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Volumn 24, Issue 3, 2008, Pages 613-616

Poly-2-methyl-2-oxazoline: A peptide-like polymer for protein-repellent surfaces

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN-REPELLENT SURFACES; SIDE-CHAIN GRAFTING DENSITY; SURFACE COATINGS;

EID: 39449102648     PISSN: 07437463     EISSN: None     Source Type: Journal    
DOI: 10.1021/la702917z     Document Type: Article
Times cited : (298)

References (31)
  • 22
    • 0029059507 scopus 로고    scopus 로고
    • Miller, S. M.; Simon.R. J.; Ng, S.; Zuckermann, R. N.; Kerr, J. M.;Moos, W. H. Drug Dev. Res. 1995, 35, 20-32.
    • Miller, S. M.; Simon.R. J.; Ng, S.; Zuckermann, R. N.; Kerr, J. M.;Moos, W. H. Drug Dev. Res. 1995, 35, 20-32.
  • 29
    • 39449128395 scopus 로고    scopus 로고
    • PLL and PMOXA, because of their structural similarity, differ only in some peak component concentration ratios but do not exhibit characteristic peaks that would be unique for only one of them. Therefore, the contribution of the PLL backbone has been neglected in the calculations. The error introduced by this assumption is comparatively small, given that the PLL backbone for the used architecture accounts for only a small atomic percentage (13.9 % N and C and 7.5 % O). Furthermore, contributions stemming from contamination or surfacehydroxyl/water were also neglected.
    • PLL and PMOXA, because of their structural similarity, differ only in some peak component concentration ratios but do not exhibit characteristic peaks that would be unique for only one of them. Therefore, the contribution of the PLL backbone has been neglected in the calculations. The error introduced by this assumption is comparatively small, given that the PLL backbone for the used architecture accounts for only a small atomic percentage (13.9 % N and C and 7.5 % O). Furthermore, contributions stemming from contamination or surfacehydroxyl/water were also neglected.
  • 30
    • 39449083373 scopus 로고    scopus 로고
    • At very high, biologically irrelevant salt concentrations, both PLL-g-PEG and PLL-g-PMOXA desorb from the surface because of strong screening of the electrostatic interaction. Recently, PLL-g-PEG was covalently linked to an aldehyde plasma polymer to overcome this limitation. In this case, the layer was stable and resistant to protein adsorption up to very high ionic strengths (2.4 mol/L NaCl).31
    • 31


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.