Distribution and antibacterial susceptibility of macrolide resistance genotypes in Streptococcus pneumoniae: PROTEKT Year 5 (2003-2004)

International Journal of Antimicrobial Agents

Volumn 31, Issue 3, 2008, Pages 245-249

  Farrell, David J ^a   Couturier, Catherine ^b   Hryniewicz, Waleria ^c  

^a GR Micro Ltd   (United Kingdom)

^b SANOFI   (France)

^c NATIONAL MEDICINES INSTITUTE   (Poland)

Author keywords

Community acquired pneumonia; Genotyping; Macrolide resistance; PROTEKT; Streptococcus pneumoniae; Surveillance

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; AZITHROMYCIN; CEFUROXIME; CLARITHROMYCIN; COTRIMOXAZOLE; ERYTHROMYCIN; LEVOFLOXACIN; MACROLIDE; PENICILLIN G; TELITHROMYCIN; TETRACYCLINE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; GENOTYPE; HOSPITAL ADMISSION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; STREPTOCOCCUS PNEUMONIAE;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAM RESISTANCE; CHILD; CHILD, PRESCHOOL; COMMUNITY-ACQUIRED INFECTIONS; DRUG RESISTANCE, BACTERIAL; HUMANS; INFANT; INFANT, NEWBORN; MACROLIDES; MEMBRANE PROTEINS; METHYLTRANSFERASES; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; PNEUMOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE; TETRACYCLINE RESISTANCE;

EID: 39149101446     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2007.10.022     Document Type: Article

References (16)

1. Halpern M.T., Schmier J.K., Snyder L.M., Asche C., Sarocco P.W., Lavin B., et al. Meta-analysis of bacterial resistance to macrolides. J Antimicrob Chemother 55 (2005) 748-757
2. Schito G.C. Resistance trends in Streptococcus pneumoniae (PROTEKT years 1-3 [1999-2002]). J Chemother 16 Suppl. 6 (2004) 19-33
3. Daneman N., McGeer A., Green K., and Low D.E. Macrolide resistance in bacteremic pneumococcal disease: implications for patient management. Clin Infect Dis 43 (2006) 432-438
4. Klugman K.P., and Lonks J.R. Hidden epidemic of macrolide-resistant pneumococci. Emerg Infect Dis 11 (2005) 802-807
5. Edelstein P.H. Pneumococcal resistance to macrolides, lincosamides, ketolides, and streptogramin B agents: molecular mechanisms and resistance phenotypes. Clin Infect Dis 38 Suppl. 4 (2004) S322-S327
6. Felmingham D. The need for antimicrobial resistance surveillance. J Antimicrob Chemother 50 Suppl. S1 (2002) 1-7
7. Farrell D.J., Jenkins S.G., Brown S.D., Patel M., Lavin B.S., and Klugman K.P. Emergence and spread of Streptococcus pneumoniae with erm(B) and mef(A) resistance. Emerg Infect Dis 11 (2005) 851-858
8. Farrell D.J., Klugman K.P., and Pichicero M. Increased antimicrobial resistance among non-vaccine serotypes of Streptococcus pneumoniae in the pediatric population following the introduction of PCV7 in the USA. Pediatr Infect Dis J 26 (2007) 123-128
9. Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard. Document M7-A7. Wayne, PA: CLSI; 2006.
10. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing. Sixteenth informational supplement. Document M100-S16. Wayne, PA: CLSI; 2006.
11. Shackcloth J., Williams L., and Farrell D.J. Streptococcus pneumoniae and Streptococcus pyogenes isolated from a paediatric population in Great Britain and Ireland: the in vitro activity of telithromycin versus comparators. J Infect 48 (2004) 229-235
12. Farrell D.J., Douthwaite S., Morrissey I., Bakker S., Poehlsgaard J., Jakobsen L., et al. Macrolide resistance by ribosomal mutation in clinical isolates of Streptococcus pneumoniae from the PROTEKT 1999-2000 study. Antimicrob Agents Chemother 47 (2003) 1777-1783
13. Farrell D.J., Morrissey I., Bakker S., Morris L., Buckridge S., and Felmingham D. Molecular epidemiology of multiresistant Streptococcus pneumoniae with both erm(B)- and mef(A)-mediated macrolide resistance. J Clin Microbiol 42 (2004) 764-768
14. Ko K.S., and Song J.H. Evolution of erythromycin-resistant Streptococcus pneumoniae from Asian countries that contains erm(B) and mef(A) genes. J Infect Dis 190 (2004) 739-747
15. Hsu K.K., and Pelton S.I. Heptavalent pneumococcal conjugate vaccine: current and future impact. Expert Rev Vaccines 2 (2003) 619-631
16. Beall B., McEllistrem M.C., Gertz Jr. R.E., Wedel S., Boxrud D.J., Gonzalez A.L., et al. Pre- and postvaccination clonal compositions of invasive pneumococcal serotypes for isolates collected in the United States in 1999, 2001, and 2002. J Clin Microbiol 44 (2006) 999-1017