A transgenic Tie2-GFP athymic mouse model; a tool for vascular biology in xenograft tumors

Biochemical and Biophysical Research Communications

Volumn 368, Issue 2, 2008, Pages 364-367

  Hillen, Femke ^a   Kaijzel, Eric L ^b   Castermans, Karolien ^a   Egbrink, Mirjam G A oude ^c   Löwik, Clemens W G M ^b   Griffioen, Arjan W ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

GFP vessels; Hemodynamics; In vivo; Intravital microscopy; Vasculogenic mimicry

Indexed keywords

ANGIOPOIETIN RECEPTOR; GREEN FLUORESCENT PROTEIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; EWING SARCOMA; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTRAVITAL MICROSCOPY; MICROSCOPY; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; STATISTICAL ANALYSIS; TRANSGENIC MOUSE; TUMOR BLOOD FLOW; TUMOR CELL PLASTICITY; TUMOR DIFFERENTIATION; TUMOR XENOGRAFT; VASCULOGENIC MIMICRY;

ANIMALS; DISEASE MODELS, ANIMAL; MICE; MICE, INBRED BALB C; MICE, NUDE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; MOLECULAR PROBE TECHNIQUES; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; RECEPTOR, TIE-2;

MUS; MUS MUSCULUS;

EID: 39549100578     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.01.080     Document Type: Article

References (16)

1. Carmeliet P. Angiogenesis in life, disease and medicine. Nature 438 (2005) 932-936
2. Schlaeger T.M., Bartunkova S., Lawitts J.A., Teichmann G., Risau W., Deutsch U., and Sato T.N. Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice. Proc. Natl. Acad. Sci. USA 94 (1997) 3058-3063
3. Motoike T., Loughna S., Perens E., Roman B.L., Liao W., Chau T.C., Richardson C.D., Kawate T., Kuno J., Weinstein B.M., Stainier D.Y., and Sato T.N. Universal GFP reporter for the study of vascular development. Genesis 28 (2000) 75-81
4. van der Schaft D.W., Hillen F., Pauwels P., Kirschmann D.A., Castermans K., Egbrink M.G., Tran M.G., Sciot R., Hauben E., Hogendoorn P.C., Delattre O., Maxwell P.H., Hendrix M.J., and Griffioen A.W. Tumor cell plasticity in Ewing sarcoma, an alternative circulatory system stimulated by hypoxia. Cancer Res. 65 (2005) 11520-11528
5. Maniotis A.J., Folberg R., Hess A., Seftor E.A., Gardner L.M., Pe'er J., Trent J.M., Meltzer P.S., and Hendrix M.J. Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry. Am. J. Pathol. 155 (1999) 739-752
6. Hendrix M.J., Seftor E.A., Hess A.R., and Seftor R.E. Vasculogenic mimicry and tumour-cell plasticity: lessons from melanoma. Nat. Rev. Cancer 3 (2003) 411-421
7. Folberg R., Mehaffey M., Gardner L.M., Meyer M., Rummelt V., and Pe'er J. The microcirculation of choroidal and ciliary body melanomas. Eye 11 Pt 2 (1997) 227-238
8. Folberg R., Hendrix M.J., and Maniotis A.J. Vasculogenic mimicry and tumor angiogenesis. Am. J. Pathol. 156 (2000) 361-381
9. Clarijs R., Otte-Holler I., Ruiter D.J., and de Waal R.M. Presence of a fluid-conducting meshwork in xenografted cutaneous and primary human uveal melanoma. Invest. Ophthalmol. Vis. Sci. 43 (2002) 912-918
10. Smetsers T.F., van de Westerlo E.M., ten Dam G.B., Clarijs R., Versteeg E.M., van Geloof W.L., Veerkamp J.H., van Muijen G.N., and van Kuppevelt T.H. Localization and characterization of melanoma-associated glycosaminoglycans: differential expression of chondroitin and heparan sulfate epitopes in melanoma. Cancer Res. 63 (2003) 2965-2970
11. Chen X., Ai Z., Rasmussen M., Bajcsy P., Auvil L., Welge M., Leach L., Vangveeravong S., Maniotis A.J., and Folberg R. Three-dimensional reconstruction of extravascular matrix patterns and blood vessels in human uveal melanoma tissue: techniques and preliminary findings. Invest. Ophthalmol. Vis. Sci. 44 (2003) 2834-2840
12. Shirakawa K., Kobayashi H., Heike Y., Kawamoto S., Brechbiel M.W., Kasumi F., Iwanaga T., Konishi F., Terada M., and Wakasugi H. Hemodynamics in vasculogenic mimicry and angiogenesis of inflammatory breast cancer xenograft. Cancer Res. 62 (2002) 560-566
13. Kobayashi H., Shirakawa K., Kawamoto S., Saga T., Sato N., Hiraga A., Watanabe I., Heike Y., Togashi K., Konishi J., Brechbiel M.W., and Wakasugi H. Rapid accumulation and internalization of radiolabeled herceptin in an inflammatory breast cancer xenograft with vasculogenic mimicry predicted by the contrast-enhanced dynamic MRI with the macromolecular contrast agent G6-(1B4M-Gd)(256). Cancer Res. 62 (2002) 860-866
14. Ruf W., Seftor E.A., Petrovan R.J., Weiss R.M., Gruman L.M., Margaryan N.V., Seftor R.E., Miyagi Y., and Hendrix M.J. Differential role of tissue factor pathway inhibitors 1 and 2 in melanoma vasculogenic mimicry. Cancer Res. 63 (2003) 5381-5389
15. Dirkx A.E., Oude Egbrink M.G., Kuijpers M.J., van der Niet S.T., Heijnen V.V., Bouma-ter Steege J.C., Wagstaff J., and Griffioen A.W. Tumor angiogenesis modulates leukocyte-vessel wall interactions in vivo by reducing endothelial adhesion molecule expression. Cancer Res. 63 (2003) 2322-2329
16. Harder R., Uhlig H., Kashan A., Schutt B., Duijvestijn A., Butcher E.C., Thiele H.G., and Hamann A. Dissection of murine lymphocyte-endothelial cell interaction mechanisms by SV-40-transformed mouse endothelial cell lines: novel mechanisms mediating basal binding, and alpha 4-integrin-dependent cytokine-induced adhesion. Exp. Cell Res. 197 (1991) 259-267