Strategic studies in the syntheses of novel 6,7-substituted quinolones and 7- or 6-substituted 1,6- and 1,7-naphthyridones

Tetrahedron

Volumn 64, Issue 12, 2008, Pages 2772-2782

  Morgentin, Rémy ^a   Pasquet, Georges ^a   Boutron, Pascal ^a   Jung, Frédéric ^a   Lamorlette, Maryannick ^a   Maudet, Mickaël ^a   Plé, Patrick ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Naphthyridone; Quinolone; Regioselectivity; Strategy

Indexed keywords

1H 1,7 NAPHTHYRIDIN 4 ONE; 2,2 DIMETHYL 5 [[(1 OXIDOPYRIDIN 3 YL)AMINO]METHYLIDENE] 1,3 DIOXANE 4,6 DIONE; 4 OXO 1H QUINOLINE 7 CARBOXYLIC ACID; 5 [[(2 CHLORO 6 METHOXYPYRIDIN 3 YL)AMINO]METHYLIDENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [[(2 CHLOROPYRIDIN 3 YL)AMINO]METHYLIDENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [[(2 METHOXYPYRIDIN 4 YL)AMINO]METHYLIDENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [[(2,6 DICHLOROPYRIDIN 4 YL)AMINO]METHYLIDENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [[(3 BROMO 2 METHOXYPYRIDIN 4 YL)AMINO]METHYLIDENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [[(3 METHOXYPHENYL)AMINO]METHYLIDENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [[(6 METHOXYPYRIDIN 3 YL)AMINO]METHYLIDENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 METHOXY 1H 1,6 NAPHTHYRIDIN 4 ONE; 5 METHOXY 1H QUINOLIN 4 ONE; 5,7 DICHLORO 1H 1,6 NAPHTHYRIDIN 4 ONE; 6 METHOXY 1H 1,7 NAPHTHYRIDIN 4 ONE; 7 CHLORO 1H 1,6 NAPHTHYRIDIN 4 ONE; 7 METHOXY 1H 1,6 NAPHTHYRIDIN 4 ONE; 7 METHOXY 1H QUINOLIN 4 ONE; 7 METHOXY 1H QUINOLINE 4 ONE; 8 BROMO 7 METHOXY 1H 1,6 NAPHTHYRIDIN 4 ONE; METHYL 2 CHLORO 3 [(2,2 DIMETHYL 4,6 DIOXO 1,3 DIOXAN 5 YLIDENE)METHYLAMINO]BENZOIC ACID; METHYL 3 [(2,2 DIMETHYL 4,6 DIOXO 1,3 DIOXAN 5 YLIDENE)METHYLAMINO]BENZOIC ACID; METHYL 4 OXO 1H QUINOLINE 7 CARBOXYLIC ACID; METHYL 5 [(2,2 DIMETHYL 4,6 DIOXO 1,3 DIOXAN 5 YLIDENE)METHYLAMINO] 2 METHOXYBENZOIC ACID; METHYL 6 METHOXY 4 OXO 1H QUINOLINE 7 CARBOXYLIC ACID; METHYL 8 CHLORO 4 OXO 1H QUINOLINE 7 CARBOXYLIC ACID; NAPHTHYRIDINE DERIVATIVE; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; DECARBOXYLATION; DEHALOGENATION; ISOMERISM; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SAPONIFICATION;

EID: 39149090316     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.01.055     Document Type: Article

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