Hematogenous infection of Sprague-Dawley rats with Mycoplasma pulmonis: development of a model for maternal and fetal infection

American Journal of Obstetrics and Gynecology

Volumn 198, Issue 3, 2008, Pages 318.e1-318.e7

  Riggs, Margaret A ^a,b   Maunsell, Fiona P ^a   Reyes, Leticia ^a   Brown, Mary B ^a  

^a University of Florida College of Veterinary Medicine   (United States)

^b U S PUBLIC HEALTH SERVICE   (United States)

Author keywords

animal model; fetal infection; intrauterine infection

Indexed keywords

AMNION FLUID; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; BACTERIAL COLONIZATION; BACTERIAL INFECTION; BACTERIUM COLONY; BACTERIUM CULTURE; COLONY FORMING UNIT; CONCENTRATION RESPONSE; CONTROLLED STUDY; EXPERIMENTAL MODEL; FETUS; GESTATIONAL AGE; HISTOPATHOLOGY; IMMUNE RESPONSE; INFECTION RATE; INNATE IMMUNITY; INOCULATION; INTRAUTERINE INFECTION; MATERNAL DISEASE; MATERNAL INFECTION; MYCOPLASMA PULMONIS; NONHUMAN; PLACENTA; PREGNANCY; PREGNANCY OUTCOME; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SPRAGUE DAWLEY RAT; TISSUE CULTURE;

EID: 39649093408     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2007.09.042     Document Type: Article

References (31)

1. Goncalves L.F., Chaiworapongsa T., and Romero R. Intrauterine infection and prematurity. Ment Retard Dev Disabil Res Rev 8 (2002) 3-13
2. Lyon A. Chronic lung disease of prematurity. The role of intra-uterine infection. Eur J Pediatr 159 (2000) 798-802
3. Romero R., Espinoza J., Chaiworapongsa T., and Kalache K. Infection and prematurity and the role of preventive strategies. Semin Neonatol 7 (2002) 259-274
4. Romero R., Espinoza J., Kusanovic J.P., et al. The preterm parturition syndrome. BJOG 113 Suppl 3 (2006) 17-42
5. Romero R., Espinoza J., Goncalves L.F., Kusanovic J.P., Friel L.A., and Nien J.K. Inflammation in preterm and term labour and delivery. Semin Fetal Neonatal Med 11 (2006) 317-326
6. Romero R., Espinoza J., Goncalves L.F., Kusanovic J.P., Friel L., and Hassan S. The role of inflammation and infection in preterm birth. Semin Reprod Med 25 (2007) 21-39
7. Wu Y.W., Escobar G.J., Grether J.K., Croen L.A., Greene J.D., and Newman T.B. Chorioamnionitis and cerebral palsy in term and near-term infants. Obstet Gynecol Surv 59 (2004) 334-336
8. Yoon B.H., Romero R., Kim M., et al. Clinical implications of detection of Ureaplasma urealyticum in the amniotic cavity with the polymerase chain reaction. Am J Obstet Gynecol 183 (2000) 1130-1137
9. Berger A., Witt A., Haiden N., Kretzer V., Heinze G., and Kohlhauser C. Microbial invasion of the amniotic cavity at birth is associated with adverse short-term outcome of preterm infants. J Perinat Med 31 (2003) 115-121
10. Goldenberg R., Hauth J., and Andrews W. Intrauterine infection and preterm delivery. N Engl J Med 342 (2000) 1500-1507
11. Goldenberg R.L., Andrews W.W., Faye-Petersen O.M., Goepfert A.R., Cliver S.P., and Hauth J.C. The Alabama Preterm Birth Study: intrauterine infection and placental histologic findings in preterm births of males and females less than 32 weeks. Am J Obstet Gynecol 195 (2006) 1533-1537
12. Knox C.L., Cave D.G., Farrell D.J., Eastment H.T., and Timms P. The role of Ureaplasma urealyticum in adverse pregnancy outcome. Aust New Zeal J Obstet Gynaecol 37 (1997) 45-51
13. Romero R., Nores J., Mazor M., et al. Microbial invasion of the amniotic cavity during term labor: prevalence and clinical significance. J Reprod Med 38 (1993) 543-548
14. Yoon B.H., Romero R., Lim J.H., et al. The clinical significance of detecting Ureaplasma urealyticum by the polymerase chain reaction in the amniotic fluid of patients with preterm labor. Am J Obstet Gynecol 189 (2003) 919-924
15. Witt A., Berger A., Gruber C.J., Petricevic L., Apfalter P., and Husslein P. IL-8 concentrations in maternal serum, amniotic fluid and cord blood in relation to different pathogens within the amniotic cavity. J Perinat Med 33 (2005) 22-26
16. Witt A., Berger A., Gruber C.J., et al. Increased intrauterine frequency of Ureaplasma urealyticum in women with preterm labor and preterm premature rupture of the membranes and subsequent cesarean delivery. Am J Obstet Gynecol 193 (2005) 1663-1669
17. Abele-Horne M., Scholz M., Wolff C., and Kolben M. High-density vaginal Ureaplasma urealyticum colonization as a risk factor for chorioamnionitis and preterm delivery. Acta Obstet Gynecol Scand 79 (2000) 973-978
18. Theilen U., Lyon A.J., Fitzgerald T., Hendry G.M., and Keeling J.W. Infection with Ureaplasma urealyticum: is there a specific clinical and radiological course in the preterm infant?. Arch Dis Child Fetal Neonatal Ed 89 (2004) F163-F167
19. Waites K.B., Katz B., and Schelonka R.L. Mycoplasmas and ureaplasmas as neonatal pathogens. Clin Microbiol Rev 18 (2005) 757-789
20. Brown M.B., Peltier M., Hillier M., Crenshaw B., and Reyes L. Genital mycoplasmosis in rats: a model for intrauterine infection. Am J Reprod Immun 46 (2001) 232-241
21. Brown M.B., and Reyes L. Immunoglobulin class- and subclass-specific responses to Mycoplasma pulmonis in sera and secretions of naturally infected Sprague-Dawley female rats. Infect Immun 59 (1991) 2181-2185
22. Brown M.B., and Steiner D.A. Experimental genital mycoplasmosis: time of infection influences pregnancy outcome. Infect Immun 64 (1996) 2315-2321
23. Peltier M.R., Richey L.J., and Brown M.B. Placental lesions caused by experimental infection of Sprague-Dawley rats with Mycoplasma pulmonis. Am J Reprod Immunol 50 (2003) 254-262
24. Reyes L., Steiner D.A., Hutchison J., Crenshaw B., and Brown M.B. Mycoplasma pulmonis genital disease: effect of rat strain on pregnancy outcome. Comp Med 50 (2000) 622-627
25. Steiner D.A., and Brown M.B. Impact of experimental genital mycoplasmosis on pregnancy outcome in Sprague-Dawley rats. Infect Immun 61 (1993) 633-639
26. Steiner D.A., Uhl E.W., and Brown M.B. In utero transmission of Mycoplasma pulmonis in experimentally infected Sprague-Dawley rats. Infect Immun 61 (1993) 2985-2990
27. Davies J., and Glasser S.R. Histological and fine structural observations on the placenta of the rat. Acta Anat 69 (1968) 542-608
28. Redline R.W. Placental inflammation. Semin Neonatol 9 (2004) 265-274
29. Bailao L.A., Osborne N.G., Rizzi M.C., Bonilla-Musoles F., Duarte G., and Bailao T.C. Ultrasound markers of fetal infection part 1: viral infections. Ultrasound Q 21 (2005) 295-308
30. Bittencourt A.L., and Garcia A.G. The placenta in hematogenous infections. Pediatr Pathol Mol Med 21 (2002) 401-432
31. Gomez R., Romero R., Ghezzi F., Yoon B.H., Mazor M., and Berry S.M. The fetal inflammatory response syndrome. Am J Obstet Gynecol 179 (1998) 194-202