메뉴 건너뛰기




Volumn 44, Issue 2, 2008, Pages 172-180

Melatonin preserves superoxide dismutase activity in hypoglossal motoneurons of adult rats following peripheral nerve injury

Author keywords

Functional recovery; Hypoglossal nucleus; Melatonin; Nitric oxide; Peripheral nerve injury; Quantitative image analysis; Superoxide dismutase

Indexed keywords

CHOLINE ACETYLTRANSFERASE; COPPER ZINC SUPEROXIDE DISMUTASE; MANGANESE SUPEROXIDE DISMUTASE; MELATONIN; NITRIC OXIDE SYNTHASE; SUPEROXIDE DISMUTASE;

EID: 39149142496     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2007.00505.x     Document Type: Article
Times cited : (38)

References (53)
  • 1
    • 0035424661 scopus 로고    scopus 로고
    • Peripheral nerve injury: A review and approach to tissue engineered constructs
    • Evans GR. Peripheral nerve injury: a review and approach to tissue engineered constructs. Anat Rec 2001 263 : 396 404.
    • (2001) Anat Rec , vol.263 , pp. 396-404
    • Evans, G.R.1
  • 3
    • 34249728741 scopus 로고    scopus 로고
    • Promoting anatomical plasticity and recovery of function after traumatic injury to the central or peripheral nervous system
    • Priestley JV. Promoting anatomical plasticity and recovery of function after traumatic injury to the central or peripheral nervous system. Brain 2007 130 : 895 897.
    • (2007) Brain , vol.130 , pp. 895-897
    • Priestley, J.V.1
  • 4
    • 0024361012 scopus 로고
    • Morphological and physiological properties of neurons after long-term axonal regeneration: Observations on chronic and delayed sequelae of peripheral nerve injury
    • Bowe CM, Hildebrand C, Kocsis JD et al. Morphological and physiological properties of neurons after long-term axonal regeneration: observations on chronic and delayed sequelae of peripheral nerve injury. J Neurol Sci 1989 91 : 259 292.
    • (1989) J Neurol Sci , vol.91 , pp. 259-292
    • Bowe, C.M.1    Hildebrand, C.2    Kocsis, J.D.3
  • 6
    • 0036723908 scopus 로고    scopus 로고
    • Analysis of genes induced in peripheral nerve after axotomy using cDNA microarrays
    • Kubo T, Yamashita T, Yamaguchi A et al. Analysis of genes induced in peripheral nerve after axotomy using cDNA microarrays. J Neurochem 2002 82 : 1129 1136.
    • (2002) J Neurochem , vol.82 , pp. 1129-1136
    • Kubo, T.1    Yamashita, T.2    Yamaguchi, A.3
  • 7
    • 27244441421 scopus 로고    scopus 로고
    • The response to injury in the peripheral nervous system
    • Hall S. The response to injury in the peripheral nervous system. J Bone Joint Surg Br 2005 87 : 1309 1319.
    • (2005) J Bone Joint Surg Br , vol.87 , pp. 1309-1319
    • Hall, S.1
  • 8
    • 0028208771 scopus 로고
    • Nerve injury increases the susceptibility of motoneurons to N-methyl-D-aspartate-induced neurotoxicity in the developing rat
    • Greensmith L, Hasan HI, Vrbova G. Nerve injury increases the susceptibility of motoneurons to N-methyl-D-aspartate-induced neurotoxicity in the developing rat. Neuroscience 1994 58 : 727 733.
    • (1994) Neuroscience , vol.58 , pp. 727-733
    • Greensmith, L.1    Hasan, H.I.2    Vrbova, G.3
  • 9
    • 0030944883 scopus 로고    scopus 로고
    • Mechanism of calcium entry during axon injury and degeneration
    • Lopachin RM, Lehning EJ. Mechanism of calcium entry during axon injury and degeneration. Toxicol Appl Pharmacol 1997 143 : 233 244.
    • (1997) Toxicol Appl Pharmacol , vol.143 , pp. 233-244
    • Lopachin, R.M.1    Lehning, E.J.2
  • 10
    • 30744467942 scopus 로고    scopus 로고
    • Nitric oxide in damage, disease and repair of the peripheral nervous system
    • Zochodne DW, Levy D. Nitric oxide in damage, disease and repair of the peripheral nervous system. Cell Mol Biol 2005 51 : 255 267.
    • (2005) Cell Mol Biol , vol.51 , pp. 255-267
    • Zochodne, D.W.1    Levy, D.2
  • 11
    • 0034656849 scopus 로고    scopus 로고
    • Reactive oxygen species, cell signaling, and cell injury
    • Hensley K, Robinson KA, Gabbita SP et al. Reactive oxygen species, cell signaling, and cell injury. Free Radic Biol Med 2000 28 : 1456 1462.
    • (2000) Free Radic Biol Med , vol.28 , pp. 1456-1462
    • Hensley, K.1    Robinson, K.A.2    Gabbita, S.P.3
  • 13
    • 0032864716 scopus 로고    scopus 로고
    • Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis
    • Martin LJ, Kaiser A, Price AC. Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis. J Neurobiol 1999 40 : 185 201.
    • (1999) J Neurobiol , vol.40 , pp. 185-201
    • Martin, L.J.1    Kaiser, A.2    Price, A.C.3
  • 14
    • 0037380788 scopus 로고    scopus 로고
    • Early events of target deprivation/axotomy-induced neuronal apoptosis in vivo: Oxidative stress, DNA damage, p53 phosphorylation and subcellular redistribution of death proteins
    • Martin LJ, Price AC, Mcclendon KB et al. Early events of target deprivation/axotomy-induced neuronal apoptosis in vivo: oxidative stress, DNA damage, p53 phosphorylation and subcellular redistribution of death proteins. J Neurochem 2003 85 : 234 247.
    • (2003) J Neurochem , vol.85 , pp. 234-247
    • Martin, L.J.1    Price, A.C.2    McClendon, K.B.3
  • 16
  • 17
    • 20044366019 scopus 로고    scopus 로고
    • Oxidative stress, antioxidants and neurodegenerative diseases
    • Casetta I, Govoni V, Granieri E. Oxidative stress, antioxidants and neurodegenerative diseases. Curr Pharm Des 2005 11 : 2033 2052.
    • (2005) Curr Pharm des , vol.11 , pp. 2033-2052
    • Casetta, I.1    Govoni, V.2    Granieri, E.3
  • 18
    • 33947612587 scopus 로고    scopus 로고
    • Redox control of neural function: Background, mechanisms, and significance
    • Maher P. Redox control of neural function: background, mechanisms, and significance. Antioxid Redox Signal 2006 8 : 1941 1970.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1941-1970
    • Maher, P.1
  • 19
    • 0030465501 scopus 로고    scopus 로고
    • Superoxide dismutase and oxygen radical neurotoxicity
    • Hosler BA, Brown RH JR. Superoxide dismutase and oxygen radical neurotoxicity. Curr Opin Neurol 1996 9 : 486 491.
    • (1996) Curr Opin Neurol , vol.9 , pp. 486-491
    • Hosler, B.A.1    Brown Jr., R.H.2
  • 20
    • 0036323863 scopus 로고    scopus 로고
    • Role of superoxide dismutases in oxidative damage and neurodegenerative disorders
    • Maier CM, Chan PH. Role of superoxide dismutases in oxidative damage and neurodegenerative disorders. Neuroscientist 2002 8 : 323 334.
    • (2002) Neuroscientist , vol.8 , pp. 323-334
    • Maier, C.M.1    Chan, P.H.2
  • 21
    • 0002399828 scopus 로고
    • Phylogenic distribution of three types of superoxide dismutase in organisms and in cell organelles
    • In: Bannister, J.V., Hill, H.A.O., eds. Elsevier, Amsterdam, pp.
    • Asada K, Kanematsu S, Okada S et al. Phylogenic distribution of three types of superoxide dismutase in organisms and in cell organelles. In : Chemical and Biochemical Aspects of Superoxide and Superoxide Dismutase. Bannister JV, Hill HAO, eds. Elsevier, Amsterdam, 1980 pp. 136 153.
    • (1980) Chemical and Biochemical Aspects of Superoxide and Superoxide Dismutase. , pp. 136-153
    • Asada, K.1    Kanematsu, S.2    Okada, S.3
  • 22
    • 0028815433 scopus 로고
    • Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons
    • Pardo CA, Xu Z, Borchelt DR et al. Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Proc Natl Acad Sci USA 1995 92 : 954 958.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 954-958
    • Pardo, C.A.1    Xu, Z.2    Borchelt, D.R.3
  • 23
    • 0033987488 scopus 로고    scopus 로고
    • Cellular distribution of superoxide dismutases in the rat CNS
    • Lindenau J, Noack H, Possel H et al. Cellular distribution of superoxide dismutases in the rat CNS. Glia 2000 29 : 25 34.
    • (2000) Glia , vol.29 , pp. 25-34
    • Lindenau, J.1    Noack, H.2    Possel, H.3
  • 24
    • 0034930671 scopus 로고    scopus 로고
    • Free radical-mediated molecular damage. Mechanisms for the protective actions of melatonin in the central nervous system
    • Reiter RJ, Acuna-Castroviejo D, Tan DX et al. Free radical-mediated molecular damage. Mechanisms for the protective actions of melatonin in the central nervous system. Ann N Y Acad Sci 2001 939 : 200 215.
    • (2001) Ann N Y Acad Sci , vol.939 , pp. 200-215
    • Reiter, R.J.1    Acuna-Castroviejo, D.2    Tan, D.X.3
  • 25
    • 1042279497 scopus 로고    scopus 로고
    • Melatonin: Detoxification of oxygen and nitrogen-based toxic reactants
    • Reiter RJ, Tan DX, Manchester LC et al. Melatonin: detoxification of oxygen and nitrogen-based toxic reactants. Adv Exp Med Biol 2003 527 : 539 548.
    • (2003) Adv Exp Med Biol , vol.527 , pp. 539-548
    • Reiter, R.J.1    Tan, D.X.2    Manchester, L.C.3
  • 26
    • 33749319658 scopus 로고    scopus 로고
    • Interactions of melatonin and its metabolites with the ABTS cation radical: Extension of the radical scavenger cascade and formation of a novel class of oxidation products, C2-substituted 3-indolinones
    • Rosen J, Than NN, Koch D et al. Interactions of melatonin and its metabolites with the ABTS cation radical: extension of the radical scavenger cascade and formation of a novel class of oxidation products, C2-substituted 3-indolinones. J Pineal Res 2006 41 : 374 381.
    • (2006) J Pineal Res , vol.41 , pp. 374-381
    • Rosen, J.1    Than, N.N.2    Koch, D.3
  • 27
    • 34147201601 scopus 로고    scopus 로고
    • AFMK, a melatonin metabolite, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice
    • Manda K, Ueno M, Anzai K. AFMK, a melatonin metabolite, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice. J Pineal Res 2007 42 : 386 393.
    • (2007) J Pineal Res , vol.42 , pp. 386-393
    • Manda, K.1    Ueno, M.2    Anzai, K.3
  • 28
    • 33845536018 scopus 로고    scopus 로고
    • One molecule, many derivatives: A never-ending interaction of melatonin with reactive oxygen and nitrogen species?
    • Tan DX, Manchester LC, Terron MP et al. One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species? J Pineal Res 2007 42 : 28 42.
    • (2007) J Pineal Res , vol.42 , pp. 28-42
    • Tan, D.X.1    Manchester, L.C.2    Terron, M.P.3
  • 29
    • 23744513206 scopus 로고    scopus 로고
    • A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes
    • Tomas-Zapico C, Coto-Montes A. A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes. J Pineal Res 2005 39 : 99 104.
    • (2005) J Pineal Res , vol.39 , pp. 99-104
    • Tomas-Zapico, C.1    Coto-Montes, A.2
  • 30
    • 0033998384 scopus 로고    scopus 로고
    • Melatonin increases activities of glutathione peroxidase and superoxide dismutase in fetal rat brain
    • Okatani Y, Wakatsuki A, Kaneda C. Melatonin increases activities of glutathione peroxidase and superoxide dismutase in fetal rat brain. J Pineal Res 2000 28 : 89 96.
    • (2000) J Pineal Res , vol.28 , pp. 89-96
    • Okatani, Y.1    Wakatsuki, A.2    Kaneda, C.3
  • 31
    • 0034806630 scopus 로고    scopus 로고
    • Melatonin inhibits lipid peroxidation and stimulates the antioxidant status of diabetic rats
    • Vural H, Sabuncu T, Arslan SO et al. Melatonin inhibits lipid peroxidation and stimulates the antioxidant status of diabetic rats. J Pineal Res 2001 31 : 193 198.
    • (2001) J Pineal Res , vol.31 , pp. 193-198
    • Vural, H.1    Sabuncu, T.2    Arslan, S.O.3
  • 32
    • 18544403693 scopus 로고    scopus 로고
    • Melatonin stimulates the activity of protective antioxidative enzymes in myocardial cells of rats in the course of doxorubicin intoxication
    • Dziegiel P, Murawska-Cialowicz E, Jethon Z et al. Melatonin stimulates the activity of protective antioxidative enzymes in myocardial cells of rats in the course of doxorubicin intoxication. J Pineal Res 2003 35 : 183 187.
    • (2003) J Pineal Res , vol.35 , pp. 183-187
    • Dziegiel, P.1    Murawska-Cialowicz, E.2    Jethon, Z.3
  • 33
    • 1642562820 scopus 로고    scopus 로고
    • Regulation of antioxidant enzymes: A significant role for melatonin
    • Rodriguez C, Mayo JC, Sainz RM et al. Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res 2004 36 : 1 9.
    • (2004) J Pineal Res , vol.36 , pp. 1-9
    • Rodriguez, C.1    Mayo, J.C.2    Sainz, R.M.3
  • 34
    • 13244253663 scopus 로고    scopus 로고
    • Use of muscle fibrillation for tracking nerve regeneration
    • Heaton JT, Kobler JB. Use of muscle fibrillation for tracking nerve regeneration. Muscle Nerve 2005 31 : 235 241.
    • (2005) Muscle Nerve , vol.31 , pp. 235-241
    • Heaton, J.T.1    Kobler, J.B.2
  • 35
    • 0034846595 scopus 로고    scopus 로고
    • Axotomy along with hypoxia enhances the neuronal NADPH-d/NOS expression in lower brain stem motor neurons of adult rats
    • Chang HM, Lue JH, Wen CY et al. Axotomy along with hypoxia enhances the neuronal NADPH-d/NOS expression in lower brain stem motor neurons of adult rats. Exp Neurol 2001 171 : 116 126.
    • (2001) Exp Neurol , vol.171 , pp. 116-126
    • Chang, H.M.1    Lue, J.H.2    Wen, C.Y.3
  • 36
    • 8644241770 scopus 로고    scopus 로고
    • Differential expression of calcitonin gene-related peptide (CGRP) and choline acetyltransferase (ChAT) in the axotomized motoneurons of normoxic and hypoxic rats
    • Chang HM, Wei IH, Tseng CY et al. Differential expression of calcitonin gene-related peptide (CGRP) and choline acetyltransferase (ChAT) in the axotomized motoneurons of normoxic and hypoxic rats. J Chem Neuroanat 2004 28 : 239 251.
    • (2004) J Chem Neuroanat , vol.28 , pp. 239-251
    • Chang, H.M.1    Wei, I.H.2    Tseng, C.Y.3
  • 37
    • 33746602616 scopus 로고    scopus 로고
    • Total sleep deprivation inhibits the neuronal nitric oxide synthase and cytochrome oxidase reactivities in the nodose ganglion of adult rats
    • Chang HM, Wu UI, Lin TB et al. Total sleep deprivation inhibits the neuronal nitric oxide synthase and cytochrome oxidase reactivities in the nodose ganglion of adult rats. J Anat 2006 209 : 239 250.
    • (2006) J Anat , vol.209 , pp. 239-250
    • Chang, H.M.1    Wu, U.I.2    Lin, T.B.3
  • 38
    • 0025941639 scopus 로고
    • Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with the NADPH-diaphorase
    • Bredt DS, Glatt CE, Hwang PM et al. Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with the NADPH-diaphorase. Neuron 1991 7 : 615 624.
    • (1991) Neuron , vol.7 , pp. 615-624
    • Bredt, D.S.1    Glatt, C.E.2    Hwang, P.M.3
  • 39
    • 85012748571 scopus 로고
    • Image analytic techniques for quantification of immuno-histochemical staining in the nervous system
    • In: Conn, P.M., ed. Academic Press, San Diego, pp.
    • Smolen AJ. Image analytic techniques for quantification of immuno-histochemical staining in the nervous system. In : Methods in Neuroscience: Quantitative and Qualitative Microscopy, Vol. 3. Conn PM, ed. Academic Press, San Diego, 1990 pp. 208 229.
    • (1990) Methods in Neuroscience: Quantitative and Qualitative Microscopy , vol.3 , pp. 208-229
    • Smolen, A.J.1
  • 40
    • 0027160873 scopus 로고
    • Nitric oxide synthase-like immunoreactivity in lumbar dorsal root ganglia and spinal cord of rat and monkey and effect of peripheral axotomy
    • Zhang X, Verge V, Wiesenfeld-Hallin Z et al. Nitric oxide synthase-like immunoreactivity in lumbar dorsal root ganglia and spinal cord of rat and monkey and effect of peripheral axotomy. J Comp Neurol 1993 335 : 563 575.
    • (1993) J Comp Neurol , vol.335 , pp. 563-575
    • Zhang, X.1    Verge, V.2    Wiesenfeld-Hallin, Z.3
  • 41
    • 0028825290 scopus 로고
    • The role of nitric oxide in facial motoneuronal death
    • Ruan RS, Leong SK, Yeoh KH. The role of nitric oxide in facial motoneuronal death. Brain Res 1995 698 : 163 168.
    • (1995) Brain Res , vol.698 , pp. 163-168
    • Ruan, R.S.1    Leong, S.K.2    Yeoh, K.H.3
  • 42
    • 0030989953 scopus 로고    scopus 로고
    • Regulation of nitric oxide synthase expression in motoneurons following nerve injury
    • Yu WHA. Regulation of nitric oxide synthase expression in motoneurons following nerve injury. Dev Neurosci 1997 19 : 247 254.
    • (1997) Dev Neurosci , vol.19 , pp. 247-254
    • Yu, W.H.A.1
  • 43
    • 0036275552 scopus 로고    scopus 로고
    • Spatial and temporal correlation of nitric oxide synthase expression with CnZn-superoxide dismutase reduction in motor neurons following axotomy
    • Yu WHA. Spatial and temporal correlation of nitric oxide synthase expression with CnZn-superoxide dismutase reduction in motor neurons following axotomy. Ann N Y Acad Sci 2002 962 : 111 121.
    • (2002) Ann N Y Acad Sci , vol.962 , pp. 111-121
    • Yu, W.H.A.1
  • 44
    • 0032844326 scopus 로고    scopus 로고
    • Effect of acrylamide on neurological recovery following spinal cord injury in rats
    • Al Moutaery K, Morais C, Biary N et al. Effect of acrylamide on neurological recovery following spinal cord injury in rats. Acta Neurochir (Wien) 1999 141 : 989 998.
    • (1999) Acta Neurochir (Wien) , vol.141 , pp. 989-998
    • Al Moutaery, K.1    Morais, C.2    Biary, N.3
  • 45
    • 0035882524 scopus 로고    scopus 로고
    • A role for free radicals and nitric oxide in delayed recovery in aged rats with chronic constriction nerve injury
    • Khalil Z, Khodr B. A role for free radicals and nitric oxide in delayed recovery in aged rats with chronic constriction nerve injury. Free Radic Biol Med 2001 31 : 430 439.
    • (2001) Free Radic Biol Med , vol.31 , pp. 430-439
    • Khalil, Z.1    Khodr, B.2
  • 46
    • 0343962623 scopus 로고    scopus 로고
    • Melatonin attenuates neuronal NADPH-d/NOS expression in the hypoglossal nucleus of adult rats following peripheral nerve injury
    • Chang HM, Ling EA, Lue JH et al. Melatonin attenuates neuronal NADPH-d/NOS expression in the hypoglossal nucleus of adult rats following peripheral nerve injury. Brain Res 2000 873 : 243 251.
    • (2000) Brain Res , vol.873 , pp. 243-251
    • Chang, H.M.1    Ling, E.A.2    Lue, J.H.3
  • 47
    • 12244304145 scopus 로고    scopus 로고
    • The chemistry of melatonin's interaction with reactive species
    • Allegra M, Reiter RJ, Tan DX et al. The chemistry of melatonin's interaction with reactive species. J Pineal Res 2003 34 : 1 10.
    • (2003) J Pineal Res , vol.34 , pp. 1-10
    • Allegra, M.1    Reiter, R.J.2    Tan, D.X.3
  • 48
    • 0020423551 scopus 로고
    • Synthesizing enzymes for four neuroactive substances in motor neurons and neuromuscular junctions: Light and electron microscopic immunocytochemistry
    • Chan-Palay V, Engel AG, Palay SL et al. Synthesizing enzymes for four neuroactive substances in motor neurons and neuromuscular junctions: light and electron microscopic immunocytochemistry. Proc Natl Acad Sci USA 1982 79 : 6717 6721.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 6717-6721
    • Chan-Palay, V.1    Engel, A.G.2    Palay, S.L.3
  • 49
    • 0029133815 scopus 로고
    • Differential regulation of motor neuron survival and choline acetyltransferase expression following axotomy
    • Kou SY, Chiu AY, Patterson PH. Differential regulation of motor neuron survival and choline acetyltransferase expression following axotomy. J Neurobiol 1995 27 : 561 572.
    • (1995) J Neurobiol , vol.27 , pp. 561-572
    • Kou, S.Y.1    Chiu, A.Y.2    Patterson, P.H.3
  • 50
    • 0018963557 scopus 로고
    • Axon reaction in dorsal motor vagal and hypoglossal neurons of the adult rat. Light microscopy and RNA-cytochemistry
    • Aldskogius H, Barron KD, Regal R. Axon reaction in dorsal motor vagal and hypoglossal neurons of the adult rat. Light microscopy and RNA-cytochemistry. J Comp Neurol 1980 193 : 165 177.
    • (1980) J Comp Neurol , vol.193 , pp. 165-177
    • Aldskogius, H.1    Barron, K.D.2    Regal, R.3
  • 51
    • 0019349967 scopus 로고
    • Effects of testosterone and 5-alpha-dihydrotestosterone on regeneration of the hypoglossal nerve in rats
    • Yu WHA, Srinivasan R. Effects of testosterone and 5-alpha- dihydrotestosterone on regeneration of the hypoglossal nerve in rats. Exp Neurol 1981 71 : 431 435.
    • (1981) Exp Neurol , vol.71 , pp. 431-435
    • Yu, W.H.A.1    Srinivasan, R.2
  • 52
    • 13544264637 scopus 로고    scopus 로고
    • Superoxide dismutase isoforms 1 and 2 in lumbar spinal cord of neonatal rats after sciatic nerve transection and melatonin treatment
    • Rogerio F, Teixeira SA, De Rezende AC et al. Superoxide dismutase isoforms 1 and 2 in lumbar spinal cord of neonatal rats after sciatic nerve transection and melatonin treatment. Brain Res Dev Brain Res 2005 154 : 217 225.
    • (2005) Brain Res Dev Brain Res , vol.154 , pp. 217-225
    • Rogerio, F.1    Teixeira, S.A.2    De Rezende, A.C.3
  • 53
    • 0036809371 scopus 로고    scopus 로고
    • Melatonin regulation of antioxidant enzyme gene expression
    • Mayo JC, Sainz RM, Antolin I et al. Melatonin regulation of antioxidant enzyme gene expression. Cell Mol Life Sci 2002 59 : 1706 1713.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 1706-1713
    • Mayo, J.C.1    Sainz, R.M.2    Antolin, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.