PLGA, chitosan or chitosan-coated PLGA microparticles for alveolar delivery?. A comparative study of particle stability during nebulization

Colloids and Surfaces B: Biointerfaces

Volumn 62, Issue 2, 2008, Pages 220-231

  Manca, Maria Letizia ^a,b   Mourtas, Spyridon ^a   Dracopoulos, Vassileios ^c   Fadda, Anna Maria ^b   Antimisiaris, Sophia G ^a,c  

^a UNIVERSITY OF PATRAS   (Greece)

^b UNIVERSITY OF CAGLIARI   (Italy)

^c INSTITUTE OF CHEMICAL ENGINEERING SCIENCES   (Greece)

Author keywords

Chitosan; Cytotoxicity; Encapsulation; Microparticle; Mucoadhesion; Nebulisation; PLGA; Rifampicin; Stability

Indexed keywords

CHITOSAN; CYTOTOXICITY; ENCAPSULATION; LIGHT SCATTERING; PRECIPITATION (CHEMICAL); SCANNING ELECTRON MICROSCOPY; SURFACE MORPHOLOGY; VISCOSITY;

ALVEOLAR DELIVERY; LIGHT SPECTROSCOPY; MICROPARTICLES; MUCOADHESION; NEBULIZATION; POLYLACTIDECOGLYCOLIDE; RIFAMPICINS;

DRUG DELIVERY;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CHITOSAN; CHITOSAN DERIVATIVE; GLUTARALDEHYDE; MUCIN; POLYGLACTIN; POLYMER;

ANALYTIC METHOD; ARTICLE; COMPARATIVE STUDY; CROSS LINKING; CYTOTOXICITY; EMULSION; ENCAPSULATION; EXTRACTION; FREEZE DRYING; LIGHT SCATTERING; NEBULIZATION; PRECIPITATION; PRIORITY JOURNAL; PROTEIN STABILITY; SCANNING ELECTRON MICROSCOPY; SPECTROSCOPY; VISCOSITY;

ADHESIVENESS; ADMINISTRATION, INHALATION; ANTIBIOTICS, ANTITUBERCULAR; CELL LINE; CHEMISTRY, PHYSICAL; CHITOSAN; DIFFUSION; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG STABILITY; ELECTROCHEMISTRY; EMULSIONS; HUMANS; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MOLECULAR WEIGHT; MUCINS; MUCOUS MEMBRANE; NEBULIZERS AND VAPORIZERS; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; PULMONARY ALVEOLI; RIFAMPIN; SOLVENTS; TETRAZOLIUM SALTS; THIAZOLES;

EID: 39449131163     PISSN: 09277765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2007.10.005     Document Type: Article

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