6-Azathymidine-4′-thionucleosides: Synthesis and antiviral evaluation

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 23, Issue 1, 2008, Pages 56-61

  Jasamai, Malina ^a   Balzarini, Jan ^b   Simons, Claire ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

6 Azathymidine 4 thionucleosides; Antiviral; Dideoxynucleoside; L nucleoside; Thymidine kinase deficient (TK )

Indexed keywords

2',3' DIDEOXY 4' THIO BETA DEXTRO ERYTHROPENTOFURANOSYL 1' (6 AZATHYMINE); 2',3',5' TRI O ACETYL 4' THIO BETA LEVO 6 AZATHYMIDINE; 3' O THIOCARBONYLIMIDAZOLE 5' O TERT BUTYLDIMETHYLSILYL 2' DEOXY 4' THIO BETA DEXTRO ERYTHROPENTOFURANOSYL 1' (6 AZATHYMINE); 4' THIO BETA LEVO 6 AZATHYMIDINE; 5 (2 BROMOVINYL) 2' DEOXYURIDINE; 5' O TERT BUTYLDIMETHYLSILYL 2' DEOXY 4' THIO BETA DEXTRO ERYTHROPENTOFURANOSYL 1' (6 AZATHYMINE); 5' O TERT BUTYLDIMETHYLSILYL 2',3' DIDEOXY 4' THIO BETA DEXTRO ERYTHROPENTOFURANOSYL 1' (6 AZATHYMINE); ACICLOVIR; ANTIINFECTIVE AGENT; ANTIVIRUS AGENT; GANCICLOVIR; THYMIDINE DERIVATIVE; THYMIDINE KINASE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME PHOSPHORYLATION; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE; VACCINIA VIRUS; VIRUS INHIBITION; VIRUS STRAIN;

ACYCLOVIR; ANTIVIRAL AGENTS; BROMODEOXYURIDINE; GANCICLOVIR; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; THIONUCLEOSIDES; THYMIDINE;

HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 2; SIMPLEXVIRUS; VACCINIA VIRUS;

EID: 39349094002     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360701442340     Document Type: Article

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