A simple chemical method for synthesizing malonyl hemiesters of 21-hydroxypregnanes, potential intermediates in cardenolide biosynthesis

Steroids

Volumn 73, Issue 4, 2008, Pages 458-465

  Pádua, Rodrigo M ^a   Waibel, Reiner ^a   Kuate, Serge Philibert ^a   Schebitz, Pia K ^a   Hahn, Stefanie ^a   Gmeiner, Peter ^a   Kreis, Wolfgang ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

21 Hydroxypregnane; Butenolide ring; Cardiac glycoside; Digitalis; Malonylation; Malonyltransferase

Indexed keywords

3 BETA ACETOXY 5 BETA PREGNANE 14 BETA 21 DIOL 20 ONE; CARDENOLIDE; DEOXYCORTICOSTERONE; PREGNANE DERIVATIVE; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; HORMONE SYNTHESIS; HYDROLYSIS; NUCLEAR OVERHAUSER EFFECT; OZONOLYSIS; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION; STRUCTURE ANALYSIS; SYNTHESIS;

4-BUTYROLACTONE; CARDENOLIDES; DIGITOXIGENIN; ESTERS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MOLECULAR STRUCTURE; PREGNANES; PREGNENOLONE;

EID: 39549120415     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2007.12.012     Document Type: Article

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