Exploiting glycogen synthase kinase 3β flexibility in molecular recognition

Biochemical Society Transactions

Volumn 36, Issue 1, 2008, Pages 55-58

  Mazanetz, Michael P ^a   Withers, Ian M ^a   Laughton, Charles A ^a   Fischer, Peter M ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Glycogen synthase kinase 3 ; Molecular dynamics; Molecular recognition; Protein flexibility; Quantitative structure activity relationship; Structure based drug design

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLYCOGEN SYNTHASE KINASE 3BETA; REGULATOR PROTEIN;

ALZHEIMER DISEASE; ARTICLE; DIABETES MELLITUS; ENZYME INHIBITION; MOLECULAR DOCKING; MOLECULAR RECOGNITION; PLASTICITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

COMPUTER SIMULATION; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INHIBITORY CONCENTRATION 50; LIGANDS; MODELS, MOLECULAR; PLIABILITY; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 39449125878     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0360055     Document Type: Article

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