-
1
-
-
18244377969
-
Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia
-
Kreda, S.M. et aL. Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia. MoL. BioL. CeLL 16, 2154-2167 (2005).
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 2154-2167
-
-
Kreda, S.M.1
-
2
-
-
0028210022
-
Expression of the cystic fibrosis gene in adult human lung
-
Engelhardt, J.F., Zepeda, M., Cohn, J.A., Yankaskas, J.R. & Wilson, J.M. Expression of the cystic fibrosis gene in adult human lung. J. CLin. Invest. 93, 737-749 (1994).
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 737-749
-
-
Engelhardt, J.F.1
Zepeda, M.2
Cohn, J.A.3
Yankaskas, J.R.4
Wilson, J.M.5
-
3
-
-
0032718592
-
Airway epithelia CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus
-
Harvey, B.G. et aL. Airway epithelia CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus. J. CLin. Invest. 104, 1245-1255 (1999).
-
(1999)
J. Clin. Invest
, vol.104
, pp. 1245-1255
-
-
Harvey, B.G.1
-
4
-
-
0028979810
-
Aerosol delivery of a beta-galactosidase adenoviral vector to the lungs of rodents
-
Katkin, J.P., Gilbert, B.E., Langston, C., French, K. & Beaudet, A.L. Aerosol delivery of a beta-galactosidase adenoviral vector to the lungs of rodents. Hum. Gene Ther. 6, 985-995 (1995).
-
(1995)
Hum. Gene Ther
, vol.6
, pp. 985-995
-
-
Katkin, J.P.1
Gilbert, B.E.2
Langston, C.3
French, K.4
Beaudet, A.L.5
-
5
-
-
0346571517
-
Aerosol-mediated delivery of recombinant adenovirus to the airways of non-human primates
-
Sene, C. et aL. Aerosol-mediated delivery of recombinant adenovirus to the airways of non-human primates. Hum. Gene Ther. 6, 1587-1593 (1995).
-
(1995)
Hum. Gene Ther
, vol.6
, pp. 1587-1593
-
-
Sene, C.1
-
6
-
-
0033005285
-
Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors
-
Li, S. et aL. Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors. Am. J. PhysioL. 276, L796-L804 (1999).
-
(1999)
Am. J. Physiol
, vol.276
, pp. L796-L804
-
-
Li, S.1
-
7
-
-
0034219238
-
Vivo gene delivery to the lung using polyethylenimine and fractured polyamidoamine dendrimers
-
Rudolph, C., Lausier, J., Naundorf, S., Müller, R.H. & Rosenecker, J. In vivo gene delivery to the lung using polyethylenimine and fractured polyamidoamine dendrimers. J. Gene Med. 2, 269-278 (2000).
-
(2000)
J. Gene Med
, vol.2
, pp. 269-278
-
-
Rudolph, C.1
Lausier, J.2
Naundorf, S.3
Müller, R.H.4
Rosenecker, J.5
-
8
-
-
0031720533
-
Polyethylenimine-based intravenous delivery of transgenes to mouse lung
-
Goula, D. et aL. Polyethylenimine-based intravenous delivery of transgenes to mouse lung. Gene Ther. 5, 1291-1295 (1998).
-
(1998)
Gene Ther
, vol.5
, pp. 1291-1295
-
-
Goula, D.1
-
9
-
-
85044710228
-
Polyethylenimine (PEI)
-
Demeneix, B. & Behr, J.P. Polyethylenimine (pEI). Adv. Genet. 53, 217-230 (2000).
-
(2000)
Adv. Genet
, vol.53
, pp. 217-230
-
-
Demeneix, B.1
Behr, J.P.2
-
10
-
-
0033394513
-
Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs
-
Bragonzi, A. etaL. Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs. Gene Ther. 6, 1995-2004 (1999).
-
(1999)
Gene Ther
, vol.6
, pp. 1995-2004
-
-
Bragonzi, A.1
-
11
-
-
0030662074
-
Molecular reconstruction of SLeeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells
-
Ivics, Z., Hackett, P.B., Plasterk, R.H. & Izsvak, Z. Molecular reconstruction of SLeeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells. CeLL 91, 501-510 (1997).
-
(1997)
Cell
, vol.91
, pp. 501-510
-
-
Ivics, Z.1
Hackett, P.B.2
Plasterk, R.H.3
Izsvak, Z.4
-
12
-
-
0034705105
-
Phage integrase directs efficient site-specific integration in human cells
-
Groth, A., Olivares, E.C., Thyagarajan, B. & Calos, M.P. A phage integrase directs efficient site-specific integration in human cells. Proc. NatL. Acad. Sci. USA. 97, 5995-6000 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5995-6000
-
-
Groth, A.1
Olivares, E.C.2
Thyagarajan, B.3
Calos, M.4
-
13
-
-
1542397137
-
Phage integrases: Biology and applications
-
Groth, A. & Calos, M.P. Phage integrases: biology and applications. J. MoL. BioL. 335, 667-678 (2004).
-
(2004)
J. Mol. Biol
, vol.335
, pp. 667-678
-
-
Groth, A.1
Calos, M.P.2
-
14
-
-
0242334000
-
Efficientgene delivery and gene expression in zebrafish using the SLeeping Beauty transposon
-
Davidson, A.E. etaL. Efficientgene delivery and gene expression in zebrafish using the SLeeping Beauty transposon. Dev. BioL. 263, 191-202 (2003).
-
(2003)
Dev. Biol
, vol.263
, pp. 191-202
-
-
Davidson, A.E.1
-
15
-
-
4444339395
-
Transposon vectors for gene-trap insertional mutagenesis in vertebrates
-
Clark, K.J., Geurts, A.M., Bell, J.B. & Hackett, P.B. Transposon vectors for gene-trap insertional mutagenesis in vertebrates. Genesis 39, 225-233 (2004).
-
(2004)
Genesis
, vol.39
, pp. 225-233
-
-
Clark, K.J.1
Geurts, A.M.2
Bell, J.B.3
Hackett, P.B.4
-
16
-
-
23944452046
-
Fishing foranswers with transposons. Mar
-
Wadman, S.A., Clark, K.J. & Hackett, P.B. Fishing foranswers with transposons. Mar. BiotechnoL. 7, 135-141 (2005).
-
(2005)
Biotechnol
, vol.7
, pp. 135-141
-
-
Wadman, S.A.1
Clark, K.J.2
Hackett, P.B.3
-
17
-
-
0037007139
-
Mammalian germ-line transgenesis by transposition
-
Dupuy, A.J. et aL. Mammalian germ-line transgenesis by transposition. Proc. NatL. Acad. Sci. USA. 99, 4495-4499 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 4495-4499
-
-
Dupuy, A.J.1
-
18
-
-
0034964286
-
Transposition and gene disruption in the male germline of the mouse
-
Dupuy, A.J., Fritz, S. & Largaespada, D.A. Transposition and gene disruption in the male germline of the mouse. Genesis 30, 82-88 (2001).
-
(2001)
Genesis
, vol.30
, pp. 82-88
-
-
Dupuy, A.J.1
Fritz, S.2
Largaespada, D.A.3
-
19
-
-
0035810931
-
Regulated transposition ofa fish transposon in the mouse germ line
-
Fischer, S.E., Wienholds, E. & Plasterk, R.H. Regulated transposition ofa fish transposon in the mouse germ line. Proc. NatL. Acad. Sci. USA. 98, 6759-6764 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 6759-6764
-
-
Fischer, S.E.1
Wienholds, E.2
Plasterk, R.H.3
-
20
-
-
0035979255
-
Efficient chromosomal transposition ofa Tc1/mariner-like transposon SLeeping Beauty in mice
-
Horie, K etaL. Efficient chromosomal transposition ofa Tc1/mariner-like transposon SLeeping Beauty in mice. Proc. NatL. Acad. Sci. USA. 98, 9191-9196 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9191-9196
-
-
Horie, K.1
-
21
-
-
10744231615
-
Characterization of SLeeping Beauty transposition and its application to genetic screening in mice
-
Horie, K. etaL. Characterization of SLeeping Beauty transposition and its application to genetic screening in mice. MoL. CeLL. BioL. 23, 9189-9207 (2003).
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 9189-9207
-
-
Horie, K.1
-
22
-
-
30444432097
-
Stable gene transfer and expression in human primary T cells by the SLeeping Beauty transposon system
-
Huang, X. et aL. Stable gene transfer and expression in human primary T cells by the SLeeping Beauty transposon system. BLood 107, 483-491 (2006).
-
(2006)
Blood
, vol.107
, pp. 483-491
-
-
Huang, X.1
-
23
-
-
0141744705
-
Gene insertion and long-term expression in lung mediated by the SLeeping Beauty transposon system
-
Belur, L.R. etaL. Gene insertion and long-term expression in lung mediated by the SLeeping Beauty transposon system. MoL. Ther. 8, 501-507 (2003).
-
(2003)
Mol. Ther
, vol.8
, pp. 501-507
-
-
Belur, L.R.1
-
24
-
-
3042712919
-
Endothelialtargeting ofthe SLeeping Beauty transposon within lung
-
Liu, L. etaL. Endothelialtargeting ofthe SLeeping Beauty transposon within lung. MoL. Ther. 10, 97-105 (2004).
-
(2004)
Mol. Ther
, vol.10
, pp. 97-105
-
-
Liu, L.1
-
25
-
-
33845599867
-
Sleeping Beauty-based gene therapy with indoleamine 2,3-dioxygenase inhibits lung allograft fibrosis
-
Liu, H., Liu, L., Fletcher, B.S. & Visner, G.A. Sleeping Beauty-based gene therapy with indoleamine 2,3-dioxygenase inhibits lung allograft fibrosis. FASEB J. 13, 2384-2386 (2006).
-
(2006)
FASEB J
, vol.13
, pp. 2384-2386
-
-
Liu, H.1
Liu, L.2
Fletcher, B.S.3
Visner, G.A.4
-
26
-
-
33645882508
-
Sustained FVIII expression and phenotypic correction of hemophilia A in neonatal mice using an endothelial-targeted sleeping beauty transposon
-
Liu, L., Mah, C. & Fletcher, B.S. Sustained FVIII expression and phenotypic correction of hemophilia A in neonatal mice using an endothelial-targeted sleeping beauty transposon. Mol. Ther. 13,1006-1015 (2006).
-
(2006)
Mol. Ther
, vol.13
, pp. 1006-1015
-
-
Liu, L.1
Mah, C.2
Fletcher, B.S.3
-
27
-
-
0034103009
-
Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system
-
Yant, S.R. et al. Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system. Nat. Genet. 25, 35-41 (2000).
-
(2000)
Nat. Genet
, vol.25
, pp. 35-41
-
-
Yant, S.R.1
-
28
-
-
0036789403
-
Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo
-
Yant, S.R etal. Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo. Nat. Biotechnol. 20, 999-1005 (2002).
-
(2002)
Nat. Biotechnol
, vol.20
, pp. 999-1005
-
-
Yant, S.R.1
-
29
-
-
32944458256
-
Sleeping Beauty-mediated transposition and long-term expression in vivo: Use of the LoxP/Cre recombinase system to distinguish transposition-specific expression
-
Score, P.R. et al. Sleeping Beauty-mediated transposition and long-term expression in vivo: use of the LoxP/Cre recombinase system to distinguish transposition-specific expression. Mol. Ther. 13, 617-624 (2006).
-
(2006)
Mol. Ther
, vol.13
, pp. 617-624
-
-
Score, P.R.1
-
30
-
-
32944463921
-
RNA as a source of transposase for Sleeping Beauty-mediated gene insertion and expression in somatic cells and tissues. Mol
-
Wilber, A.C. et al. RNA as a source of transposase for Sleeping Beauty-mediated gene insertion and expression in somatic cells and tissues. Mol. Ther. 13,625-630(2006).
-
(2006)
Ther
, vol.13
, pp. 625-630
-
-
Wilber, A.C.1
-
31
-
-
20144386644
-
Phenotypic correction and long-term expression offactor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system
-
Ohlfest, J.R. etal. Phenotypic correction and long-term expression offactor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system. Blood 105, 2691-2698 (2005).
-
(2005)
Blood
, vol.105
, pp. 2691-2698
-
-
Ohlfest, J.R.1
-
32
-
-
27744497800
-
Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the Sleeping Beauty transposon causes tumor regression and improvessurvivalin mice bearing intracranial human glioblastoma
-
Ohlfest, J.R. et al. Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the Sleeping Beauty transposon causes tumor regression and improvessurvivalin mice bearing intracranial human glioblastoma. Mol. Ther. 12, 778-788 (2005).
-
(2005)
Mol. Ther
, vol.12
, pp. 778-788
-
-
Ohlfest, J.R.1
-
33
-
-
0042700227
-
Gene transfer into genomes of human cells by the Sleeping Beauty transposon system
-
Geurts, A.M. etal. Gene transfer into genomes of human cells by the Sleeping Beauty transposon system. Mol. Ther. 8, 108-117 (2003).
-
(2003)
Mol. Ther
, vol.8
, pp. 108-117
-
-
Geurts, A.M.1
-
34
-
-
0142213094
-
Helper-independent Sleeping Beauty transposon- transposase vectors for efficient nonviral gene delivery and persistent gene expression in vivo
-
Mikkelsen, J.G. et al. Helper-independent Sleeping Beauty transposon- transposase vectors for efficient nonviral gene delivery and persistent gene expression in vivo. Mol. Ther. 8, 654-665 (2003).
-
(2003)
Mol. Ther
, vol.8
, pp. 654-665
-
-
Mikkelsen, J.G.1
-
35
-
-
33846023389
-
Integrating DNA vectors for gene therapy
-
Hackett, P.B. Integrating DNA vectors for gene therapy. Mol. Ther. 15, 10-12(2007).
-
(2007)
Mol. Ther
, vol.15
, pp. 10-12
-
-
Hackett, P.B.1
-
36
-
-
25144492340
-
Sleeping Beauty transposon-mediated gene therapy for prolonged expression
-
Hackett, P.B., Ekker, S.C., Largaespada, D.L. & McIvor, R.S. Sleeping Beauty transposon-mediated gene therapy for prolonged expression. Adv. Genet. 54, 189-232 (2005).
-
(2005)
Adv. Genet
, vol.54
, pp. 189-232
-
-
Hackett, P.B.1
Ekker, S.C.2
Largaespada, D.L.3
McIvor, R.S.4
-
37
-
-
24344495491
-
Awakening gene therapy with Sleeping Beauty transposons
-
Essner, J.J., McIvor, R.S. & Hackett, P.B. Awakening gene therapy with Sleeping Beauty transposons. Curr. Opin. Pharmacol. 5, 513-519 (2005).
-
(2005)
Curr. Opin. Pharmacol
, vol.5
, pp. 513-519
-
-
Essner, J.J.1
McIvor, R.S.2
Hackett, P.B.3
-
38
-
-
33749536744
-
Transposons for gene therapy
-
Ivics, Z. & Izsvak, Z. Transposons for gene therapy! Curr. Gene Ther. 6, 593-607 (2006).
-
(2006)
Curr. Gene Ther
, vol.6
, pp. 593-607
-
-
Ivics, Z.1
Izsvak, Z.2
-
39
-
-
39149118329
-
Preferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injection
-
Bell, J.B. et al. Preferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injection. Nat. Protoc. 2, 3153-3165 (2007).
-
(2007)
Nat. Protoc
, vol.2
, pp. 3153-3165
-
-
Bell, J.B.1
-
40
-
-
84988044416
-
Rats and mice
-
(eds. Laber-Laird, K., Swindle, M.M., & Flecknell, P., Pergamon Veterinary Handbook Series, Tarrytown, NY
-
Fallon, M. Rats and mice. In Handbook ofRodent and RabbitMedicine 1st edn (eds. Laber-Laird, K., Swindle, M.M., & Flecknell, P.) 9-11 (Pergamon Veterinary Handbook Series, Tarrytown, NY, 1996).
-
(1996)
Handbook Ofrodent and Rabbitmedicine 1St Edn
, pp. 9-11
-
-
Fallon, M.1
-
41
-
-
0036932834
-
Vivo correction ofmurine tyrosinemia type I by DNA-mediated transposition
-
Montini, E. etal. In vivo correction ofmurine tyrosinemia type I by DNA-mediated transposition. Mol. Ther. 6, 759-769 (2002).
-
(2002)
Mol. Ther
, vol.6
, pp. 759-769
-
-
Montini, E.1
|