Relationship between fibrinogen Bβ gene FGB - 455G/A polymorphism and atherosclerotic cerebral infarction

Chinese Journal of Medical Genetics

Volumn 21, Issue 4, 2004, Pages 382-385

  Sun, Hui ^a   Lu, Fang Hong ^a   Tian, Qi ^a   Wen, Pei E ^b   Wu, Fan ^a   Wang, Xin ^c  

^a Dept of Cardiocerebrolvascular Dis ^*

^b SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^c SHANDONG UNIVERSITY   (China)

Author keywords

Cerebral infarction; Fibrinogen; Genetic polymorphism

Indexed keywords

DNA; FIBRINOGEN;

ADULT; AGED; ALLELE; ARTICLE; BRAIN ATHEROSCLEROSIS; BRAIN INFARCTION; CEREBROVASCULAR DISEASE; CHINESE; CIGARETTE SMOKING; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA SEQUENCE; FEMALE; FIBRINOGEN BLOOD LEVEL; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

EID: 3943063720     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Wilhelmsen L, Svardsudd K, Korsan-Bengtsen K, et al. Fibrinogen as a risk factor for stroke and myocardial infarction. N Engl J Med, 1984, 311: 501-505.
2. Carter AM, Catto AJ, Bamford JM, et al. Gender-specific associations of the fibrinogen Bβ448 polymorphism, fibrinogen levels and acute cerebrovascular disease. Arterioscler Thromb Vasc Biol, 1997, 17: 589-594.
3. Thomas AE, Green FR, Kelleher CH, et al. Variation in the promoter region of the β-fibrinogen gene is associated with plasma fibrinogen levels on smokers and non-smokers. Thromb Haemost, 1991, 65: 487-490.
4. Smith EB, Thompson WD. Fibrin as a factor in atherogenesis. Thomb Res, 1994, 73: 1-19.
5. Lowe GD. Fibrinogen and cardiovascular disease: historical introduction. Eur Heart J, 1995, 16(Suppl A): 2-5.
6. Nishiuma S, Kario K, Yakushijin K, et al. Genetic variation in the promoter region of the beta-fibrinogen gene is associated with ischemic stroke in a Japanese population. Blood Coagul Fibrinolysis, 1998, 9: 373-379.
7. Kessler C, Spitzer C, Stauske D, et al. The apolipoprotein E and β-fibrinogen G/A-455 gene polymorphisms are associated with ischemic stroke involving large-vessel disease. Arterioscler Thromb Vasc Biol, 1997, 17: 2880-2884.
8. Fowkes FG, Connor JM, Smith FB, et al. Fibrinogen genotype and risk of peripheral atherosclerosis. Lancet, 1992, 339: 693-696.
9. Humphries SE, Luong LA, Montgomery HE, et al. Gene-environment interaction in the determination of levels of plasma fibrinogen. Thromb Haemost, 1999, 82: 818-825.
10. Lowe GD, Fowkes FG, Dawes J, et al. Blood viscosity, fibrinogen, and activation of coagulation and leukocytes in peripheral arterial disease and the normal population in the Edinburgh artery study. Circulation, 1993, 87: 1915-1920.