One-pot synthesis of 3-fluoro-4-(trifluoromethyl)quinolines from pentafluoropropen-2-ol and their molecular modification

Journal of Organic Chemistry

Volumn 73, Issue 4, 2008, Pages 1468-1474

  Hosokawa, Tsuyoshi ^a   Matsumura, Akemi ^a   Katagiri, Toshimasa ^a   Uneyama, Kenji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOPHILIC SUBSTITUTION; QUINOLINES;

ACETONE; ALCOHOLS; CHEMICAL MODIFICATION; NUCLEOPHILES; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

AROMATIC COMPOUNDS;

1 FLUORO 8 METHOXY 4 PHENYL 3H PYRAZOLO[3,4 C]QUINOLINE; 2 (3 CHLOROPHENYL) 3 FLUORO 6 METHOXY 4 (TRIFLUOROMETHYL)QUINOLINE; 3 ETHOXY 6 METHOXY 2 PHENYL 4 (TRIFLUOROMETHYL)QUINOLINE; 3 FLUORO 2 (4 FLUOROPHENYL) 6 METHOXY 4 (TRIFLUOROMETHYL)QUINOLINE; 3 FLUORO 2 PHENYL 4 (TRIFLUOROMETHYL)BENZO[H]QUINOLINE; 3 FLUORO 6 METHOXY 2 (4 METHYLPHENYL) 4 (TRIFLUOROMETHYL)QUINOLINE; 3 FLUORO 6 METHOXY 2 PHENYL 4 (TRIFLUOROMETHYL)QUINOLINE; 3,3 DIFLUORO 6 METHOXY 2 PHENYL 4 (TRIFLUOROMETHYL) 1,2,3,4 TETRAHYDROQUINOLIN 4 OL; 6 METHOXY 2 PHENYL 3 (PHENYLSULFENYL) 4 (TRIFLUOROMETHYL)QUINOLINE; 6 METHOXY 2 PHENYL 3 [(1 PHENYLETHENYL)OXY] 4 (TRIFLUOROMETHYL)QUINOLINE; 6 METHOXY 2 PHENYL 4 (TRIFLUOROMETHYL)QUINOLIN 3 AMINE; 6 METHOXY 2 PHENYL 4 (TRIFLUOROMETHYL)QUINOLIN 3 OL; 6 METHOXY 2 PHENYL 4 (TRIFLUOROMETHYL)QUINOLINE; 6 METHOXY 2 PHENYL 4 (TRIFLUOROMETHYL)QUINOLINE 3 CARBONITRILE; ETHYL 3 FLUORO 6 METHOXY 4 (TRIFLUOROMETHYL)QUINOLINE 2 CARBOXYLIC ACID; FLUORINE; FUNCTIONAL GROUP; HEXAFLUOROACETONE; HYDRAZINE; MAGNESIUM DERIVATIVE; METHYL GROUP; PENTAFLUOROPROPEN 2 OL; PHENOL DERIVATIVE; PYRAZOLE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

AROMATIZATION; ARTICLE; BIOTRANSFORMATION; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL MODIFICATION; CYCLIZATION; DRUG ACTIVITY; FLUORINATION; FLUORINE NUCLEAR MAGNETIC RESONANCE; MANNICH REACTION; MOLECULAR INTERACTION; ONE POT SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ALKENES; MAGNETIC RESONANCE SPECTROSCOPY; QUINOLINES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, INFRARED;

EID: 39349096527     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo702568z     Document Type: Article

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