A validated reversed phase HPLC method for the determination of process-related impurities in almotriptan malate API

Journal of Pharmaceutical and Biomedical Analysis

Volumn 46, Issue 4, 2008, Pages 792-798

  Kumar, A Phani ^a   Ganesh, V R L ^a   Rao, D V Subba ^a   Anil, C ^a   Rao, B Venugopala ^a   Hariharakrishnan, V S ^a   Suneetha, A ^b   Sundar, B Syama ^c  

^a SMS Pharma Research Center   (India)

^b HINDU COLLEGE OF PHARMACY   (India)

^c ACHARYA NAGARJUNA UNIVERSITY   (India)

Author keywords

Almotriptan; Almotriptan malate; Process related impurities; RP LC; Validation

Indexed keywords

ACETONITRILE; ALMOTRIPTAN; BUFFER; SODIUM DIHYDROGEN PHOSPHATE;

ARTICLE; DRUG STRUCTURE; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; PH; PRIORITY JOURNAL; SEPARATION TECHNIQUE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CONTAMINATION; TRYPTAMINES;

EID: 39149129048     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2007.11.029     Document Type: Article

References (5)

1. D.F Forner, C.P. Duran, J.P. Soto, A.V. Noverola, J.M. Maruti, US Patent 5565447 (1996).
2. Bosch J., Roca T., Armengol M., and Forner D.F. Tetrahedron 57 (2001) 1041-1048
3. Jansat J.M., Tobed A.M., Garcia E., Cabarrocas X., and Costa J. Int. J. Clin. Pharmacol. Ther. 44 (2006) 185-190
4. Fleishaker J.C., Ryan K.K., Jansat J.M., Carel B.J., Bell D.J.A., Burke M.T., and Azie N.E. Br. J. Clin. Pharmacol. 51 (2001) 437-441
5. ICH Q2(R1), Guidelines on Validation of Analytical Procedures: Text and methodology, November 2005.