Age-related decrease in 15-lipoxygenase contributes to reduced vasorelaxation in rabbit aorta

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 294, Issue 2, 2008, Pages

  Tang, Xin ^a   Aggarwal, Nitin ^a   Holmes, Blythe B ^a   Kuhn, Hartmut ^b   Campbell, William B ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Acetylcholine; Arachidonic acid; Endothelium derived hyperpolarizing factor; Vasodilation

Indexed keywords

11,12,15 TRIHYDROXYEICOSATRIENOIC ACID; 15 HYDROPEROXYARACHIDONIC ACID; 15 HYDROXY 11,12 EPOXYEICOSATRIENOIC ACID; ACETYLCHOLINE; ARACHIDONATE 15 LIPOXYGENASE; ARACHIDONIC ACID; ARGININE; EPOXYICOSATRIENOIC ACID; INDOMETACIN; NITROPRUSSIDE SODIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; AORTA; ARACHIDONIC ACID METABOLISM; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; RABBIT; VASODILATATION;

8,11,14-EICOSATRIENOIC ACID; ACETYLCHOLINE; AGING; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; AORTA; ARACHIDONATE 15-LIPOXYGENASE; ARACHIDONIC ACID; BIOLOGICAL FACTORS; BLOTTING, WESTERN; CLONING, MOLECULAR; KINETICS; MOLECULAR SEQUENCE DATA; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; NITROPRUSSIDE; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; VASODILATOR AGENTS;

EID: 39149144510     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01053.2007     Document Type: Article

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