Preparation of griseofulvin microparticles by supercritical fluid expansion depressurization process

Powder Technology

Volumn 182, Issue 3, 2008, Pages 459-465

  Zhiyi, Li ^a   Jingzhi, Jiang ^a   Xuewu, Liu ^a   Shunxuan, Zhao ^a   Yuanjing, Xia ^a   Jian, Wang ^a  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Griseofulvin; Microparticles; Supercritical fluid expansion depressurization

Indexed keywords

CONCENTRATION (PROCESS); MIXING; PARAMETER ESTIMATION; PARTICLE SIZE ANALYSIS;

GRISEOFULVIN; MICROPARTICLES; SUPERCRITICAL FLUID EXPANSION DEPRESSURIZATION;

SUPERCRITICAL FLUIDS;

ACETONE; ALCOHOL; GRISEOFULVIN;

CONCENTRATION (PROCESS); MIXING; PARAMETER ESTIMATION; PARTICLE SIZE ANALYSIS; SUPERCRITICAL FLUIDS;

ARTICLE; CONCENTRATION (PARAMETERS); DRUG COATING; DRUG FORMULATION; PARTICLE SIZE; PRESSURE; SOLVENT EXTRACTION; SUPERCRITICAL FLUID; TEMPERATURE;

EID: 39649115613     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2007.07.016     Document Type: Article

References (16)

1. Atkinson R.M., Bedford C., Child K.J., and Tomich E.G. Effect of particle size on blood-griseofulvin levels in man. Nature (February 10 1962)
2. Kraml M., Dubuc J., and Guadry R. Proc. R. Soc. Lond. 12 (1962) 239
3. Shariati A., and Peters C.J. Recent developments in particle design using supercritical fluids. Curr. Opin. Solid State Mater. Sci. 7 (2003) 371-383
4. Zhiyi L. Preparation of microparticles by rapid expansion of supercritical solution process. J. China Powder Sci. Technol. 6 5 (2000) 25-28
5. 2 with cosolvent acetone. Proc 6th Int Symp Supercrit Fluid vol. 3 (2003) 1725-1734
6. Kayrak D., Akman U., and Hortacsu O. Micronization of ibuprofen by RESS. J. Supercrit. Fluid 26 (2003) 17-31
7. Reverchon E., De Marco I., Caputo G., and Della Porta G. Pilotscale micronization of amoxicillin by supercritical antisolvent precipitation. J. Supercrit. Fluid 26 (2003) 1-7
8. Xuewu L., Zhiyi L., Bing H., and Taliang Y. Supercritical antisolvent precipitation of microparticles of quercetin. Chin. J. Chem. Eng. 13 1 (2005) 128-130
9. Reverchon E., Della Porta G., Taddeo R., Pallado P., and Stassi A. Solubility and micronization of griseofulvin in supercritical CHF3. Ind. Eng. Chem. Res. 34 11 (1995) 4087-4091
10. DeGioannis B., Jestin P., and PascaleSubra. Morphology and growth control of griseofulvin recrystallized by compressed carbon dioxide as antisolvent. J. Cryst. Growth 262 (2004) 519-526
11. Chen H., Lai J., Deng X., and Dai G. Fine griseofulvin particles formation by rapid expansion of supercritical solutions. J. Chem. Ind. Eng., China 52 1 (2001) 56-60
12. Xuewu L., Shunxuan Z., Jingzhi J., Zhiyi L., and Xiaodong Z. The development of preparation of water solvable drug microparticles by supercritical fluid. J. Chem. Ind. Eng. 26 2 (2005) 20-23
13. LiuXiaofeng DengXiu, Shen zhonghu. The study of improving griseofulvin solubility. J. Chinese Journal of Antibiotics, 1999, 24(6):417-418,452.
14. 2 on the solubility of griseofulvin in acetone and ethanol solutions. J. Supercrit. Fluids 29 (2004) 49-57
15. Han F., Xue Y., Tian Y., Zhao X., and Chen L. Vapor-Liquid Equilibria of the Carbon Dioxide+Acetone System at Pressures from (2.36 to 11.77) MPa and Temperatures from (333.15 to 393.15) K. J. Chem. Eng. Data 50 (2005) 36-39
16. 2. Chin. J. Chem. Eng. 9 3 (2001) 322-325