Identification of c-Yes expression in the nuclei of hepatocellular carcinoma cells: Involvement in the early stages of hepatocarcinogenesis

International Journal of Oncology

Volumn 30, Issue 1, 2007, Pages 105-111

  Nonomura, Takako ^a   Masaki, Tsutomu ^a   Morishita, Asahiro ^a   Jian, Gong ^a   Uchida, Naohito ^a   Himoto, Takashi ^a   Izuishi, Kunihiko ^a   Iwama, Hisakazu ^a   Yoshiji, Hitoshi ^b   Watanabe, Seishiro ^a   Kurokohchi, Kazutaka ^a   Kuriyama, Shigeki ^a  

^a KAGAWA UNIVERSITY   (Japan)

^b NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

c Yes; Cyclin dependent kinase 1; Hepatocellular carcinoma; Oncogene; Tyrosine kinase

Indexed keywords

CANCER ANTIBODY; PROTEIN KINASE YES; YES1 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CANCER STAGING; CELL NUCLEUS; DNA MICROARRAY; FEMALE; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; LIVER TUMOR; MALE; MIDDLE AGED; PATHOLOGY; TUMOR CELL LINE;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, NEOPLASM; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL NUCLEUS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTO-ONCOGENE PROTEINS C-YES;

EID: 39049182469     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.30.1.105     Document Type: Article

References (27)

1. c-src kinase by middle T antigen binding or by dephosphorylation. EMBO J 4: 1471-1477, 1985.
2. c-src. Cell 49: 75-82, 1987.
3. c-src mutated in the carboxy-terminal regulatory domain. Cell 49: 83-91, 1987.
4. Bolen JB: Non-receptor tyrosine protein kinases. Oncogene 8: 2025-2031, 1993.
5. Park J, Meisler AI and Cartwright CA: c-Yes tyrosine kinase activity in human colon carcinoma. Oncogene 8: 2627-2635, 1993.
6. Hirsch CL, Smith-Windsor EL and Bonham K: Src family kinase members have a common response to histone deacetylase inhibitors in human colon cancer cells. Int J Cancer 118: 547-554, 2006.
7. Loganzo F Jr, Dosik JS, Zhao Y, Vidal MJ, Nanus DM, Sudol M and Albino AP: Elevated expression of protein tyrosine kinase c-Yes, but not c-Src, in human malignant melanoma. Oncogene 8: 2637-2644, 1993.
8. Marchetti D, Parikh N, Sudol M and Gallick GE: Stimulation of the protein tyrosine kinase c-Yes but not c-Src by neurotrophins in human brain-metastatic melanoma cells. Oncogene 16: 3253-3260, 1998.
9. Feng H, Masaki T, Nonomura T, Morishita A, Jian G, Nakai S, Deguchi A, Uchida N, Himoto T, Iwama H, Usuki H, Wakabayashi H, Izuishi K, Yoshiji H, Kurokohchi K and Kuriyama S: Activation of c-Yes in hepatocellular carcinoma: a preliminary study. World J Gastroenterol (In press).
10. c-yes in human colorectal carcinoma liver metastases. Clin Cancer Res 2: 1397-1404, 1996.
11. International Working Party: Terminology of nodular hepatocellular lesions. Hepatology 22: 983-993, 1995.
12. International Union Against Cancer (UICC): TNM Classification of Malignant Tumors. 5th edition. Sobin LH and Wittekind Ch (eds). Wiley-Liss, New York, pp74-77, 1977.
13. Desmet VJ, Gerber M, Hoofnagle JH, Manns M and Scheuer PJ: Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 19: 1513-1520, 1994.
14. Yoshida S, Masaki T, Feng H, Yuji J, Miyauchi Y, Funaki T, Yoshiji H, Matsumoto K, Uchida N, Watanabe S, Kurokohchi K and Kuriyama S: Enhanced expression of adaptor molecule p46 Shc in nuclei of hepatocellular carcinoma cells: study of LEC rats. Int J Oncol 25: 1089-1096, 2004.
15. Masaki T, Tokuda M, Yoshida S, Nakai S, Morishita A, Uchida N, Funaki T, Kita Y, Funakoshi F, Nonomura T, Himoto T, Deguchi A, Kimura Y, Izuishi K, Wakabayashi H, Usuki H, Yoshiji H, Watanabe S, Kurokohchi K and Kuriyama S: Comparison study of the expressions of myristoylated alanine-rich C kinase substrate in hepatocellular carcinoma, liver cirrhosis, chronic hepatitis and normal liver. Int J Oncol 26: 661-671, 2005.
16. Yukimasa S, Masaki T, Yoshida S, Uchida N, Watanabe S, Usuki H, Yoshiji H, Maeta T, Ebara K, Nakatsu T, Kurokohchi K and Kuriyama S: Enhanced expression of p46 Shc in the nucleus and p52 Shc in the cytoplasm of human gastric cancer. Int J Oncol 26: 905-911, 2005.
17. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
18. Towbin H, Staehelin T and Gordon J: Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76: 4350-4354, 1979.
19. Masaki T, Tokuda M, Shiratori Y, Shirai M, Matsumoto K, Nishioka M and Omata M: A possible novel src-related tyrosine kinase in cancer cells of LEC rats that develop hepatocellular carcinoma. J Hepatol 32: 92-99, 2000.
20. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
21. cdc2. Cancer Res 56: 3617-3621, 1996.
22. Radha V, Nambirajan S and Swarup G: Association of Lyn tyrosine kinase with the nuclear matrix and cell-cycle-dependent changes in matrix-associated tyrosine kinase activity. Eur J Biochem 236: 352-359, 1996.
23. Zhao Y, Sudol M, Hanafusa H and Krueger J: Increased tyrosine kinase activity of c-Src during calcium-induced keratinocyte differentiation. Proc Natl Acad Sci USA 89: 8298-8302, 1992.
24. Kamei T, Hamlin GP, Chapman BM, Burkhardt AL, Bolen JB and Soares MJ: Signaling pathways controlling trophoblast cell differentiation: Src family protein tyrosine kinases in the rat. Biol Reprod 57: 1302-1311, 1997.
25. Zhao Y, Uyttendaele H, Krueger JG, Sudol M and Hanafusa H: Inactivation of c-Yes tyrosine kinase by elevation of intracellular calcium levels. Mol Cell Biol 12: 7507-7514, 1993.
26. Park J, Meisler AI and Cartwright CA: c-Yes tyrosine kinase activity in human colon carcinoma. Oncogene 8: 2627-2635, 1993.
27. c-yes in normal, hyperplastic and neoplastic human epidermis. Oncogene 6: 933-940, 1991.