Lac-time?

Critical Care Medicine

Volumn 32, Issue 8, 2004, Pages 1785-1786

  Trzeciak, Stephen ^a  

^a Department of Anesthesiology   (United States)

Author keywords

Early goal directed therapy; Emergency medicine; Emergency service hospital; Lactate; Sepsis; Septic shock; Severe sepsis

Indexed keywords

LACTIC ACID;

ANAEROBIC METABOLISM; EDITORIAL; EMERGENCY TREATMENT; HUMAN; LACTATE BLOOD LEVEL; METABOLIC CLEARANCE RATE; MORTALITY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PRIORITY JOURNAL; RESUSCITATION; SEPSIS; SEPTIC SHOCK;

BIOLOGICAL MARKERS; EMERGENCY MEDICAL SERVICES; HUMANS; LACTIC ACID; OUTCOME AND PROCESS ASSESSMENT (HEALTH CARE); SEPSIS; SHOCK, SEPTIC; SURVIVAL ANALYSIS;

EID: 3943082766     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000134837.18530.14     Document Type: Editorial

References (12)

1. Karimova A, Pinsky DJ: The endothelial response to oxygen deprivation: Biology and clinical implications. Intensive Care Med 2001; 27:19-31
2. Aird WC: The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood 2003; 101:3765-3777
3. Rivers E, Nguyen B, Havstad S, et al: Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001; 345:1368-1377
4. James JH, Luchette FA, McCarter FD, et al: Lactate is an unreliable indicator of tissue hypoxia in injury or sepsis. Lancet 1999; 354:505-508
5. Bakker J: Lactate: may I have your votes please? Intensive Care Med 2001; 27:6-11
6. Aduen J, Bernstein WK, Khastgir T, et al: The use and clinical importance of a substrate-specific electrode for rapid determination of blood lactate concentrations. JAMA 1994; 272:1678-1685
7. Bakker J, Coffernils M, Leon M, et al: Blood lactate concentrations are superior to oxygen-derived variables in predicting outcome in human septic shock. Chest 1991; 99: 956-962
8. Nguyen HB, Rivers EP, Knoblich BP, et al: Early lactate clearance is associated with improved outcome in severe sepsis and septic shock. Crit Care Med 2004; 32:1637-1642
9. Bakker J, Gris P, Coffernils M, et al: Serial blood lactate concentrations can predict the development of multiple organ failure following septic shock. Am J Surg 1996; 171: 221-226
10. Vincent JL, Abraham E, Annane D, et al: Reducing mortality in sepsis: new directions. Crit Care 2002; 6 (Suppl 3):S1-S18
11. De Backer D, Creteur J, Preiser JC, et al: Microvascular blood flow is altered in patients with sepsis. Am J Respir Crit Care Med 2002; 166:98-104
12. Dellinger RP, Carlet JM, Masur H, et al: Surviving sepsis campaign guidelines for management of severe sepsis and septic shock. Crit Care Med 2004; 32:858-873