Drug loading into β-cyclodextrin granules using a supercritical fluid process for improved drug dissolution

European Journal of Pharmaceutical Sciences

Volumn 33, Issue 3, 2008, Pages 306-312

  Hussein, Khaled ^a   Türk, Michael ^b   Wahl, Martin A ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF KARLSRUHE   (Germany)

Author keywords

Cyclodextrin granules; Controlled particle deposition; Enhanced dissolution; Ibuprofen; Supercritical fluid

Indexed keywords

BETA CYCLODEXTRIN; CAVAMAX; DRUG CARRIER; IBUPROFEN; MICROCRYSTALLINE CELLULOSE; SOLVENT; UNCLASSIFIED DRUG; WATER;

ARTICLE; CRYSTAL; DRUG GRANULE; DRUG MANUFACTURE; DRUG SOLUBILITY; IMMERSION; INTERMETHOD COMPARISON; MELTING POINT; PRIORITY JOURNAL; SUPERCRITICAL FLUID; SURFACE PROPERTY; THERMODYNAMICS; X RAY ANALYSIS;

BETA-CYCLODEXTRINS; CALORIMETRY, DIFFERENTIAL SCANNING; CELLULOSE; CRYSTALLIZATION; DRUG COMPOUNDING; IBUPROFEN; MICROSCOPY, ELECTRON, SCANNING; POVIDONE; SOLUBILITY; SURFACE PROPERTIES; X-RAY DIFFRACTION;

EID: 39649121034     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2008.01.003     Document Type: Article

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