-
1
-
-
8644280287
-
Tumor-activated prodrugs - a new approach to cancer therapy
-
Denny WA. Tumor-activated prodrugs - a new approach to cancer therapy. Cancer Invest 2004; 22: 604-619.
-
(2004)
Cancer Invest
, vol.22
, pp. 604-619
-
-
Denny, W.A.1
-
2
-
-
4444318140
-
Gene-directed enzyme prodrug therapy: A current assessment
-
McKeown SR, Ward C, Robson T. Gene-directed enzyme prodrug therapy: a current assessment. Curr Opin Mol Ther 2004; 6: 421-435.
-
(2004)
Curr Opin Mol Ther
, vol.6
, pp. 421-435
-
-
McKeown, S.R.1
Ward, C.2
Robson, T.3
-
3
-
-
33746859350
-
Novel gene-directed enzyme prodrug therapies against prostate cancer
-
Russell PJ, Khatri A. Novel gene-directed enzyme prodrug therapies against prostate cancer. Exp Opin Invest Drugs 2006; 15: 947-61.
-
(2006)
Exp Opin Invest Drugs
, vol.15
, pp. 947-961
-
-
Russell, P.J.1
Khatri, A.2
-
4
-
-
0035464156
-
Genetic reshuffling reconstitutes functional expression cassettes in retroviral vectors
-
Tabotta W, Klein D, Hohenadl C, et al. Genetic reshuffling reconstitutes functional expression cassettes in retroviral vectors. J Gene Med 2001; 3: 418-426.
-
(2001)
J Gene Med
, vol.3
, pp. 418-426
-
-
Tabotta, W.1
Klein, D.2
Hohenadl, C.3
-
5
-
-
25144441095
-
Effect of posttranscriptional regulatory elements on transgene expression and virus production in the context of retrovirus vectors
-
Hlavaty J, Schittmayer M, Stracke A, et al. Effect of posttranscriptional regulatory elements on transgene expression and virus production in the context of retrovirus vectors. Virology 2005; 341: 1-11.
-
(2005)
Virology
, vol.341
, pp. 1-11
-
-
Hlavaty, J.1
Schittmayer, M.2
Stracke, A.3
-
6
-
-
7444224045
-
Effects of sequences of prokaryotic origin on titer and transgene expression in retroviral vectors
-
Hlavaty J, Portsmouth D, Stracke A, et al. Effects of sequences of prokaryotic origin on titer and transgene expression in retroviral vectors. Virology 2004; 330: 351-360.
-
(2004)
Virology
, vol.330
, pp. 351-360
-
-
Hlavaty, J.1
Portsmouth, D.2
Stracke, A.3
-
7
-
-
0347003567
-
Multiple modifications allow high-titer production of retroviral vectors carrying heterologous regulatory elements
-
Hlavaty J, Stracke A, Klein D, et al. Multiple modifications allow high-titer production of retroviral vectors carrying heterologous regulatory elements. J Virol 2004; 78: 1384-1392.
-
(2004)
J Virol
, vol.78
, pp. 1384-1392
-
-
Hlavaty, J.1
Stracke, A.2
Klein, D.3
-
8
-
-
39449105688
-
New generations of retroviraI vector for safe, efficient and targeted gene therapy
-
Günzburg WH, Hlavaty J, Indik S, et al. New generations of retroviraI vector for safe, efficient and targeted gene therapy. Gene Ther Mol Biol 2006; 10: 185-192.
-
(2006)
Gene Ther Mol Biol
, vol.10
, pp. 185-192
-
-
Günzburg, W.H.1
Hlavaty, J.2
Indik, S.3
-
9
-
-
19944362199
-
A 470 bp WAP-promoter fragment confers lactation independent, progesterone regulated mammary-specific gene expression in transgenic mice
-
Lipnik K, Petznek H, Renner-Muller I, et al. A 470 bp WAP-promoter fragment confers lactation independent, progesterone regulated mammary-specific gene expression in transgenic mice. Transgenic Res 2005; 14: 145-158.
-
(2005)
Transgenic Res
, vol.14
, pp. 145-158
-
-
Lipnik, K.1
Petznek, H.2
Renner-Muller, I.3
-
10
-
-
33646517273
-
Hypoxia- and radiation-inducible, breast cell-specific targeting of retroviral vectors
-
Lipnik K, Greco O, Scott S, et al. Hypoxia- and radiation-inducible, breast cell-specific targeting of retroviral vectors. Virology 2006; 349: 121-133.
-
(2006)
Virology
, vol.349
, pp. 121-133
-
-
Lipnik, K.1
Greco, O.2
Scott, S.3
-
11
-
-
0036225415
-
The murine whey acidic protein promoter directs expression to human mammary tumors after retroviral transduction
-
Özturk-Winder F, Renner M, Klein D, et al. The murine whey acidic protein promoter directs expression to human mammary tumors after retroviral transduction. Cancer Gene Ther 2002; 9: 421-431.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 421-431
-
-
Özturk-Winder, F.1
Renner, M.2
Klein, D.3
-
12
-
-
2642670314
-
Construction and characterization of a hybrid mouse mammary tumor virus/murine leukemia virus-based retroviral vector
-
Saller RM, Özturk F, Salmons B, et al. Construction and characterization of a hybrid mouse mammary tumor virus/murine leukemia virus-based retroviral vector. J Virol 1998; 72: 1699-1703.
-
(1998)
J Virol
, vol.72
, pp. 1699-1703
-
-
Saller, R.M.1
Özturk, F.2
Salmons, B.3
-
13
-
-
32844457563
-
The cytotoxic activity of the bacteriophage lambda-holin protein reduces tumour growth rates in mammary cancer cell xenograft models
-
Agu CA, Klein I, Schwab S, et al. The cytotoxic activity of the bacteriophage lambda-holin protein reduces tumour growth rates in mammary cancer cell xenograft models. J Gene Med 2006; 8: 229-241.
-
(2006)
J Gene Med
, vol.8
, pp. 229-241
-
-
Agu, C.A.1
Klein, I.2
Schwab, S.3
-
14
-
-
0036293432
-
Specific packaging of spliced retroviral vector transcripts lacking the Psi-region
-
Pambalk K, Hohenadl C, Salmons B, et al. Specific packaging of spliced retroviral vector transcripts lacking the Psi-region. Biochem Biophys Res Commun 2002; 293: 239-246.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 239-246
-
-
Pambalk, K.1
Hohenadl, C.2
Salmons, B.3
-
15
-
-
0024520745
-
Site-directed mutagenesis by overlap extension using the polymerase chain reaction
-
Ho SN, Hunt HD, Horton RM, et al. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 1989; 77: 51-59.
-
(1989)
Gene
, vol.77
, pp. 51-59
-
-
Ho, S.N.1
Hunt, H.D.2
Horton, R.M.3
-
16
-
-
0021930843
-
Production of mouse mammary tumor virus upon transfection of a recombinant proviral DNA into cultured cells
-
Salmons B, Groner B, Calberg-Bacq CM, et al. Production of mouse mammary tumor virus upon transfection of a recombinant proviral DNA into cultured cells. Virology 1985; 144: 101-114.
-
(1985)
Virology
, vol.144
, pp. 101-114
-
-
Salmons, B.1
Groner, B.2
Calberg-Bacq, C.M.3
-
17
-
-
0015044799
-
Involvement of recombination genes in growth and viability ofEscherichia coli K-12
-
Capaldo-Kimball F, Barbour SD. Involvement of recombination genes in growth and viability ofEscherichia coli K-12. J Bacteriol 1971; 106: 204-212.
-
(1971)
J Bacteriol
, vol.106
, pp. 204-212
-
-
Capaldo-Kimball, F.1
Barbour, S.D.2
-
18
-
-
0037448618
-
An Escherichia coli strain, BJ5183, that shows highly efficient conservative (two-progeny) DNA double-strand break repair of restriction breaks
-
Takahashi N, Yoshikura H, Kobayashi I. An Escherichia coli strain, BJ5183, that shows highly efficient conservative (two-progeny) DNA double-strand break repair of restriction breaks. Gene 2003; 303: 89-97.
-
(2003)
Gene
, vol.303
, pp. 89-97
-
-
Takahashi, N.1
Yoshikura, H.2
Kobayashi, I.3
-
19
-
-
0027324235
-
Rapid cloning by homologous recombination in vivo
-
Bubeck P, Winkler M, Bautsch W. Rapid cloning by homologous recombination in vivo. Nucleic Acids Res 1993; 21: 3601-3602.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 3601-3602
-
-
Bubeck, P.1
Winkler, M.2
Bautsch, W.3
-
20
-
-
0029977774
-
Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli
-
Chartier C, Degryse E, Gantzer M, et al. Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli. J Virol 1996; 70: 4805-4810.
-
(1996)
J Virol
, vol.70
, pp. 4805-4810
-
-
Chartier, C.1
Degryse, E.2
Gantzer, M.3
-
21
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
22
-
-
0019723823
-
Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences
-
Lusky M, Botchan M. Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences. Nature 1981; 293: 79-81.
-
(1981)
Nature
, vol.293
, pp. 79-81
-
-
Lusky, M.1
Botchan, M.2
-
23
-
-
0031950572
-
Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element
-
Donello JE, Loeb JE, Hope TJ. Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element. J Virol 1998; 72: 5085-5092.
-
(1998)
J Virol
, vol.72
, pp. 5085-5092
-
-
Donello, J.E.1
Loeb, J.E.2
Hope, T.J.3
-
24
-
-
0034003832
-
Deletion of a short, untranslated region adjacent to the polypurine tract in Moloney murine leukemia virus leads to formation of aberrant 5′ plusstrand DNA ends in vivo
-
Bacharach E, Gonsky J, Lim D, et al. Deletion of a short, untranslated region adjacent to the polypurine tract in Moloney murine leukemia virus leads to formation of aberrant 5′ plusstrand DNA ends in vivo. J Virol 2000; 74: 4755-4764.
-
(2000)
J Virol
, vol.74
, pp. 4755-4764
-
-
Bacharach, E.1
Gonsky, J.2
Lim, D.3
-
25
-
-
0031039590
-
Determination of the site of first strand transfer during Moloney murine leukemia virus reverse transcription and identification of strand transfer-associated reverse transcriptase errors
-
Kulpa D, Topping R, Telesnitsky A. Determination of the site of first strand transfer during Moloney murine leukemia virus reverse transcription and identification of strand transfer-associated reverse transcriptase errors. EMBO J 1997; 16: 856-865.
-
(1997)
EMBO J
, vol.16
, pp. 856-865
-
-
Kulpa, D.1
Topping, R.2
Telesnitsky, A.3
-
26
-
-
0033760885
-
Selection of optimal polypurine tract region sequences during Moloney murine leukemia virus replication
-
Robson ND, Telesnitsky A. Selection of optimal polypurine tract region sequences during Moloney murine leukemia virus replication. J Virol 2000; 74: 10293-10303.
-
(2000)
J Virol
, vol.74
, pp. 10293-10303
-
-
Robson, N.D.1
Telesnitsky, A.2
-
27
-
-
0033857834
-
The 17 nucleotides downstream from the env gene stop codon are important for murine leukemia virus packaging
-
Yu SS, Kim JM, Kim S. The 17 nucleotides downstream from the env gene stop codon are important for murine leukemia virus packaging. J Virol 2000; 74: 8775-8780.
-
(2000)
J Virol
, vol.74
, pp. 8775-8780
-
-
Yu, S.S.1
Kim, J.M.2
Kim, S.3
-
28
-
-
27644541955
-
Abundant authentic MMTV-Env production from a recombinant provirus lacking the major LTR promoter
-
Rungaldier S, Nejad Asl SB, Günzburg WH, et al. Abundant authentic MMTV-Env production from a recombinant provirus lacking the major LTR promoter. Virology 2005; 342: 201-214.
-
(2005)
Virology
, vol.342
, pp. 201-214
-
-
Rungaldier, S.1
Nejad Asl, S.B.2
Günzburg, W.H.3
-
29
-
-
0029056909
-
Extracellular matrix regulates whey acidic protein gene expression by suppression of TGF-alpha in mouse mammary epithelial cells: Studies in culture and in transgenic mice
-
Lin CQ, Dempsey PJ, Coffey RJ, et al. Extracellular matrix regulates whey acidic protein gene expression by suppression of TGF-alpha in mouse mammary epithelial cells: studies in culture and in transgenic mice. J Cell Biol 1995; 129: 1115-1126.
-
(1995)
J Cell Biol
, vol.129
, pp. 1115-1126
-
-
Lin, C.Q.1
Dempsey, P.J.2
Coffey, R.J.3
-
30
-
-
0025359498
-
Induction of the endogenous whey acidic protein (Wap) gene and a Wap-myc hybrid gene in primary murine mammary organoids
-
Schoenenberger CA, Zuk A, Groner B, et al. Induction of the endogenous whey acidic protein (Wap) gene and a Wap-myc hybrid gene in primary murine mammary organoids. Dev Biol 1990; 139: 327-337.
-
(1990)
Dev Biol
, vol.139
, pp. 327-337
-
-
Schoenenberger, C.A.1
Zuk, A.2
Groner, B.3
-
31
-
-
0034322479
-
Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors
-
Schambach A, Wodrich H, Hildinger M. et al. Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors. Mol Ther 2000; 2: 435-445.
-
(2000)
Mol Ther
, vol.2
, pp. 435-445
-
-
Schambach, A.1
Wodrich, H.2
Hildinger, M.3
-
32
-
-
33645103149
-
Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression
-
Schambach A, Bohne J. Baum C, et al. Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression. Gene Ther 2006; 13: 641-645.
-
(2006)
Gene Ther
, vol.13
, pp. 641-645
-
-
Schambach, A.1
Bohne, J.2
Baum, C.3
-
33
-
-
0032978712
-
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
-
Zufferey R. Donello JE, Trono D, et al. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J Virol 1999; 73: 2886-2892.
-
(1999)
J Virol
, vol.73
, pp. 2886-2892
-
-
Zufferey, R.1
Donello, J.E.2
Trono, D.3
-
34
-
-
33646051851
-
WPRE-mediated enhancement of gene expression is promoter and cell line specific
-
Klein R, Ruttkowski B, Knapp E, et al. WPRE-mediated enhancement of gene expression is promoter and cell line specific. Gene 2006; 372: 153-161.
-
(2006)
Gene
, vol.372
, pp. 153-161
-
-
Klein, R.1
Ruttkowski, B.2
Knapp, E.3
-
35
-
-
0036121419
-
CRM1-dependent function of a cis-acting RNA export element
-
Popa I, Harris ME, Donello JE, et al. CRM1-dependent function of a cis-acting RNA export element. Mol Cell Biol 2002; 22: 2057-2067.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2057-2067
-
-
Popa, I.1
Harris, M.E.2
Donello, J.E.3
-
36
-
-
0025861696
-
Overlapping retrovirus US sequence elements are required for efficient integration and initiation of reverse transcription
-
Cobrinik D, Aiyar A, Ge Z, et al. Overlapping retrovirus US sequence elements are required for efficient integration and initiation of reverse transcription. J Virol 1991; 65: 3864-3872.
-
(1991)
J Virol
, vol.65
, pp. 3864-3872
-
-
Cobrinik, D.1
Aiyar, A.2
Ge, Z.3
-
37
-
-
0024548408
-
Construction and analysis of deletion mutations in the US region of Moloney murine leukemia virus: Effects on RNA packaging and reverse transcription
-
Murphy JE, Goff SP. Construction and analysis of deletion mutations in the US region of Moloney murine leukemia virus: effects on RNA packaging and reverse transcription. J Virol 1989; 63:319-327.
-
(1989)
J Virol
, vol.63
, pp. 319-327
-
-
Murphy, J.E.1
Goff, S.P.2
-
38
-
-
38649109441
-
Quantification and characterization of autotransduction in retrovirus producer cells
-
DOI:10.1089/hum.2007.071
-
Brandtner E-M, Kodajova P, Knapp E, et al. Quantification and characterization of autotransduction in retrovirus producer cells. Hum Gene Ther 19; 2008: DOI:10.1089/hum.2007.071.
-
(2008)
Hum Gene Ther
, vol.19
-
-
Brandtner, E.-M.1
Kodajova, P.2
Knapp, E.3
-
39
-
-
0032883091
-
Retrovirus vectors designed for efficient transduction of cytotoxic or cytostatic genes
-
Ui M, Takada M. Arai T, et al. Retrovirus vectors designed for efficient transduction of cytotoxic or cytostatic genes. Gene Ther 1999; 6: 1670-1678.
-
(1999)
Gene Ther
, vol.6
, pp. 1670-1678
-
-
Ui, M.1
Takada, M.2
Arai, T.3
-
40
-
-
0033759150
-
A lentiviral vector expressing a fusogenic glycoprotein for cancer gene therapy
-
Diaz RM, Bateman A, Emiliusen L, et al. A lentiviral vector expressing a fusogenic glycoprotein for cancer gene therapy. Gene Ther 2000; 7: 1656-1663.
-
(2000)
Gene Ther
, vol.7
, pp. 1656-1663
-
-
Diaz, R.M.1
Bateman, A.2
Emiliusen, L.3
-
41
-
-
0036631908
-
PG13 packaging cells produce recombinant retroviruses carrying a diphtheria toxin mutant which kills cancer cells
-
Qiao J, Caruso M. PG13 packaging cells produce recombinant retroviruses carrying a diphtheria toxin mutant which kills cancer cells. J Virol 2002; 76: 7343-7348.
-
(2002)
J Virol
, vol.76
, pp. 7343-7348
-
-
Qiao, J.1
Caruso, M.2
-
42
-
-
3042734229
-
Development of a self-inactivating tet-on retroviral vector expressing bone morphogenetic protein 4 to achieve regulated bone formation
-
Peng H, Usas A, Gearhart B, et al. Development of a self-inactivating tet-on retroviral vector expressing bone morphogenetic protein 4 to achieve regulated bone formation. Mol Ther 2004; 9: 885-894.
-
(2004)
Mol Ther
, vol.9
, pp. 885-894
-
-
Peng, H.1
Usas, A.2
Gearhart, B.3
-
43
-
-
21044449615
-
Tight control of transgene expression by lentivirus vectors containing second-generation tetracycline-responsive promoters
-
Pluta K, Luce MJ, Bao L, et al. Tight control of transgene expression by lentivirus vectors containing second-generation tetracycline-responsive promoters. J Gene Med 2005; 7: 803-817.
-
(2005)
J Gene Med
, vol.7
, pp. 803-817
-
-
Pluta, K.1
Luce, M.J.2
Bao, L.3
-
44
-
-
4444270959
-
Encapsulated, genetically modified cells producing in vivo therapeutics
-
Hauser O, Prieschl-Grassauer E, Salmons B. Encapsulated, genetically modified cells producing in vivo therapeutics. Curr Opin Mol Ther 2004; 6: 412-420.
-
(2004)
Curr Opin Mol Ther
, vol.6
, pp. 412-420
-
-
Hauser, O.1
Prieschl-Grassauer, E.2
Salmons, B.3
-
45
-
-
0036518340
-
Encapsulated cells producing retroviral vectors for in vivo gene transfer
-
Saller RM, Indraccolo S, Coppola V, et al. Encapsulated cells producing retroviral vectors for in vivo gene transfer. J Gene Med 2002; 4: 150-160.
-
(2002)
J Gene Med
, vol.4
, pp. 150-160
-
-
Saller, R.M.1
Indraccolo, S.2
Coppola, V.3
|