In situ monitoring of soil dissolution dynamics: A rapid and simple method for determining worst-case soils for cleaning validation

PDA Journal of Pharmaceutical Science and Technology

Volumn 58, Issue 4, 2004, Pages 203-214

  Sharnez, Rizwan ^a   Lathia, Justin ^b   Kahlenberg, David ^a   Prabhu, Sunil ^a   Dekleva, Michael ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b DREXEL UNIVERSITY   (United States)

Author keywords

Cleaning; Conductivity; Multi product equipment; Parenteral; Validation; Worst case soil

Indexed keywords

PARENTERAL SOLUTION;

ACCURACY; ARTICLE; CLEANING; DISSOLUTION; DYNAMICS; ELECTRIC CONDUCTIVITY; EQUIPMENT; EXPERIMENT; MONITORING; MULTIPRODUCT EQUIPMENT; QUALITY CONTROL; REPRODUCIBILITY; SOIL; TECHNIQUE; VALIDATION PROCESS; WORST CASE SOIL;

DRUG CONTAMINATION; DRUG INDUSTRY; ELECTRIC CONDUCTIVITY; EQUIPMENT CONTAMINATION; HYGIENE; INJECTIONS; MODELS, THEORETICAL; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOIL POLLUTANTS; SOLUBILITY; SOLUTIONS; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS;

EID: 3943079286     PISSN: 10797440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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