Effects of 6-(methylsulfinyl)hexyl isothiocyanate on cyclooxygenase-2 expression induced by lipopolysaccharide, interferon-γ and 12-O-tetradecanoylphorbol-13-acetate

Oncology Reports

Volumn 17, Issue 1, 2007, Pages 233-238

  Uto, Takuhiro ^a   Fujii, Makoto ^a   Hou, De Xing ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

12 O tetradecanoylphorbol 13 acetate; 6 (methylsulfinyl)hexyl isothiocyanate; Cyclooxygenase 2; Interferon ; Lipopolysaccharide; Macrophages

Indexed keywords

6 (METHYLSULFINYL)HEXYL ISOTHIOCYANATE; 6-(METHYLSULFINYL)HEXYL ISOTHIOCYANATE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; GAMMA INTERFERON; ISOTHIOCYANIC ACID DERIVATIVE; LIPOPOLYSACCHARIDE; PHORBOL 13 ACETATE 12 MYRISTATE; TRANSCRIPTION FACTOR;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; DRUG INTERACTION; ENZYME INDUCTION; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; MACROPHAGE; METABOLISM; MOUSE; PROMOTER REGION;

ANIMALS; CELL LINE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DRUG INTERACTIONS; ENZYME INDUCTION; INTERFERON TYPE II; ISOTHIOCYANATES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; PROMOTER REGIONS (GENETICS); TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 39049193327     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.17.1.233     Document Type: Article

References (34)

1. Murillo G and Mehta RG: Cruciferous vegetables and cancer prevention. Nutr Cancer 41: 17-28, 2001. (Pubitemid 34666216)
2. Zhang Y: Cancer-preventive isothiocyanates: measurement of human exposure and mechanism of action. Mutat Res 555: 173-190, 2004.
3. Fuke Y, Haga Y, Ono H, Nomura T and Ryoyama K: Anticarcinogenic activity of 6-methylsulfinylhexyl isothiocyanates (6-MITC), and an active antiproliferative principal of wasabi (Eutrema wasabi Maxim.). Cytotechnology 25: 197-203, 1997. (Pubitemid 28110880)
4. Yano T, Yajima S, Virgona N, Yano Y, Otani S, Kumagai H, Sakurai H, Kishimoto M and Ichikawa T: The effect of 6-methylthiohexyl isothiocyanate isolated from Wasabia japonica (wasabi) on 4-(methylnitrosamino)-1-(3-pyridyl)- 1-buatnone-induced lung tumorigenesis in mice. Cancer Lett 155: 115-120, 2000. (Pubitemid 30259124)
5. Nomura T, Shinoda S, Yamori T, Sawaki S, Nagata I, Ryoyama K and Fuke Y: Selective sensitivity to wasabi-derived 6-(methylsulfinyl)hexyl isothiocyanate of human breast cancer and melanoma cell lines studied in vitro. Cancer Detect Prev 29: 155-160, 2005.
6. Funk CD, Funk LB, Kennedy ME, Pong AS and Fitzgerald GA: Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment. FASEB J 5: 2304-2312, 1991. (Pubitemid 21892908)
7. Hempel SL, Monick MM and Hunninghake GW: Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes. J Clin Invest 93: 391-396, 1994. (Pubitemid 24030860)
8. Crofford LJ, Wilder RL, Ristimaki AP, Sano H, Remmers EF, Epps HR and Hla T: Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids. J Clin Invest 93: 1095-1101, 1994.
9. Rolland PH, Martin PM, Jacquemier J, Rolland AM and Toga M: Prostaglandin in human breast cancer: evidence suggesting that an elevated prostaglandin production is a marker of high metastatic potential for neoplastic cells. J Natl Cancer Inst 64: 1061-1070, 1980. (Pubitemid 10100318)
10. Lupulescu A: Prostaglandins, their inhibitors and cancer. Prostaglandins Leukot Essent Fatty Acids 54: 83-94, 1996.
11. Sheng H, Shao J, Morrow JD, Beauchamp RD and DuBois RN: Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Res 58: 362-366, 1998. (Pubitemid 28047080)
12. Ben-Av P, Crofford LJ, Wilder RL and Hla T: Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin-1: a potential mechanism for inflammatory angiogenesis. FEBS Lett 372: 83-87, 1997.
13. Goodwin JS and Ceuppens J: Regulation of the immune response by prostaglandins. J Clin Immunol 3: 295-314, 1983.
14. Tsujii M and DuBois RN: Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 83: 493-501, 1995.
15. Tanabe T and Tohnai N: Cyclooxygenase isozymes and their gene structures and expression. Prostaglandins Other Lipid Mediat 68-69: 95-114, 2002. (Pubitemid 35247390)
16. Hou D-X, Kai K, Li JJ, Lin S, Terahara N, Wakamatsu M, Fujii M, Young MR and Colburn N: Anthocyanidins inhibit activator protein 1 activity and cell transformation: structure-activity relationship and molecular mechanisms. Carcinogenesis 25: 29-36, 2004. (Pubitemid 38128616)
17. Inoue H and Tanabe T: Transcriptional role of the nuclear factor kappa B site in the induction by lipopolysaccharide and suppression by dexamethasone of cyclooxygenase-2 in U937 cells. Biochem Biophys Res Commun 244: 143-148, 1998. (Pubitemid 28419914)
18. Inoue H, Yokoyama C, Hara S, Tone Y and Tanabe T: Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. J Biol Chem 270: 24965-24971, 1995.
19. Inoue H, Nanayama T, Hara S, Yokoyama C and Tanabe T: The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells. FEBS Lett 350: 51-54, 1994.
20. Hou D-X, Fukuda M, Fujii M and Fuke Y: Transcriptional regulation of nicotinamide adenine dinucleotide phosphate: quinone oxidoreductase in murine hepatoma cells by 6-(methylsufinyl)hexyl isothiocyanate, an active principle of wasabi (Eutrema wasabi Maxim). Cancer Lett 20: 195-200, 2000.
21. Duque J, Díaz-Muñoz MD, Fresno M and Iñiguez MA: Upregulation of cyclooxygenase-2 by interleukin-1beta in colon carcinoma cells. Cell Signal 18: 1262-1269, 2006. (Pubitemid 44275220)
22. Moore PE, Lahiri T, Laporte JD, Church T, Panettieri RA and Shore SA: Selected contribution: synergism between TNF-alpha and IL-1 beta in airway smooth muscle cells: implications for beta-adrenergic responsiveness. J Appl Physiol 91: 1467-1474, 2001. (Pubitemid 32803947)
23. Lin CC, Hsiao LD, Chien CS, Lee CW, Hsieh JT and Yang CM: Tumor necrosis factor-alpha-induced cyclooxygenase-2 expression in human tracheal smooth muscle cells: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB. Cell Signal 16: 597-607, 2004.
24. Pettus BJ, Bielawski J, Porcelli AM, Reames DL, Johnson KR, Morrow J, Chalfant CE, Obeid LM and Hannun YA: The sphingosine kinase 1/sphingosine-1- phosphate pathway mediates COX-2 induction and PGE2 production in response to TNF-alpha. FASEB J 17: 1411-1421, 2003. (Pubitemid 36939148)
25. Uto T, Fujii M and Hou D-X: Inhibition of lipopolysaccharide-induced cyclooxygenase-2 transcription by 6-(methylsulfinyl)hexyl isothiocyanate, a chemopreventive compound from Wasabia japonica (Miq.) Matsumura, in mouse macrophages. Biochem Pharmacol 70: 1772-1784, 2005. (Pubitemid 41612008)
26. Thomas B, Berenbaum F, Humbert L, Bian H, Bereziat G, Crofford L and Olivier JL: Critical role of C/EBPdelta and C/EBPbeta factors in the stimulation of the cyclooxygenase-2 gene transcription by interleukin-1beta in articular chondrocytes. Eur J Biochem 267: 6798-6809, 2000.
27. D'Acquisto F, Iuvone T, Rombola L, Sautebin L, Di Rosa M and Carnuccio R: Involvement of NF-kappaB in the regulation of cyclooxygenase-2 protein expression in LPS-stimulated J774 macrophages. FEBS Lett 418: 175-178, 1997. (Pubitemid 27514441)
28. Zandi E, Rothwarf DM, Delhase M, Hayakawa M and Karin M: The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation. Cell 91: 243-252, 1997. (Pubitemid 27456391)
29. Mestre JR, Mackrell PJ, Rivadeneira DE, Stapleton PP, Tanabe T and Daly JM: Redundancy in the signaling pathways and promoter elements regulating cyclooxygenase-2 gene expression in endotoxin-treated macrophage/monocytic cells. J Biol Chem 276: 3977-3982, 2001.
30. Boehm U, Klamp T, Groot M and Howard JC: Cellular responses to interferon-gamma. Annu Rev Immunol 15: 749-795, 1997.
31. Blanco JC, Contursi C, Salkowski CA, De Witt DL, Ozato K and Vogel SN: Interferon regulatory factor (IRF)-1 and IRF-2 regulate interferon gamma-dependent cyclooxygenase 2 expression. J Exp Med 191: 2131-2144, 2000. (Pubitemid 30416360)
32. Chen CC, Wang JK and Chen WC: TPA induces translocation but not down-regulation of new PKC isoform eta in macrophages, MDCK cells and astrocytes. FEBS Lett 412: 30-34, 1997.
33. Chang MS, Chen BC, Yu MT, Sheu JR, Chen TF and Lin CH: Phorbol 12-myristate 13-acetate upregulates cyclooxygenase-2 expression in human pulmonary epithelial cells via Ras, Raf-1, ERK, and NF-kappaB, but not p38 MAPK, pathways. Cell Signal 17: 299-310, 2005. (Pubitemid 39574691)
34. Subbaramaiah K, Cole PA and Dannenberg AJ: Retinoids and carnosol suppress cyclooxygenase-2 transcription by CREB-binding protein/p300-dependent and -independent mechanisms. Cancer Res 62: 2522-2530, 2002. (Pubitemid 34462729)