The importance of schedule in whole body thermochemotherapy

International Journal of Hyperthermia

Volumn 24, Issue 2, 2008, Pages 171-181

  Bull, J M C ^a   Strebel, F R ^a   Jenkins, G N ^a   Deng, W ^a   Rowe, R W ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Cisplatin; Fever range whole body thermal therapy; Gemcitabine; Therapeutic index; Thermochemotherapy; Treatment scheduling

Indexed keywords

CISPLATIN; GEMCITABINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; AXILLARY LYMPH NODE; BOLUS INJECTION; BREAST ADENOCARCINOMA; CANCER CHEMOTHERAPY; CANCER CONTROL; CANCER INHIBITION; CANCER SURVIVAL; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG DOSE REDUCTION; DRUG EFFICACY; FEMALE; FISCHER 344 RAT; HYPERTHERMIC THERAPY; ISOGRAFT; LYMPH NODE METASTASIS; MAXIMUM TOLERATED DOSE; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; PROCESS OPTIMIZATION; RAT; RISK REDUCTION; TREATMENT PLANNING; TREATMENT RESPONSE; TUMOR GROWTH; WEIGHT REDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; COMBINED MODALITY THERAPY; DEOXYCYTIDINE; DRUG ADMINISTRATION SCHEDULE; FEMALE; HYPERTHERMIA, INDUCED; MAMMARY NEOPLASMS, ANIMAL; NEOADJUVANT THERAPY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 39549083224     PISSN: 02656736     EISSN: 14645157     Source Type: Journal    
DOI: 10.1080/02656730701883212     Document Type: Article

References (42)

1. Sakaguchi, Y., Makino, M., Kaneko, T., Stephens, LC, Strebel, FR, Danhauser, LL, Jenkins, GN and Bull, JM (1994) Therapeutic efficacy of long duration-low temperature whole body hyperthermia when combined with tumor necrosis factor and carboplatin in rats. Cancer Res, 54, pp. 2223-2227.
2. Ohno, S., Strebel, FR, Stephens, LC, Siddik, ZH, Baba, H., Makino, M., Khokhar, AR and Bull, JM (1993) Haematological toxicity of carboplatin and cisplatin combined with whole body hyperthermia in rats. Br J Cancer, 68, pp. 469-474.
3. Haveman, J., Van Der Zee, J., Wondergem, J., Hoogeveen, JF and Hulshof, MC (2004) Effects of hyperthermia on the peripheral nervous system: A review. Int J Hyperthermia, 20, pp. 371-391.
4. Calvert, AH, Harland, SJ, Newell, DR, Jones, AC, McElwain, TJ, Raju, S., Wiltshaw, E., Smith, IE, Baker, JM, Peckham, MJ and Harrap, KR (1982) Early clinical studies with cis-diammine-1,1-cyclobutane dicarboylate platinum II. Cancer Chemother Pharmacol, 9, pp. 140-147.
5. Strebel, FR, Proett, JM, Rowe, RW, Deng, W. and Bull, JMC (2006) Effect of oxaliplatin combined with fever-range whole body thermal-therapy in a rat mammary adenocarcinoma in vivo. Proc Amer Assoc Cancer Res, 47, p. 905.
6. Baba, H., Siddik, ZH, Strebel, FR, Jenkins, GN and Bull, JM (1989) Increased therapeutic gain of combined cis-diamminedichloroplatinum (II) and whole body hyperthermia therapy by optimal heat/drug scheduling. Cancer Res, 49, pp. 7041-7044.
7. Katschinski, DM, Wiedemann, GJ, Mentzel, M., Mulkerin, DL, Touhidi, R. and Robins, HI (1997) Optimization of chemotherapy administration for clinical 41.8°C whole body hyperthermia. Cancer Lett, 115, pp. 195-199.
8. Bull, JMC, Loo, CH, Strebel, FR, Jenkins, GN, Tomoda, M. and Rowe, RW (1999) Treatment of a highly metastatic mammary adenocarcinoma with fever-range, long-duration, low-temperature (40°C for 6 h) whole body hyperthermia (LL-WBH) combined with gemcitabine (dFdC) in rats. Proc Amer Assoc Cancer Res, 40, p. 552.
9. Bull, JMC, Strebel, FR, Jenkins, GN, Tomoda, M. and Rowe, RW (2000) Sequence dependency of antitumor effect of gemcitabine combined with cisplatin in the highly metastatic MTLN3 rat mammary adenocarcinoma. Proc Amer Assoc Cancer Res, 41, p. 410.
10. Evans, DP, Meyn, RE and Tomasovic, SP (1986) Survival of rat mammary tumor cell clones and DNA strand damage following adriamycin treatment. Cancer Chemother Pharmacol, 18, pp. 137-139.
11. Matsuda, H., Strebel, FR, Kaneko, T., Stephens, LC, Danhauser, LL, Jenkins, GN, Toyota, N. and Bull, JM (1996) Apoptosis and necrosis occurring during different stages of primary and metastatic tumor growth of a rat mammary adenocarcinoma. Anticancer Res, 16, pp. 1117-1121.
12. Matsuda, H., Strebel, FR, Kaneko, T., Danhauser, LL, Jenkins, GN, Toyota, N. and Bull, JM (1997) Long duration-mild whole body hyperthermia of up to 12 hours in rats: Feasibility, and efficacy on primary tumour and axillary lymph node metastases of a mammary adenocarcinoma: Implications for adjuvant therapy. Int J Hyperthermia, 13, pp. 89-98.
13. Baba, H., Siddik, ZH, Strebel, FR, Jenkins, GN and Bull, JM (1989) Increased therapeutic gain of combined cis-diamminedichloroplatinum (II) and whole body hyperthermia therapy by optimal heat/drug scheduling. Cancer Res, 49, pp. 7041-7044.
14. Wondergem, J., Strebel, FR, Siddik, ZH, Newman, RA and Bull, JM (1988) The effects of anaesthetics on cisplatinum-induced toxicity at normal temperatures and during whole body hyperthermia: The influence of NaCl concentration of the vehicle. Int J Hyperthermia, 4, pp. 643-654.
15. Lord, PF, Kapp, DS and Morrow, D. (1981) Increased skeletal metastases of spontaneous canine osteosarcoma after fractionated systemic hyperthermia and local X-irradiation. Cancer Res, 41, pp. 4331-4334.
16. Wondergem, J., Siddik, ZH, Strebel, FR and Bull, JM (1993) Effect of whole body hyperthermia on cis-diamminedichloroplatinum (II)-induced antitumour activity and tissue Pt-distribution: Do anaesthetics influence the therapeutic ratio?. Eur J Cancer, 29, pp. 549-554.
17. Shwartz, M., Pliskin, JS, Grondahl, HG and Boffa, J. (1984) Use of the Kaplan-Meier estimate to reduce biases in estimating the rate of caries progression. Community Dent Oral Epidemiol, 12, pp. 103-108.
18. Peschke, P., Heimburg, S., Wolber, G., Zuna, I. and Hahn, EW (1998) Improved therapeutic response by distinct timing of multiple heat treatments during interstitial radiation in the Dunning R3327 prostate tumor model. J Cancer Res Clin Oncol, 124, pp. 172-178.
19. Baker, DG, Sager, H., Constable, WC and Goodchild, NT (1984) Influence of ultrasound-induced hyperthermia and X-irradiation on the incidence of metastases from a solid tumor. Invasion Metastasis, 4, pp. 111-124.
20. Kampinga, HH (2006) Cell biological effects of hyperthermia alone or combined with radiation or drugs: A short introduction to newcomers in the field. Int J Hyperthermia, 22, pp. 191-196.
21. Peschke, P., Hahn, EW, Wenz, F., Lohr, F., Braunschweig, F., Wolber, G., Zuna, I. and Wannenmacher, M. (1998) Differential sensitivity of three sublines of the rat Dunning prostate tumor system R3327 to radiation and/ or local tumor hyperthermia. Radiat Res, 150, pp. 423-430.
22. Wondergem, J., Bulger, RE, Strebel, FR, Newman, RA, Travis, EL, Stephens, LC and Bull, JM (1988) Effect of cis-diamminedichloroplatinum(II) combined with whole body hyperthermia on renal injury. Cancer Res, 48, pp. 440-446.
23. Wondergem, J., Strebel, FR, Stephens, LC, Siddik, ZH and Bull, JM (1995) Chronic effect of whole body hyperthermia combined simultaneously with cis-diamminedichloroplatinum (II) on normal tissue in rat. Int J Hyperthermia, 11, pp. 37-47.
24. Wondergem, J., Bulger, RE, Siddik, ZH, Leygraaf, JW, Strebel, FR, Alonso, M., Travis, EL and Bull, JM (1989) A comparison of thermal enhancement of cis-diamminedichloroplatinum (II) induced renal and intestinal toxicities by whole body hyperthermia in the rat. Int J Radiat Oncol Biol Phys, 16, pp. 1551-1556.
25. Toyota, N., Strebel, FR, Stephens, LC, Matsuda, H. and Bull, JM (1997) Long-duration, mild whole body hyperthermia with cisplatin: Tumour response and kinetics of apoptosis and necrosis in a metastatic rat mammary adenocarcinoma. Int J Hyperthermia, 13, pp. 497-506.
26. Richel, O., Vrding, PJ Zum Vörde Sive, Rietbroek, R., Van der Velden, J., Van Dijk, JD, Schilthuis, MS and Westermann, AM (2004) Phase II study of carboplatin and whole body hyperthermia (WBH) in recurrent and metastatic cervical cancer. Gynecol Oncol, 95, pp. 680-685.
27. Ohno, S., Siddik, ZH, Baba, H., Stephens, LC, Strebel, FR, Wondergem, J., Khokhar, AR and Bull, JM (1991) Effect of carboplatin combined with whole body hyperthermia on normal tissue and tumor in rats. Cancer Res, 51, pp. 2994-3000.
28. Cohen, JD, Robins, HI, Tapazoglou, E., Schmitt, CL, Sapareto, SA and Khatana, A. (1991) Whole body hyperthermia and carboplatin: Cytotoxicity for murin leukaemia and normal marrow. Br J Cancer, 64, pp. 528-530.
29. Baba, H., Maehara, Y., Takeuchi, H., Inutsuka, S. and Sugimachi, K. (1993) Optimal scheduling increases therapeutic gain of adriamycin combined with hyperthermia. Anticancer Res, 13, pp. 651-654.
30. Wondergem, J., Stephens, LC, Strebel, FR, Baba, H., Ohno, S., Siddik, ZH, Newman, RA and Bull, JM (1991) Effect of adriamycin combined with whole body hyperthermia on tumor and normal tissues. Cancer Res, 51, pp. 3559-3567.
31. Kong, G., Braun, RD and Dewhirst, MW (2000) Hyperthermia enables tumor-specific nanoparticle delivery: Effect of particle size. Cancer Res, 60, pp. 4440-4445.
32. Kong, G., Braun, RD and Dewhirst, MW (2001) Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature. Cancer Res, 61, pp. 3027-3032.
33. Sakaguchi, Y., Stephens, L., Danhauser, L., Makino, M., Strebel, FR, Jenkins, GN and Bull, JMC (1993) Enhancement of antitumor effect and induction of apoptosis by a combination of 5-fluorouracil and whole body hyperthermia in rats. Proc Amer Assoc Cancer Res, 34, p. 361.
34. Haveman, J., Rietbroek, RC, Geerdink, A., van Rijn, J. and Bakker, PJl (1995) Effect of hyperthermia on the cytotoxicity of 2′,2′-difluorodeoxycytidine (gemcitabine) in cultured SW1573 cells. Int J Cancer, 62, pp. 627-630.
35. Mohamed, F., Marchettini, P., Stuart, OA, Urano, M. and Sugarbaker, PH (2003) Thermal enhancement of new chemotherapeutic agents at moderate hyperthermia. Ann Surg Oncol, 10, p. 463.
36. Katschinski, DM, Jacobson, EL, Wiedemann, GJ and Robins, HI (2001) Modulation of VP-16 cytotoxicity by carboplatin and 41.8°C hyperthermia. J Cancer Res Clin Oncol, 127, pp. 425-432.
37. Strebel, FR, Sumiyoshi, K., Jenkins, GN, Rowe, RW and Bull, JMC (2002) Drug sequence effect on therapeutic outcome (tumor growth, toxicity, and survival) of Irinotecan combined with Epirubicin in the in vivo MTLn3 rat mammary adenocarcinoma. Proc Amer Assoc Cancer Res, 43, p. 587.
38. Vertrees, RA, Das, GC, Popov, VL, Coscio, AM, Goodwin, TJ, Legrono, R., Zwischenberger, JB and Boor, PJ (2005) Synergistic interaction of hyperthermia and gemcitabine in lung cancer. Cancer Biol Ther, 4, pp. 1144-1153.
39. Van Moorsel, CJ, Pinedo, HM, Smid, K., Comijn, EM, Voorn, DA, Veerman, G., Lakerveld, B., Van der Vijgh, WJ, Giaccone, G., Postmus, PE and Peters, GJ (2000) Schedule-dependent pharmacodynamic effects of gemcitabine and cisplatin in mice bearing Lewis lung murine non-small cell lung tumours. Eur J Cancer, 36, pp. 2420-2429.
40. Kroep, JR, Peters, GJ, van Moorsel, CJA, Catik, A., Vermorken, JB, Pinedo, HM and van Groeningen, CJ (1999) Gemcitabine-cisplatin: A schedule finding study. Annals of Oncology, 10, pp. 1503-1510.
41. Ostberg, JR and Repasky, EA (2005) Emerging evidence indicates that physiologically relevant thermal stress regulates dendritic cell function. Cancer Immunol Immunother, 55, pp. 292-298.
42. Milani, V. and Noessner, E. (2005) Effects of thermal stress on tumor antigenicity and recognition by immune effector cells. Cancer Immunol Immunother, 55, pp. 312-319.