Lidocaine 2% Gel Versus Plain Lubricating Gel for Pain Reduction During Flexible Cystoscopy: A Meta-Analysis of Prospective, Randomized, Controlled Trials

Journal of Urology

Volumn 179, Issue 3, 2008, Pages 986-990

  Patel, Amit R ^a   Jones, J Stephen ^a   Babineau, Denise ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

bladder; cystoscopy; lidocaine; pain; urethra

Indexed keywords

LIDOCAINE; LUBRICATING AGENT;

ARTICLE; CLINICAL TRIAL; CYSTOSCOPY; GEL; HUMAN; PAIN; PAIN ASSESSMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZATION; VISUAL ANALOG SCALE;

ADMINISTRATION, TOPICAL; AGED; ANESTHETICS, LOCAL; CYSTOSCOPY; GELS; HUMANS; LIDOCAINE; LUBRICANTS; MALE; MIDDLE AGED; PAIN; PROSPECTIVE STUDIES; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 39149113449     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2007.10.065     Document Type: Article

References (20)

1. Pliskin M.J., Kreder K.J., Desmond P.M., and Dresner M.L. Cocaine and lidocaine as topical urethral anesthetics. J Urol 141 (1989) 1117
2. Hozo S.P., Djulbegovic B., and Hozo I. Estimating the mean and variance from the median, range, and the size of a sample. BMC Med Res Methodol 5 (2005) 13
3. Hedges L.V. Distribution theory for Glass's estimator of effect size and related estimators. J Educ Stat 6 (1981) 107
4. Sutton A.J., Abrams K.R., Jones D.R., Sheldon T.A., and Song F. Methods for Meta-Analysis in Medical Research (2000), John Wiley and Sons, Chichester, United Kingdom
5. Choong S., Whitfield H.N., Meganathan V., Nathan M.S., Razack A., and Gleeson M. Prospective, randomized, double-blind study comparing lignocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy. Br J Urol 81 (1998) 178
6. Holmes M., Stewart J., and Rice M. Flexible cystoscopy: is the volume and content of the urethral gel critical?. J Endourol 15 (2001) 855
7. McFarlane N., Denstedt J., Ganapathy S., and Razvi H. Randomized trial of 10 mL and 20 mL of 2% intraurethral lidocaine gel and placebo in men undergoing flexible cystoscopy. J Endourol 15 (2001) 541
8. Palit V., Ashurst H.N., Biyani C.S., Elmasray Y., Puri R., and Shah T. Is using lignocaine gel prior to flexible cystoscopy justified?. A randomized prospective study. Urol Int 71 (2003) 389
9. Rodriguez-Rubio F., Sanz G., Garrido S., Saìnchez C., and Estudillo F. Patient tolerance during outpatient flexible cystoscopy: a prospective, randomized, double-blind study comparing plain lubrication and lidocaine gel. Scand J Urol Nephrol 38 (2004) 477
10. Chen Y.T., Hsiao P.J., Wong W.Y., Wang C.C., Yang S.S.D., and Hsieh C.H. Randomized double-blind comparison of lidocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy. J Endourol 19 (2005) 163
11. Birch B.R., Ratan P., Morley R., Cumming J., Smart C.J., and Jenkins J.D. Flexible cystoscopy in men: is topical anaesthesia with lignocaine gel worthwhile?. Br J Urol 73 (1994) 155
12. Burke D.M., Shackley D.C., and O'Reilly P.H. The community-based morbidity of flexible cystoscopy. BJU Int 89 (2002) 347
13. Dryhurst D.J., and Fowler C.G.A. new small-calibre diagnostic flexible cystoscope. BJU Int 89 (2002) 194
14. Goel R., and Aron M. Cooled lignocaine gel: does it reduce urethral discomfort during instillation?. Int Urol Nephrol 35 (2003) 375
15. Ho K.J., Thompson T.J., O'Brien A., Young M.R.A., and McCleane G. Lignocaine gel: does it cause urethral pain rather than prevent it?. Eur Urol 43 (2003) 194
16. Jayathillake A., Mason D.F., Broome K., and Tan G. Chlorhexidine in urethral gel: does it cause pain at flexible cystoscopy. Urology 67 (2006) 670
17. Khan M.A., Beyzade B., Tau W., Virdi J.S., and Potluri B.S. Effect of the rate of delivery of lignocaine gel on patient discomfort perception prior to performing flexible cystoscopy. Urol Int 68 (2002) 164
18. Hruby G., Ames C., Chen C., Yan Y., Sagar J., and Baron P. Assessment of efficiency of transcutaneous nerve stimulation for pain management during flexible cystoscopy. Urology 67 (2006) 914
19. Kesari D., Kovisman V., Cytron S., and Benjamin J. Effects on pain and anxiety of patients viewing their cystoscopy in addition to a detailed explanation: a controlled study. BJU Int 92 (2003) 751
20. Patel A.R., Jones J.S., Angie S., and Babineau D. Office based flexible cystoscopy may be less painful for men allowed to view the procedure. J Urol 177 (2007) 1843