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Volumn 10, Issue 2, 2008, Pages 113-122

Reconstituting retroviral (ReCon) vectors facilitating delivery of cytotoxic genes in cancer gene therapy approaches

Author keywords

Cancer gene therapy; Cytotoxic gene; Expression targeting; Retroviral vector; Vector optimization

Indexed keywords

ACID PROTEIN; ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; LAMBDA HOLIN; RETROVIRUS VECTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 39449107788     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1143     Document Type: Article
Times cited : (8)

References (45)
  • 1
    • 8644280287 scopus 로고    scopus 로고
    • Tumor-activated prodrugs - a new approach to cancer therapy
    • Denny WA. Tumor-activated prodrugs - a new approach to cancer therapy. Cancer Invest 2004; 22: 604-619.
    • (2004) Cancer Invest , vol.22 , pp. 604-619
    • Denny, W.A.1
  • 2
    • 4444318140 scopus 로고    scopus 로고
    • Gene-directed enzyme prodrug therapy: A current assessment
    • McKeown SR, Ward C, Robson T. Gene-directed enzyme prodrug therapy: a current assessment. Curr Opin Mol Ther 2004; 6: 421-435.
    • (2004) Curr Opin Mol Ther , vol.6 , pp. 421-435
    • McKeown, S.R.1    Ward, C.2    Robson, T.3
  • 3
    • 33746859350 scopus 로고    scopus 로고
    • Novel gene-directed enzyme prodrug therapies against prostate cancer
    • Russell PJ, Khatri A. Novel gene-directed enzyme prodrug therapies against prostate cancer. Exp Opin Invest Drugs 2006; 15: 947-61.
    • (2006) Exp Opin Invest Drugs , vol.15 , pp. 947-961
    • Russell, P.J.1    Khatri, A.2
  • 4
    • 0035464156 scopus 로고    scopus 로고
    • Genetic reshuffling reconstitutes functional expression cassettes in retroviral vectors
    • Tabotta W, Klein D, Hohenadl C, et al. Genetic reshuffling reconstitutes functional expression cassettes in retroviral vectors. J Gene Med 2001; 3: 418-426.
    • (2001) J Gene Med , vol.3 , pp. 418-426
    • Tabotta, W.1    Klein, D.2    Hohenadl, C.3
  • 5
    • 25144441095 scopus 로고    scopus 로고
    • Effect of posttranscriptional regulatory elements on transgene expression and virus production in the context of retrovirus vectors
    • Hlavaty J, Schittmayer M, Stracke A, et al. Effect of posttranscriptional regulatory elements on transgene expression and virus production in the context of retrovirus vectors. Virology 2005; 341: 1-11.
    • (2005) Virology , vol.341 , pp. 1-11
    • Hlavaty, J.1    Schittmayer, M.2    Stracke, A.3
  • 6
    • 7444224045 scopus 로고    scopus 로고
    • Effects of sequences of prokaryotic origin on titer and transgene expression in retroviral vectors
    • Hlavaty J, Portsmouth D, Stracke A, et al. Effects of sequences of prokaryotic origin on titer and transgene expression in retroviral vectors. Virology 2004; 330: 351-360.
    • (2004) Virology , vol.330 , pp. 351-360
    • Hlavaty, J.1    Portsmouth, D.2    Stracke, A.3
  • 7
    • 0347003567 scopus 로고    scopus 로고
    • Multiple modifications allow high-titer production of retroviral vectors carrying heterologous regulatory elements
    • Hlavaty J, Stracke A, Klein D, et al. Multiple modifications allow high-titer production of retroviral vectors carrying heterologous regulatory elements. J Virol 2004; 78: 1384-1392.
    • (2004) J Virol , vol.78 , pp. 1384-1392
    • Hlavaty, J.1    Stracke, A.2    Klein, D.3
  • 8
    • 39449105688 scopus 로고    scopus 로고
    • New generations of retroviraI vector for safe, efficient and targeted gene therapy
    • Günzburg WH, Hlavaty J, Indik S, et al. New generations of retroviraI vector for safe, efficient and targeted gene therapy. Gene Ther Mol Biol 2006; 10: 185-192.
    • (2006) Gene Ther Mol Biol , vol.10 , pp. 185-192
    • Günzburg, W.H.1    Hlavaty, J.2    Indik, S.3
  • 9
    • 19944362199 scopus 로고    scopus 로고
    • A 470 bp WAP-promoter fragment confers lactation independent, progesterone regulated mammary-specific gene expression in transgenic mice
    • Lipnik K, Petznek H, Renner-Muller I, et al. A 470 bp WAP-promoter fragment confers lactation independent, progesterone regulated mammary-specific gene expression in transgenic mice. Transgenic Res 2005; 14: 145-158.
    • (2005) Transgenic Res , vol.14 , pp. 145-158
    • Lipnik, K.1    Petznek, H.2    Renner-Muller, I.3
  • 10
    • 33646517273 scopus 로고    scopus 로고
    • Hypoxia- and radiation-inducible, breast cell-specific targeting of retroviral vectors
    • Lipnik K, Greco O, Scott S, et al. Hypoxia- and radiation-inducible, breast cell-specific targeting of retroviral vectors. Virology 2006; 349: 121-133.
    • (2006) Virology , vol.349 , pp. 121-133
    • Lipnik, K.1    Greco, O.2    Scott, S.3
  • 11
    • 0036225415 scopus 로고    scopus 로고
    • The murine whey acidic protein promoter directs expression to human mammary tumors after retroviral transduction
    • Özturk-Winder F, Renner M, Klein D, et al. The murine whey acidic protein promoter directs expression to human mammary tumors after retroviral transduction. Cancer Gene Ther 2002; 9: 421-431.
    • (2002) Cancer Gene Ther , vol.9 , pp. 421-431
    • Özturk-Winder, F.1    Renner, M.2    Klein, D.3
  • 12
    • 2642670314 scopus 로고    scopus 로고
    • Construction and characterization of a hybrid mouse mammary tumor virus/murine leukemia virus-based retroviral vector
    • Saller RM, Özturk F, Salmons B, et al. Construction and characterization of a hybrid mouse mammary tumor virus/murine leukemia virus-based retroviral vector. J Virol 1998; 72: 1699-1703.
    • (1998) J Virol , vol.72 , pp. 1699-1703
    • Saller, R.M.1    Özturk, F.2    Salmons, B.3
  • 13
    • 32844457563 scopus 로고    scopus 로고
    • The cytotoxic activity of the bacteriophage lambda-holin protein reduces tumour growth rates in mammary cancer cell xenograft models
    • Agu CA, Klein I, Schwab S, et al. The cytotoxic activity of the bacteriophage lambda-holin protein reduces tumour growth rates in mammary cancer cell xenograft models. J Gene Med 2006; 8: 229-241.
    • (2006) J Gene Med , vol.8 , pp. 229-241
    • Agu, C.A.1    Klein, I.2    Schwab, S.3
  • 14
    • 0036293432 scopus 로고    scopus 로고
    • Specific packaging of spliced retroviral vector transcripts lacking the Psi-region
    • Pambalk K, Hohenadl C, Salmons B, et al. Specific packaging of spliced retroviral vector transcripts lacking the Psi-region. Biochem Biophys Res Commun 2002; 293: 239-246.
    • (2002) Biochem Biophys Res Commun , vol.293 , pp. 239-246
    • Pambalk, K.1    Hohenadl, C.2    Salmons, B.3
  • 15
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho SN, Hunt HD, Horton RM, et al. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 1989; 77: 51-59.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3
  • 16
    • 0021930843 scopus 로고
    • Production of mouse mammary tumor virus upon transfection of a recombinant proviral DNA into cultured cells
    • Salmons B, Groner B, Calberg-Bacq CM, et al. Production of mouse mammary tumor virus upon transfection of a recombinant proviral DNA into cultured cells. Virology 1985; 144: 101-114.
    • (1985) Virology , vol.144 , pp. 101-114
    • Salmons, B.1    Groner, B.2    Calberg-Bacq, C.M.3
  • 17
    • 0015044799 scopus 로고
    • Involvement of recombination genes in growth and viability ofEscherichia coli K-12
    • Capaldo-Kimball F, Barbour SD. Involvement of recombination genes in growth and viability ofEscherichia coli K-12. J Bacteriol 1971; 106: 204-212.
    • (1971) J Bacteriol , vol.106 , pp. 204-212
    • Capaldo-Kimball, F.1    Barbour, S.D.2
  • 18
    • 0037448618 scopus 로고    scopus 로고
    • An Escherichia coli strain, BJ5183, that shows highly efficient conservative (two-progeny) DNA double-strand break repair of restriction breaks
    • Takahashi N, Yoshikura H, Kobayashi I. An Escherichia coli strain, BJ5183, that shows highly efficient conservative (two-progeny) DNA double-strand break repair of restriction breaks. Gene 2003; 303: 89-97.
    • (2003) Gene , vol.303 , pp. 89-97
    • Takahashi, N.1    Yoshikura, H.2    Kobayashi, I.3
  • 19
    • 0027324235 scopus 로고
    • Rapid cloning by homologous recombination in vivo
    • Bubeck P, Winkler M, Bautsch W. Rapid cloning by homologous recombination in vivo. Nucleic Acids Res 1993; 21: 3601-3602.
    • (1993) Nucleic Acids Res , vol.21 , pp. 3601-3602
    • Bubeck, P.1    Winkler, M.2    Bautsch, W.3
  • 20
    • 0029977774 scopus 로고    scopus 로고
    • Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli
    • Chartier C, Degryse E, Gantzer M, et al. Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli. J Virol 1996; 70: 4805-4810.
    • (1996) J Virol , vol.70 , pp. 4805-4810
    • Chartier, C.1    Degryse, E.2    Gantzer, M.3
  • 21
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 22
    • 0019723823 scopus 로고
    • Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences
    • Lusky M, Botchan M. Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences. Nature 1981; 293: 79-81.
    • (1981) Nature , vol.293 , pp. 79-81
    • Lusky, M.1    Botchan, M.2
  • 23
    • 0031950572 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element
    • Donello JE, Loeb JE, Hope TJ. Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element. J Virol 1998; 72: 5085-5092.
    • (1998) J Virol , vol.72 , pp. 5085-5092
    • Donello, J.E.1    Loeb, J.E.2    Hope, T.J.3
  • 24
    • 0034003832 scopus 로고    scopus 로고
    • Deletion of a short, untranslated region adjacent to the polypurine tract in Moloney murine leukemia virus leads to formation of aberrant 5′ plusstrand DNA ends in vivo
    • Bacharach E, Gonsky J, Lim D, et al. Deletion of a short, untranslated region adjacent to the polypurine tract in Moloney murine leukemia virus leads to formation of aberrant 5′ plusstrand DNA ends in vivo. J Virol 2000; 74: 4755-4764.
    • (2000) J Virol , vol.74 , pp. 4755-4764
    • Bacharach, E.1    Gonsky, J.2    Lim, D.3
  • 25
    • 0031039590 scopus 로고    scopus 로고
    • Determination of the site of first strand transfer during Moloney murine leukemia virus reverse transcription and identification of strand transfer-associated reverse transcriptase errors
    • Kulpa D, Topping R, Telesnitsky A. Determination of the site of first strand transfer during Moloney murine leukemia virus reverse transcription and identification of strand transfer-associated reverse transcriptase errors. EMBO J 1997; 16: 856-865.
    • (1997) EMBO J , vol.16 , pp. 856-865
    • Kulpa, D.1    Topping, R.2    Telesnitsky, A.3
  • 26
    • 0033760885 scopus 로고    scopus 로고
    • Selection of optimal polypurine tract region sequences during Moloney murine leukemia virus replication
    • Robson ND, Telesnitsky A. Selection of optimal polypurine tract region sequences during Moloney murine leukemia virus replication. J Virol 2000; 74: 10293-10303.
    • (2000) J Virol , vol.74 , pp. 10293-10303
    • Robson, N.D.1    Telesnitsky, A.2
  • 27
    • 0033857834 scopus 로고    scopus 로고
    • The 17 nucleotides downstream from the env gene stop codon are important for murine leukemia virus packaging
    • Yu SS, Kim JM, Kim S. The 17 nucleotides downstream from the env gene stop codon are important for murine leukemia virus packaging. J Virol 2000; 74: 8775-8780.
    • (2000) J Virol , vol.74 , pp. 8775-8780
    • Yu, S.S.1    Kim, J.M.2    Kim, S.3
  • 28
    • 27644541955 scopus 로고    scopus 로고
    • Abundant authentic MMTV-Env production from a recombinant provirus lacking the major LTR promoter
    • Rungaldier S, Nejad Asl SB, Günzburg WH, et al. Abundant authentic MMTV-Env production from a recombinant provirus lacking the major LTR promoter. Virology 2005; 342: 201-214.
    • (2005) Virology , vol.342 , pp. 201-214
    • Rungaldier, S.1    Nejad Asl, S.B.2    Günzburg, W.H.3
  • 29
    • 0029056909 scopus 로고
    • Extracellular matrix regulates whey acidic protein gene expression by suppression of TGF-alpha in mouse mammary epithelial cells: Studies in culture and in transgenic mice
    • Lin CQ, Dempsey PJ, Coffey RJ, et al. Extracellular matrix regulates whey acidic protein gene expression by suppression of TGF-alpha in mouse mammary epithelial cells: studies in culture and in transgenic mice. J Cell Biol 1995; 129: 1115-1126.
    • (1995) J Cell Biol , vol.129 , pp. 1115-1126
    • Lin, C.Q.1    Dempsey, P.J.2    Coffey, R.J.3
  • 30
    • 0025359498 scopus 로고
    • Induction of the endogenous whey acidic protein (Wap) gene and a Wap-myc hybrid gene in primary murine mammary organoids
    • Schoenenberger CA, Zuk A, Groner B, et al. Induction of the endogenous whey acidic protein (Wap) gene and a Wap-myc hybrid gene in primary murine mammary organoids. Dev Biol 1990; 139: 327-337.
    • (1990) Dev Biol , vol.139 , pp. 327-337
    • Schoenenberger, C.A.1    Zuk, A.2    Groner, B.3
  • 31
    • 0034322479 scopus 로고    scopus 로고
    • Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors
    • Schambach A, Wodrich H, Hildinger M. et al. Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors. Mol Ther 2000; 2: 435-445.
    • (2000) Mol Ther , vol.2 , pp. 435-445
    • Schambach, A.1    Wodrich, H.2    Hildinger, M.3
  • 32
    • 33645103149 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression
    • Schambach A, Bohne J. Baum C, et al. Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression. Gene Ther 2006; 13: 641-645.
    • (2006) Gene Ther , vol.13 , pp. 641-645
    • Schambach, A.1    Bohne, J.2    Baum, C.3
  • 33
    • 0032978712 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
    • Zufferey R. Donello JE, Trono D, et al. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J Virol 1999; 73: 2886-2892.
    • (1999) J Virol , vol.73 , pp. 2886-2892
    • Zufferey, R.1    Donello, J.E.2    Trono, D.3
  • 34
    • 33646051851 scopus 로고    scopus 로고
    • WPRE-mediated enhancement of gene expression is promoter and cell line specific
    • Klein R, Ruttkowski B, Knapp E, et al. WPRE-mediated enhancement of gene expression is promoter and cell line specific. Gene 2006; 372: 153-161.
    • (2006) Gene , vol.372 , pp. 153-161
    • Klein, R.1    Ruttkowski, B.2    Knapp, E.3
  • 35
    • 0036121419 scopus 로고    scopus 로고
    • CRM1-dependent function of a cis-acting RNA export element
    • Popa I, Harris ME, Donello JE, et al. CRM1-dependent function of a cis-acting RNA export element. Mol Cell Biol 2002; 22: 2057-2067.
    • (2002) Mol Cell Biol , vol.22 , pp. 2057-2067
    • Popa, I.1    Harris, M.E.2    Donello, J.E.3
  • 36
    • 0025861696 scopus 로고
    • Overlapping retrovirus US sequence elements are required for efficient integration and initiation of reverse transcription
    • Cobrinik D, Aiyar A, Ge Z, et al. Overlapping retrovirus US sequence elements are required for efficient integration and initiation of reverse transcription. J Virol 1991; 65: 3864-3872.
    • (1991) J Virol , vol.65 , pp. 3864-3872
    • Cobrinik, D.1    Aiyar, A.2    Ge, Z.3
  • 37
    • 0024548408 scopus 로고
    • Construction and analysis of deletion mutations in the US region of Moloney murine leukemia virus: Effects on RNA packaging and reverse transcription
    • Murphy JE, Goff SP. Construction and analysis of deletion mutations in the US region of Moloney murine leukemia virus: effects on RNA packaging and reverse transcription. J Virol 1989; 63:319-327.
    • (1989) J Virol , vol.63 , pp. 319-327
    • Murphy, J.E.1    Goff, S.P.2
  • 38
    • 38649109441 scopus 로고    scopus 로고
    • Quantification and characterization of autotransduction in retrovirus producer cells
    • DOI:10.1089/hum.2007.071
    • Brandtner E-M, Kodajova P, Knapp E, et al. Quantification and characterization of autotransduction in retrovirus producer cells. Hum Gene Ther 19; 2008: DOI:10.1089/hum.2007.071.
    • (2008) Hum Gene Ther , vol.19
    • Brandtner, E.-M.1    Kodajova, P.2    Knapp, E.3
  • 39
    • 0032883091 scopus 로고    scopus 로고
    • Retrovirus vectors designed for efficient transduction of cytotoxic or cytostatic genes
    • Ui M, Takada M. Arai T, et al. Retrovirus vectors designed for efficient transduction of cytotoxic or cytostatic genes. Gene Ther 1999; 6: 1670-1678.
    • (1999) Gene Ther , vol.6 , pp. 1670-1678
    • Ui, M.1    Takada, M.2    Arai, T.3
  • 40
    • 0033759150 scopus 로고    scopus 로고
    • A lentiviral vector expressing a fusogenic glycoprotein for cancer gene therapy
    • Diaz RM, Bateman A, Emiliusen L, et al. A lentiviral vector expressing a fusogenic glycoprotein for cancer gene therapy. Gene Ther 2000; 7: 1656-1663.
    • (2000) Gene Ther , vol.7 , pp. 1656-1663
    • Diaz, R.M.1    Bateman, A.2    Emiliusen, L.3
  • 41
    • 0036631908 scopus 로고    scopus 로고
    • PG13 packaging cells produce recombinant retroviruses carrying a diphtheria toxin mutant which kills cancer cells
    • Qiao J, Caruso M. PG13 packaging cells produce recombinant retroviruses carrying a diphtheria toxin mutant which kills cancer cells. J Virol 2002; 76: 7343-7348.
    • (2002) J Virol , vol.76 , pp. 7343-7348
    • Qiao, J.1    Caruso, M.2
  • 42
    • 3042734229 scopus 로고    scopus 로고
    • Development of a self-inactivating tet-on retroviral vector expressing bone morphogenetic protein 4 to achieve regulated bone formation
    • Peng H, Usas A, Gearhart B, et al. Development of a self-inactivating tet-on retroviral vector expressing bone morphogenetic protein 4 to achieve regulated bone formation. Mol Ther 2004; 9: 885-894.
    • (2004) Mol Ther , vol.9 , pp. 885-894
    • Peng, H.1    Usas, A.2    Gearhart, B.3
  • 43
    • 21044449615 scopus 로고    scopus 로고
    • Tight control of transgene expression by lentivirus vectors containing second-generation tetracycline-responsive promoters
    • Pluta K, Luce MJ, Bao L, et al. Tight control of transgene expression by lentivirus vectors containing second-generation tetracycline-responsive promoters. J Gene Med 2005; 7: 803-817.
    • (2005) J Gene Med , vol.7 , pp. 803-817
    • Pluta, K.1    Luce, M.J.2    Bao, L.3
  • 44
    • 4444270959 scopus 로고    scopus 로고
    • Encapsulated, genetically modified cells producing in vivo therapeutics
    • Hauser O, Prieschl-Grassauer E, Salmons B. Encapsulated, genetically modified cells producing in vivo therapeutics. Curr Opin Mol Ther 2004; 6: 412-420.
    • (2004) Curr Opin Mol Ther , vol.6 , pp. 412-420
    • Hauser, O.1    Prieschl-Grassauer, E.2    Salmons, B.3
  • 45
    • 0036518340 scopus 로고    scopus 로고
    • Encapsulated cells producing retroviral vectors for in vivo gene transfer
    • Saller RM, Indraccolo S, Coppola V, et al. Encapsulated cells producing retroviral vectors for in vivo gene transfer. J Gene Med 2002; 4: 150-160.
    • (2002) J Gene Med , vol.4 , pp. 150-160
    • Saller, R.M.1    Indraccolo, S.2    Coppola, V.3


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