Therapy of herpes virus infections in children

Advances in Experimental Medicine and Biology

Volumn 609, Issue , 2008, Pages 216-232

  Whitley, Richard J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ANTIALLERGIC AGENT; ATORAX; CALAMINE; DIPHENHYDRAMINE; FAMCICLOVIR; GANCICLOVIR; GRANULOCYTE COLONY STIMULATING FACTOR; PENCICLOVIR; PLACEBO; UNCLASSIFIED DRUG; VALACICLOVIR; VALGANCICLOVIR; VIDARABINE; VIRUS DNA; ANTIVIRUS AGENT;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANEMIA; ANTIVIRAL THERAPY; BONE MARROW SUPPRESSION; CENTRAL NERVOUS SYSTEM INFECTION; CHICKENPOX; CHILD HEALTH CARE; CHILDHOOD MORTALITY; CLINICAL TRIAL; CONFERENCE PAPER; CONTINUOUS INFUSION; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DRUG DOSE REDUCTION; DRUG MEGADOSE; DRUG WITHDRAWAL; EYE INFECTION; GRANULOCYTOPENIA; HEARING IMPAIRMENT; HERPES SIMPLEX; HERPES SIMPLEX ENCEPHALITIS; HERPES VIRUS INFECTION; HERPES ZOSTER; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOCOMPETENCE; MORBIDITY; MOUTH INFECTION; NEUTROPENIA; NEUTROPHIL COUNT; NEWBORN INFECTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PRURITUS; SIDE EFFECT; SKIN INFECTION; THROMBOCYTOPENIA; UNSPECIFIED SIDE EFFECT; VARICELLA ZOSTER VIRUS; VIRUS DETECTION; VIRUS LOAD; ANTIVIRAL RESISTANCE; CHILD; IMMUNE DEFICIENCY; INFANT; MORTALITY; NEWBORN; PRESCHOOL CHILD; REVIEW; VIROLOGY;

CYTOMEGALOVIRUS; HERPES; HERPESVIRIDAE; HUMAN HERPESVIRUS 3; SIMPLEXVIRUS;

ANTIVIRAL AGENTS; CHICKENPOX; CHILD; CHILD, PRESCHOOL; CYTOMEGALOVIRUS INFECTIONS; DRUG RESISTANCE, VIRAL; ENCEPHALITIS, HERPES SIMPLEX; HERPES SIMPLEX; HERPESVIRIDAE INFECTIONS; HUMANS; IMMUNOCOMPROMISED HOST; INFANT; INFANT, NEWBORN;

EID: 39149112786     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-73960-1_16     Document Type: Conference Paper

References (74)

1. Adler SP. (1985). The molecular epidemiology of cytomegalovirus transmission among children attending a day care center. J Infect Dis, 152:760-768.
2. Alpert G, Mazeron MC, and Colimon R, et al. (1985). Rapid detection of human cytomegalovirus in the urine of humans. J Infect Dis, 152:631-633.
3. American Academy of Pediatrics. (2003). Herpes simplex. In Pickering LK (eds.), Red Book: Report of the Committee on Infectious Diseases, 26th ed. Elk Grove Village, IL, American Academy of Pediatrics, pp. 344-353.
4. Anderson NE, Powell KF, and Croxson MC. (1993). A polymerase chain reaction assay of cerebrospinal fluid in patients with suspected herpes simplex encephalitis. J Neurol Neurosurg Psychiatry, 56:520-525.
5. Aurelius E, Johansson B, and Skoldenberg B, et al. (1991). Rapid diagnosis of herpes simplex encephalitis by nested polymerase chain reaction assay of cerebrospinal fluid. Lancet, 337:189-192.
6. Aurelius E, Johansson B, and Skoldenberg B, et al. (1993). Encephalitis in immunocompe-tent patients due to herpes simplex virus type 1 or 2 as determined by type-specific polymerase chain reaction and antibody assays of cerebrospinal fluid. J Med Virol, 39:179-186.
7. Balfour HH Jr., Bean B, and Laskin O, et al. (1983). Acyclovir halts progression of herpes zoster in immunocompromised patients. N Engl J Med, 308:1448-1453.
8. Barbi M, Binda S, and Primache V, et al. (1998). Use of Guthrie cards for the early diagnosis of neonatal herpes simplex virus disease. Pediatr Infect Dis J, 17:251-252.
9. Boppana SB, Pass RF, and Britt WJ, et al. (1992). Symptomatic congenital cytomegalovirus infection: neonatal morbidity and mortality. Pediatr Infect Dis J, 11:93-99.
10. Brown ZA, Vontver LA, and Benedetti J, et al. (1987). Effects on infants of a first episode of genital herpes during pregnancy. N Engl J Med, 317:1246-1251.
11. Brown ZA, Benedetti J, and Ashley R, et al. (1991). Neonatal herpes simplex virus infection in relation to asymptomatic maternal infection at the time of labor. N Engl J Med, 324: 1247-1252.
12. Brown ZA, Wald A, and Morrow RA, et al. (2003). Effect of serologic status and cesarean delivery on transmission rates of herpes simplex virus from mother to infant. JAMA, 289:203-209.
13. Conboy TJ, Pass RF, and Stagno S, et al. (1987). Early clinical manifestations and intellectual outcome in children with symptomatic congenital cytomegalovirus infection. J Pediatr, 111:343-348.
14. Corey L, and Wald A. (1999). Genital herpes. In Wasserheit JN, (eds.), Sexually Transmitted Diseases, third edn. McGraw-Hill, New York, NY, pp. 285-312.
15. Dahle AJ, Fowler KB, and Wright JD, et al. (2000). Longitudinal investigations of hearing disorders in children with congenital cytomegalovirus. J Am Acad Audiol, 11:283-290.
16. DeBiasi RL and Tyler KL. (1999). Polymerase chain reaction in the diagnosis and management of central nervous system infections. Arch Neurol, 56:1215-1219.
17. Demmler GJ. (1990). Infectious Diseases Society of America and Centers for Disease Control: summary of a workshop on surveillance for congenital cytomegalovirus disease. Rev Infect Dis, 13:315-329.
18. Demmler GJ, Buffone GJ, and Schimbor CM, et al. (1988). Detection of cytomegalovirus in urine from newborns by using polymerase chain reaction DNA amplification. J Infect Dis, 158:1177-1337.
19. Diamond C, Mohan K, and Hobson A, et al. (1999). Viremia in neonatal herpes simplex virus infections. Pediatr Infect Dis J, 18:487-489.
20. Dunkle LM, Arvin A, and Whitley RJ et al. (1991). A controlled trial of acyclovir for chickenpox in normal children. N Engl J Med, 325:1539-1544.
21. Fodor PA, Levin MJ, and Weinberg A, et al. (1998). Atypical herpes simplex virus encephalitis diagnosed by PCR amplification of viral DNA from CSF. Neurology, 51:554-559.
22. Fowler KB, McCollister FP, and Dahle AJ, et al. (1997). Progressive and fluctuating sensorineural hearing loss in children with asymptomatic congenital cytomegalovirus infection. J Pediatr, 130:624-630.
23. Gleaves CA, Smith TF, and Shuster EA, et al. (1984). Rapid detection of cytomegalovirus in MRC-5 cells inoculated with urine specimens by using low-speed centrifugation and monoclonal antibody to early antigen. J Clin Microbiol, 19:917-919.
24. Harris S, Ahlfors K, and Ivarsson SA, et al. (1984). Congenital cytomegalovirus infection and sensorineural hearing loss. Ear Hear, 5:352-355.
25. Hutto C, Ricks R, and Garvie M, et al. (1985). Epidemiology of cytomegalovirus infections in young children: day care vs. home care. Pediatr Infect Dis, 4:149-152.
26. Johnson RT, Olson LC, and Buescher EL, (1968). Herpes simplex virus infections of the nervous system: problems in laboratory diagnosis. Arch Neurol, 18:260-264.
27. Kimberlin DW, Kern ER, and Sidwell RW, et al. (1995). Models of antiviral resistance. Antiviral Res, 26:415-422.
28. Kimberlin DW, Lakeman FD, and Arvin AM, et al. (1996). Application of the polymerase chain reaction to the diagnosis and management of neonatal herpes simplex virus disease. J Infect Dis, 174:1162-1167.
29. Kimberlin DW, Lin CY, and Jacobs RF, et al. (2001a). Natural history of neonatal herpes simplex virus infections in the acyclovir era. Pediatrics, 108:223-229.
30. Kimberlin DW, Lin CY, and Jacobs RF, et al. (2001b). Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections. Pediatrics, 108:230-238.
31. Kimberlin DW, Lin CY, and Sanchez PJ et al. (2003). Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: a randomized, controlled trial. J Pediatr, 143:16-25.
32. Kimura H, Futamura M, Kito H, et al. (1991). Detection of viral DNA in neonatal herpes simplex infections: frequent and prolonged presence in serum and cerebrospinal fluid. J Infect Dis, 164:289-293.
33. Kimura H, Ito Y, Futamura M, et al. (2002). Quantitation of viral load in neonatal herpes simplex virus infection and comparison between type 1 and type 2. J Clin Virol, 67:349-353.
34. Kost RG, Hill EL, and Tigges M, et al. (1993). Brief report: recurrent acyclovir resistant genital herpes in an immunocompetent host. N Eng J Med, 329:1777-1781.
35. Lakeman FD, Whitley RJ, for the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. (1995). Diagnosis of herpes simplex encephalitis: application of polymerase chain reaction to cerebrospinal fluid from brain biopsied patients and correlation with disease. J Infect Dis, 172: 857-863.
36. Lewensohn-Fuchs I, Osterwall P, and Forsgren M, et al. (2003). Detection of herpes simplex virus DNA in dried blood spots making a retrospective diagnosis possible. J. Clin Virol, 26-39-48.
37. Littler E, Stuart AD, and Chee MS. (1992). Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir. Nature, 358:160-162.
38. Longson M. (1984). The general nature of viral encephalitis in the United Kingdom. In Ellis LS (eds.), Viral Diseases of the Central Nervous System. Bailliere Tindall, London, pp. 19-31.
39. Malm G, Forsgren M. (1999). Neonatal herpes simplex virus infections: HSV DNA in cerebrospinal fluid and serum. Arch Dis Childhood Fetal Neonatal Ed, 81:F24-F29.
40. Murph JR, Bale JF, and Perlman S. et al. (1985). The prevalence of cytomegalovirus infection in a Midwest day care center. Pediatr Res, 19:205A.
41. Nahmias AJ, Josey WE, and Naib ZM, et al. (1971). Perinatal risk associated with maternal genital herpes simplex virus infection. Am J Obstet Gynecol, 110:825-837.
42. Nahmias AJ, Whitley RJ, and Visintine AN, et al. (1982). Herpes simplex encephalitis: laboratory evaluations and their diagnostic significance. J Infect Dis, 145:829-836.
43. Nyerges G, Meszner Z, and Gyormati E et al. (1988). Acyclovir prevents dissemination of varicella in immunocompromised children. J Infect Dis, 157:309-313.
44. Oliver S, Cloud G, Sánchez P, Demmler G, Dankner W, Shelton M, Jacobs R, Vaudry W, Pass R, Soong S, Whitley R, and Kimberlin D. (2006). Effect of Ganciclovir (GCV) Therapy on Neurodevelopmental Outcomes in Symptomatic Congenital Cytomegalovirus (CMV) Infections Involving the Central Nervous System(CNS): A Randomized, Controlled Study. Society for Pediatric Research (SPR). San Francisco, CA, April 29, Abstract #752908.
45. Pass RF. (2001). Cytomegalovirus. In Knipe DM, and Howley PM (eds): Fields Virology (ed 4). Lippincott Williams & Wilkins, Philadelphia, PA, pp. 2675-2705.
46. Prober CG, Kirk LE, and Keeney RE, et al. (1982). Acyclovir therapy of chickenpox in immuno-suppressed children-a collaborative study. J Pediatr, 101:622-625.
47. Puchhammer-Stockl E, Heinz FX, and Kundi M, et al. (1993). Evaluation of the polymerase chain reaction for diagnosis of herpes simplex virus encephalitis. J Clin Microbiol, 31: 146-148.
48. Rivera LB, Boppana SB, and Fowler KB, et al. (2002). Predictors of hearing loss in children with symptomatic congenital cytomegalovirus infection. Pediatrics, 110:762-767.
49. Rowley A, Lakeman F, and Whitley R, et al. (1990). Rapid detection of herpes simplex virus DNA in cerebrospinal fluid of patients with herpes simplex encephalitis. Lancet, 335:440-441.
50. Sakrauski A, Weber B Kessler HH, et al. (1994). Comparison of two hybridization assays for the rapid detection of PCR amplified HSV genome sequences from cerebrospinal fluid. J Virol Methods, 50:175-184.
51. Schlesinger Y, Storch GA. (1994). Herpes simplex meningitis in infancy. Pediatr Infect Dis, 13:141-144.
52. Shoji H, Koga M, and Kusuhara T, et al. (1994). Differentiation of herpes simplex virus 1 and 2 in cerebrospinal fluid of patients with HSV encephalitis and meningitis by stringent hybridization of PCR-amplified DNAs. J Nenrol, 241:526-530.
53. Skoldenberg B, Forsgren M, Alestig K, et al. (1984). Acyclovir versus vidarabine in herpes simplex encephalitis: a randomized multicenter study in consecutive Swedish patients. Lancet, 2:707-711.
54. Stagno S, Pass RF, and Dworkin ME, et al. (1982). Congenital cytomegalovirus infection: The relative importance of primary and recurrent maternal infection. N Engl J Med, 306:945-949.
55. Sullivan V, Talarico CL, and Stanat SC, et al. (1992). A protein kinase homolog controls phosphorylation of ganciclovir in human cytomegalovirus- infected cells. Nature, 358:162-164.
56. Trang JM, Kidd L, and Gruber W, et al., and the NIAID Collaborative Antiviral Study Group. (1993). Linear single-dose pharmacokinetics of ganciclovir in newborns with congenital cytomegalovirus infections. Clin Pharmacol Ther, 53:15-21.
57. Troendle-Atkins J, Demmler GJ, and Buffone GJ. (1993). Rapid diagnosis of herpes simplex virus encephalitis by using the polymerase chain reaction. J Pediatr, 123:376-380.
58. Van Landingham KE, Marsteller HB, and Ross GW, et al. (1988). Relapse of herpes simplex encephalitis after conventional acyclovir therapy. JAMA, 259:1051-1053.
59. Wallace MR, Bowler WA, and Murray NB. (1992). Treatment of adult varicella with oral acyclovir. A randomized, placebo-controlled trial. Ann Intern Med, 117:358-363.
60. Wang HS, Kuo MF, and Huang SC, et al. (1994). Choreoathetosis as an initial sign of relapsing of herpes simplex encephalitis. Pediatr Neurol, 11:341-345.
61. Warren WP, Balcarek KB, and Smith R, et al. (1992). Comparison of rapid methods of detection of cytomegalovirus in saliva with virus isolation in tissue culture. J Clin Microbiol, 30:786-789.
62. Whitley RJ, Yeager A, and Kartus P, et al. (1983). Neonatal herpes simplex virus infection: follow-up evaluation of vidarabine therapy. Pediatrics, 72:778-785.
63. Whitley RJ, Soong S-J, and Dolin R, et al. (1977). Adenine arabinoside therapy of biopsy-proved herpes simplex encephalitis: National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study. N Engl J Med, 297:289-294.
64. Whitley RJ, Nahmias AJ, and Soong SJ, et al. (1980). Vidarabine therapy of neonatal herpes simplex virus infection. Pediatrics, 66:495-501.
65. Whitley RJ, Soong S-J, and Hirsch MS, et al. (1981). Herpes simplex encephalitis: vidarabine therapy and diagnostic problems. N Engl J Med, 304:313-318.
66. Whitley RJ, Yeager A, and Kartus P, et al. (1983). Neonatal herpes simplex virus infection: follow-up evaluation of vidarabine therapy. Pediatrics, 72:778-785.
67. Whitley RJ, Alford CA Jr, and Hirsch MS, et al. (1986). Vidarabine versus acyclovir therapy in herpes simplex encephalitis. N Engl J Med, 314:144-149.
68. Whitley R, Arvin A, and Prober C, et al. (1991a). A controlled trial comparing vidarabine with acyclovir in neonatal herpes simplex virus infection. N Engl J Med, 324:444-449.
69. Whitley R, Arvin A, and Prober C, et al. (1991b). Predictors of morbidity and mortality in neonates with herpes simplex virus infections. N Engl J Med, 324:450-454.
70. Whitley RJ, Cloud G, Gruber W, et al., and the NIAID Collaborative Antiviral Study Group. (1997). Ganciclovir treatment of symptomatic congenital cytomegalovirus infection: results of a phase II study. J Infect Dis, 175:1080-1086.
71. Whitley RMD, Davis E Pharm D, MS, and Suppapanya N. Incidence of neonatal herpes simplex virus infections in a managed-care population. Submitted to American Journal of Public Health.
72. Williamson WD, Desmond MM, and LaFevers N, et al. (1982). Symptomatic congenital cytome-galovirus. Disorders of language, learning and hearing. Am J Dis Child, 136:902-905.
73. Williamson WD, Demmler GJ, and Percy AK, et al. (1992). Progressive hearing loss in infants with asymptomatic congenital cytomegalovirus infection. Pediatrics, 90:862-866.
74. Zhou XJ, Gruber W, and Demmler G, et al., and the NIAID Collaborative Antiviral Study Group. (1996). Population pharmacokinetics of ganciclovir in newborns with congenital cytomegalovirus infections. Antimicrob Agents Chemother, 40:2202-2205.