Empirical significance values for linkage analysis: Trait simulation using posterior model distributions from MCMC oligogenic segregation analysis

Genetic Epidemiology

Volumn 32, Issue 2, 2008, Pages 119-131

  Igo Jr , Robert P ^a   Wijsman, Ellen M ^b,c,d  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d NONE   (United States)

Author keywords

Complex traits; General pedigrees; Hypothesis testing; Marker simulation; Null distribution; Trait simulation

Indexed keywords

ARTICLE; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC TRAIT; PROBABILITY; SEGREGATION ANALYSIS; SIMULATION; STATISTICAL ANALYSIS;

BAYES THEOREM; COMPUTER SIMULATION; GENETIC MARKERS; HUMANS; LINKAGE (GENETICS); MARKOV CHAINS; MODELS, STATISTICAL; MONTE CARLO METHOD; PEDIGREE; QUANTITATIVE TRAIT LOCI;

EID: 39649089397     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20267     Document Type: Article

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