Modeling and assaying dioxin-like biological effects for both dioxin-like and certain non-dioxin-like compounds

Toxicological Sciences

Volumn 102, Issue 1, 2008, Pages 187-195

  Wilkes, Jon G ^a,c   Hass, Bruce S ^a   Buzatu, Dan A ^a   Pence, Lisa M ^a   Archer, Jeffrey C ^a   Beger, Richard D ^a   Schnackenberg, Laura K ^a   Halbert, Mary Kim ^a   Jennings, Lisa ^a   Kodell, Ralph I ^b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Biological modeling; Dioxin; Polychlorinated biphenyls; QSAR; Regulatory policy

Indexed keywords

1,2,3,4,7 PENTACHLORODIBENZO 1,4 DIOXIN; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 2,3,7,8 TETRACHLOROPHENOTHIAZINE; DIOXIN; FURAN; LUCIFERASE; PHENOTHIAZINE DERIVATIVE; POLYCHLORINATED BIPHENYL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COMPUTER MODEL; CONTROLLED STUDY; CORRELATION ANALYSIS; FOOD CONTAMINATION; GENE EXPRESSION; IN VITRO STUDY; LIVER CELL; MODEL; MOUSE; NONHUMAN; PREDICTION; RISK ASSESSMENT; TOXICITY;

ANIMALS; BIOLOGICAL ASSAY; CELL LINE; DIOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FURANS; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; POLYCHLORINATED BIPHENYLS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, ARYL HYDROCARBON; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; TOXICITY TESTS; TRANSFECTION;

EID: 39149095953     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm294     Document Type: Article

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