of infectious viruses from cDNA constructs and generation of recombinant cytopathogenic defective interfering particles. J Virol 1996;70:1588-1595.
10. Mittelholzer C, Moser C, Tratschin JD, Hofmann MA: Generation of cytopathogenic subgenomic RNA of classical swine fever virus in persistently infected porcine cell lines. Virus 1997;51:125-137.
11. Kumagai T, Shimizu T, Matsumoto M: Detection of hog cholera virus by its effect on Newcastle disease virus in swine tissue culture. Science 1958;128:366.
12. Aoki H, Sakoda Y, Nakamura S, et al: Cytopathogenicity of classical swine fever viruses that do not show the exaltation of Newcastle disease virus is associated with accumulation of NS3 in serum-free cultured cell lines. Vet Med Sci 2004;66:161-167.
13. Wu HX: Construction of cytopathic PK-15 cell model of classical swine fever virus. Chin Sci Bull 2003;9:48-82.