Optimisation of supercritical fluid extraction of indole alkaloids from Catharanthus roseus using experimental design methodology - Comparison with other extraction techniques

Phytochemical Analysis

Volumn 19, Issue 1, 2008, Pages 52-63

  Verma, Arvind ^a   Hartonen, Kari ^a   Riekkola, Marja Liisa ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Catharanthus roseus; Experimental design; Indole alkaloids; Liquid chromatography; Mass spectrometry; Supercritical fluid extraction

Indexed keywords

ALKALOIDS; DESIGN OF EXPERIMENTS; DICHLOROMETHANE; DRUG PRODUCTS; EFFLUENT TREATMENT; ELECTROSPRAY IONIZATION; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; METABOLITES; METHANOL; POLYCYCLIC AROMATIC HYDROCARBONS; STATISTICS; SUPERCRITICAL FLUID EXTRACTION; SUPERCRITICAL FLUIDS; ULTRASONIC APPLICATIONS;

ANALYTES; CATHARANTHINE; CATHARANTHUS ROSEUS; EXTRACTION METHOD; EXTRACTION TECHNIQUES; INDOLE ALKALOIDS; OPTIMISATIONS; SOLID/LIQUID EXTRACTION; SOXHLET EXTRACTION; VINDOLINE;

MASS SPECTROMETRY;

ANHYDROVINBLASTINE; CATHARANTHINE; CATHARANTHUS ROSEUS EXTRACT; DICHLOROMETHANE; INDOLE ALKALOID; METHANOL; SULFURIC ACID; UNCLASSIFIED DRUG; VINBLASTINE; VINBLASTINE DERIVATIVE; VINCRISTINE; VINDOLINE; VINLEUROSINE;

ARTICLE; COMPUTER PROGRAM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; EXPERIMENTAL DESIGN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; ION TRAP MASS SPECTROMETRY; NONHUMAN; PLANT LEAF; RESPONSE SURFACE METHOD; SOLID PHASE EXTRACTION; SOLVENT EXTRACTION; SOXHLET EXTRACTION; SUPERCRITICAL FLUID EXTRACTION; ULTRASOUND; WATER TEMPERATURE;

CATHARANTHUS ROSEUS;

EID: 39149133994     PISSN: 09580344     EISSN: 10991565     Source Type: Journal    
DOI: 10.1002/pca.1015     Document Type: Article

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