Relationships between densitometric and morphological parameters as measured by peripheral computed tomography and the compressive behavior of lumbar vertebral bodies from macaques (Macaca fascicularis)

Spine

Volumn 33, Issue 4, 2008, Pages 366-372

  Dickerson, Clark R ^a   Saha, Subrata ^b   Hotchkiss, Charlotte E ^c  

^a UNIVERSITY OF WATERLOO   (Canada)

^b SUNY DOWNSTATE MEDICAL CENTER   (United States)

^c NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Mechanical tolerance; Non invasive bone assessment; Tissue strength; Vertebrae

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DISEASE; COMPRESSION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DENSITOMETRY; FORCE; LUMBAR VERTEBRA; MACACA; MALE; MECHANICS; MORPHOLOGY; NONHUMAN; OSTEOPOROSIS; PRIORITY JOURNAL; REGRESSION ANALYSIS; STRESS; WEIGHT BEARING;

ANIMALS; BIOMECHANICS; BONE DENSITY; COMPRESSIVE STRENGTH; LINEAR MODELS; LUMBAR VERTEBRAE; MACACA FASCICULARIS; MALE; STRESS, MECHANICAL; TOMOGRAPHY, X-RAY COMPUTED; WEIGHT-BEARING;

EID: 39649106596     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e318163fa0a     Document Type: Article

References (32)

1. Owen RA, Melton LJ, Gallagher JC, et al. The national cost of acute care of hip fractures associated with osteoporosis. Clin Orthop 1980;150:172-6.
2. Keaveny TM, Hayes WC. A 20-year perspective on the mechanical properties of trabecular bone. J Biomech Eng (Transactions of ASME) 1993;115:534-42.
3. Carter DR, Hayes WC. Bone compressive strength: the influence of density and strain rate. Science 1976;194:1174-6.
4. Edmondston SJ, Singer KP, Day RE, et al. Ex vivo estimation of thoracolumbar vertebral body compressive strength: the relative contributions of bone densitometry and vertebral morphometry. Osteoporos Int 1997;7142-8.
5. Grote HJ, Amling M, Vogel M, et al. Intervertebral variation in trabecular microarchitecture throughout the normal spine in relation to age. Bone 1995;16:301-8.
6. Mosekilde L, Bentzen SM, Ortoft G, et al. The predictive value of quantitative computed tomography for vertebral body compressive strength and ash density. Bone 1989;10:465-70.
7. Silva MJ, Keaveny TM, Hayes WC. Computed tomography-based finite element analysis predicts failure loads and fracture patterns for vertebral sections. J Orthop Res 1998;16:300-8.
8. Brassow F, Crone-Munzebrock W, Weh L, et al. Correlations between breaking load and CT absorption values of vertebral bodies. Eur J Radiol 1982;2:99-101.
9. Cody DD, Goldstein SA, Flynn MJ, et al. Correlations between vertebral regional bone mineral density (rBMD) and whole bone fracture load. Spine 1991;16:146-54.
10. McBroom RJ, Hayes WC, Edwards WT, et al. Prediction of vertebral body compressive fracture using quantitative computed tomography. J Bone Joint Surg 1985;67A:1206-13.
11. Biggemann M, Hilweg D, Brinckmann P. Prediction of the compressive strength of vertebral bodies of the lumbar spine by quantitative computed tomography. Skeletal Radiol 1988; 1988;17:264-9.
12. Cheng XG, Nicholson PH, Bonnen S, et al. Prediction of vertebral strength in vitro by spinal bone densitometry and calcaneal ultrasound. J Bone Miner Res 1997;12:1721-8.
13. Hotchkiss CE. Use of peripheral quantitative computed tomography for densitometry of the femoral neck and spine in cynomolgus monkeys (Macaca fascicularis). Bone 1999;24:101-7.
14. Hansson TH, Roos B, Nachemson A. The bone mineral content and ultimate compressive strength of lumbar vertebrae. Spine 1980;5:46-55.
15. Eie N. Load capacity of the low back. J Oslo City Hosp 1966;4:75-98.
16. Roaf R. A study of the mechanics of spinal injuries. J Bone Joint Surg 1960;42:810-23.
17. Eriksson SA, Isberg BO, Lindgren JU. Prediction of vertebral strength by dual photon absorptiometry and quantitative computed tomography. Calcif Tiss Int 1989;44:243-50.
18. Myers BS, Arbogast KB, Lobaugh B, et al. Improved assessment of lumbar vertebral body strength using supine lateral dual-energy X-ray absorptiometry. J Bone Miner Res 1994;9:687-93.
19. Singer K, Edmonston S, Day R, et al. Prediction of thoracic and lumbar vertebral body compressive strength: correlations with bone mineral density and vertebral region. Bone 1995;17:167-74.
20. Veenland JF, Link TM, Konermann W, et al. Unraveling the role of structure and density in determining vertebral bone strength. Calcif Tissue Int 1997;61:474-9.
21. Mosekilde LI, Mosekilde LE. Iliac crest trabecular bone volume as predictor for vertebral compressive strength, ash density and trabecular bone volume in normal individuals. Bone 1998;9:195-9.
22. Ortoft G, Mosekilde LI, Hasling C, et al. Estimation of vertebral body strength by dual photon absorptiometry in elderly individuals: comparison between measurements of total vertebral and vertebral body bone mineral. Bone 1993;14:667-73.
23. Mazess RB, Barden H, Mautalen C, et al. Normalization of spine densitometry. J Bone Miner Res 1994;9:541-8.
24. Gilsanz V, Loro ML, Roe TF, et al. Vertebral size in elderly women with osteoporosis. J Clin Invest 1995;95:2332-7.
25. Veenland JF, Link TM, Konermann W, et al. Unraveling the role of structure and density in determining vertebral bone strength. Calcif Tissue Int 1997;61:474-9.
26. Rockoff SD, Sweet E, Bleustein J. The relative contribution of trabecular and cortical bone to the strength of human lumbar vertebrae. Calc Tiss Res 1969;3:164-75.
27. Hansson TH, Keller TS, Panjabi MM. A study of the compressive properties of lumbar vertebral trabeculae: effects of tissue characteristics. Spine 1986;11:56-62.
28. Mosekilde LI, Mosekilde LE. Sex differences in age-related changes in vertebral body size, density and biomechanical competence in normal individuals. Bone 1990;11:67-73.
29. Donovan DM. Correlation of vertebral body strength with QCT mineral density measurements. Master's Thesis, Clemson University, 1988.
30. Andresen R, Werner HJ, Schober HC. Contribution of the cortical shell of vertebrae to mechanical behaviour of the lumbar vertebrae with implications for prediction fracture risk. Br J Radiol 1998;71:759-65.
31. Silva MJ, Wang C, Keaveny TM, et al. Direct and computed tomography thickness measurements of the human, lumbar vertebral shell and endplate. Bone 1994;15:409-14.
32. Parkinson RJ, Durkin JL, Callaghan JP. Estimating the compressive strength of the porcine cervical spine: an examination of the utility of DXA. Spine 2005;30:E492-E498.