Comparison of the distribution of glial fibrillary acidic protein, heat shock protein 60, and hypoxia, inducible factor-1β in retinas from glaucomatous and normal canine eyes

American Journal of Veterinary Research

Volumn 69, Issue 2, 2008, Pages 265-272

  Savagian, Caitlin A ^a   Dubielzig, Richard R ^a   Nork, T Michael ^b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; HEAT SHOCK PROTEIN 60; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CLOSED ANGLE GLAUCOMA; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DOG DISEASE; FEMALE; GLAUCOMA; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; OPTIC NERVE ATROPHY; PATHOPHYSIOLOGY; PROTEIN LOCALIZATION; RETINA CELL; TISSUE DISTRIBUTION;

ANIMALS; CHAPERONIN 60; DOG DISEASES; DOGS; GLAUCOMA; GLIAL FIBRILLARY ACIDIC PROTEIN; HYPOXIA-INDUCIBLE FACTOR 1; RETINA;

EID: 39549103436     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.69.2.265     Document Type: Article

References (35)

1. Whiteman AL, Klauss G, Miller PE, et al. Morphologic features of degeneration and cell death in the neurosensory retina in dogs with primary angle-closure glaucoma. Am J Vet Res 2002;63:257-261.
2. Dkhissi O, Chanut E, Wasowicz M, et al. Retinal TUNEL-positive cells and high glutamate levels in vitreous humor of mutant quail with a glaucoma-like disorder. Invest Ophthalmol Vis Sci 1999;40:990-995.
3. Nork TM, Ver Hoeve JN, Poulsen GL, et al. Swelling and loss of photoreceptors in chronic human and experimental glaucomas. Arch Ophthalmol 2000;118:235-245.
4. Panda S, Jonas JB. Decreased photoreceptor count in human eyes with secondary angle-closure glaucoma. Invest Ophthalmol Vis Sci 1992;33:2532-2536.
5. Panda S, Jonas JB. Inner nuclear layer of the retina in eyes with secondary angle-block glaucoma [in German]. Ophthalmologe 1992;89:468-471.
6. Madl JE, McIlnay TR, Powell CC, et al. Depletion of taurine and glutamate from damaged photoreceptors in the retinas of dogs with primary glaucoma. Am J Vet Res 2005;66:791-799.
7. Mcllnay TR, Gionfriddo JR, Dubielzig RR, et al. Evaluation of glutamate loss from damaged retinal cells of dogs with primary glaucoma. Am J Vet Res 2004;65:776-786.
8. Ottersen OP, Laake JH, Reichelt W, et al. Ischemic disruption of glutamate homeostasis in brain: quantitative immunocytochemical analyses. J Chem Neuroanat 1996;12:1-14.
9. Torp R, Arvin B, Le Peillet E, et al. Effect of ischaemia and reperfusion on the extra- and intracellular distribution of glutamate, glutamine, aspartate and GABA in the rat hippocampus, with a note on the effect of the sodium channel blocker BW1003C87. Exp Brain Res 1993;96:365-376.
10. Perlman JI, McCole SM, Pulluru P, et al. Disturbances in the distribution of neurotransmitters in the rat retina after ischemia. Curr Eye Res 1996;15:589-596.
11. Tezel G, Hernandez R, Wax MB. Immunostaining of heat shock proteins in the retina and optic nerve head of normal and glaucomatous eyes. Arch Ophthalmol 2000;118:511-518.
12. Dillmann WH. Heat shock proteins and protection against ischemic injury. Infect Dis Obstet Gynecol 1999;7:55-57.
13. Kirchhoff SR, Gupta S, Knowlton AA. Cytosolic heat shock protein 60, apoptosis, and myocardial injury. Circulation 2002; 105:2899-2904.
14. Bárdos JI, Ashcroft M. Negative and positive regulation of HIF-1: a complex network. Biochim Biophys Acta 2005;1755:107-120.
15. Bracken CP, Whitelaw ML, Peet DJ. The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses. Cell Mol Life Sci 2003;60:1376-1393.
16. Tezel G, Wax MB. Hypoxia-inducible factor 1alpha in the glaucomatous retina and optic nerve head. Arch Ophthalmol 2004;122:1348-1356.
17. Cummins EP, Taylor CT. Hypoxia-responsive transcription factors. Pflugers Arch 2005;450:363-371.
18. Wang L, Cioffi GA, Cull G, et al. Immunohistologic evidence for retinal glial cell changes in human glaucoma. Invest Ophthalmol Vis Sci 2002;43:1088-1094.
19. Erickson PA, Fisher SK, Guerin CJ, et al. Glial fibrillary acidic protein increases in Müller cells after retinal detachment. Exp Eye Res 1987;44:37-48.
20. Sethi CS, Lewis GP, Fisher SK, et al. Glial remodeling and neural plasticity in human retinal detachment with proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci 2005;46:329-342.
21. Nork TM, Wallow IHL, Sramek SJ, et al. Müller's cell involvement in proliferative diabetic retinopathy. Arch Ophthalmol 1987;105:1424-1429.
22. Osborne NN, Block F, Sontag KH. Reduction of ocular blood flow results in glial fibrillary acidic protein (GFAP) expression in rat retinal Müller cells. Vis Neurosci 1991;7:637-639.
23. Reilly CM, Morris R, Dubielzig RR. Canine goniodysgenesis-related glaucoma: a morphologic review of 100 cases looking at inflammation and pigment dispersion. Vet Ophthalmol 2005;8:253-258.
24. Nork TM, Millecchia LL, Poulsen G. Immunocytochemical localization of the retinoblastoma protein in the human eye and in retinoblastoma. Invest Ophthalmol Vis Sci 1994;35:2682-2692.
25. Nork TM, Poulsen GL, Millecchia LL, et al. p53 regulates apoptosis in human retinoblastoma. Arch Ophthalmol 1997;115:213-219.
26. Nork TM, Schwartz TL, Doshi HM, et al. Retinoblastoma. Cell of origin. Arch Ophthalmol 1995;113:791-802.
27. Pelzel HR, Schlamp CL, Poulsen GL, et al. Decrease of cone opsin mRNA in experimental ocular hypertension. Mol Vis 2006;12:1272-1282.
28. Shan YX, Liu TJ, Su HF, et al. Hsp10 and Hsp60 modulate Bcl-2 family and mitochondria apoptosis signaling induced by doxorubicin in cardiac muscle cells. J Mol Cell Cardiol 2003;35:1135-1143.
29. Suzuki H, Tomida A, Tsuruo T. Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia. Oncogene 2001;20:5779-5788.
30. Hammond EM, Giaccia AJ. The role of p53 in hypoxia-induced apoptosis. Biochem Biophys Res Commun 2005;331:718-725.
31. Piret JP, Mottet D, Raes M, et al. Is HIF-1alpha a pro- or an anti-apoptotic protein? Biochem Pharmacol 2002;64:889-892.
32. Ke Q, Costa M. Hypoxia-inducible factor-1 (HIF-1). Mol Pharmacol 2006;70:1469-1480.
33. Nork TM, Millecchia LL, Strickland BD, et al. Selective loss of blue cones and rods in human retinal detachment. Arch Ophthalmol 1995;113:1066-1073.
34. Kendell KR, Quigley HA, Kerrigan LA, et al. Primary open-angle glaucoma is not associated with photoreceptor loss. Invest Ophthalmol Vis Sci 1995;36:200-205.
35. Wygnanski T, Desatnik H, Quigley HA, et al. Comparison of ganglion cell loss and cone loss in experimental glaucoma. Am J Ophthalmol 1995;120:184-189.