A physician with a positive hepatitis C virus RNA test after a needlestick injury

European Journal of Gastroenterology and Hepatology

Volumn 15, Issue 12, 2003, Pages 1367-1369

  Weegink, Christine J ^a   Sentjens, Roel E ^a   Van Der Heyden, Jeroen F ^a   Chamuleau, Robert A ^a   Tytgat, Guido M ^a   Beld, Marcel G ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Acute hepatitis C; Early treatment; Healthcare workers; Needlestick injury

Indexed keywords

ALANINE AMINOTRANSFERASE; RECOMBINANT ALPHA INTERFERON; RIBAVIRIN; VIRUS RNA;

ADULT; ARTICLE; CASE REPORT; CLINICAL FEATURE; DISEASE COURSE; DNA DETERMINATION; HEMOPHILIA; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; MALE; NEEDLESTICK INJURY; NONHUMAN; PHYSICIAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SEROCONVERSION; TREATMENT OUTCOME;

ACUTE DISEASE; ADULT; ANTIVIRAL AGENTS; DISEASE TRANSMISSION, PATIENT-TO-PROFESSIONAL; HEPACIVIRUS; HEPATITIS C; HUMANS; LONG-TERM CARE; MALE; MEDICAL STAFF, HOSPITAL; NEEDLESTICK INJURIES; RNA, VIRAL;

EID: 3943071700     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-200312000-00017     Document Type: Article

References (10)

1. Sulkowski MS, Ray SC, Thomas DL. Needlestick transmission of hepatitis C. JAMA 2002; 287:2406-2413.
2. Cariani E, Zonaro A, Primi D, Magni E, Incarbone C, Scalia P, et al. Detection of HCV RNA and antibodies to HCV after needlestick injury. Lancet 1991; 337:850.
3. Mitsui T, Iwano K, Masuko K, Yamazaki C, Okamoto H, Tsuda F, et al. Hepatitis C virus infection in medical personnel after needlestick accident. Hepatology 1992; 16:1109-1114.
4. Sodeyama T, Kiyosawa K, Urushihara A, Matsumoto A, Tanaka E, Furuta S, et al. Detection of hepatitis C virus markers and hepatitis C virus genomic-RNA after needlestick accidents. Arch Intern Med 1993; 153:1565-1572.
5. Nakano Y, Kiyosawa K, Sodeyama T, Tanaka E, Matsumoto A, Ichijo T, et al. Acute hepatitis C transmitted by needlestick accident despite short duration interferon treatment. J Gastroenterol Hepatol 1995; 10:609-611.
6. Jaeckel E, Cornberg M, Wedemeyer H, Santantonio T, Mayer J, Zankel M, et al. Treatment of acute hepatitis C with interferon alfa-2b. N Engl J Med 2001; 345:1452-1457.
7. Manns MP, McHutchison JG, Gordon SC, Rustgi VK, Shiffman M, Reindollar R, et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 2001; 358:958-965.
8. Beld M, Penning M, McMorrow M, Gorgels J, van den HA, Goudsmit J. Different hepatitis C virus (HCV) RNA load profiles following seroconversion among injecting drug users without correlation with HCV genotype and serum alanine aminotransferase levels. J Clin Microbiol 1998; 36:872-877.
9. Villano SA, Vlahov D, Nelson KE, Cohn S, Thomas DL. Persistence of viremia and the importance of long-term follow-up after acute hepatitis C infection. Hepatology 1999; 29:908-914.
10. Farci P, Alter HJ, Wong D, Miller RH, Shih JW, Jett B, et al. A long-term study of hepatitis C virus replication in non-A, non-B hepatitis. N Engl J Med 1991; 325:98-104.