메뉴 건너뛰기




Volumn 72, Issue 5-6, 2008, Pages 314-321

The role of adjuvant chemotherapy for patients with resected pancreatic cancer: Systematic review of randomized controlled trials and meta-analysis

Author keywords

Adjuvant chemotherapy; Chemoradiation; Meta analysis; Pancreatic cancer

Indexed keywords

CISPLATIN; DOXORUBICIN; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; MITOMYCIN C;

EID: 39049173392     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000113054     Document Type: Article
Times cited : (76)

References (30)
  • 1
    • 34547132141 scopus 로고    scopus 로고
    • Clinical cancer advances 2006: Major research advances in cancer treatment, prevention, and screening - a report from the American Society of Clinical Oncology
    • Ozols RF, Herbst RS, Colson YL, et al: Clinical cancer advances 2006: major research advances in cancer treatment, prevention, and screening - a report from the American Society of Clinical Oncology. J Clin Oncol 2007;25:146-162.
    • (2007) J Clin Oncol , vol.25 , pp. 146-162
    • Ozols, R.F.1    Herbst, R.S.2    Colson, Y.L.3
  • 2
    • 0141888993 scopus 로고    scopus 로고
    • Treatment of pancreatic cancer: Challenge of the facts
    • Beger HG, Rau B, Gansauge F, et al: Treatment of pancreatic cancer: challenge of the facts. World J Surg 2003;27:1075-1084.
    • (2003) World J Surg , vol.27 , pp. 1075-1084
    • Beger, H.G.1    Rau, B.2    Gansauge, F.3
  • 3
    • 33645527163 scopus 로고    scopus 로고
    • Survival among patients with adenocarcinoma of the pancreas: A population-based study (United States)
    • Cress RD, Yin D, Clarke L, et al: Survival among patients with adenocarcinoma of the pancreas: a population-based study (United States). Cancer Causes Control 2006;17:403-409.
    • (2006) Cancer Causes Control , vol.17 , pp. 403-409
    • Cress, R.D.1    Yin, D.2    Clarke, L.3
  • 4
    • 8744252191 scopus 로고    scopus 로고
    • Current standards of surgery for pancreatic cancer
    • Alexakis N, Halloran C, Raraty M, et al: Current standards of surgery for pancreatic cancer. Br J Surg 2004;91:1410-1427.
    • (2004) Br J Surg , vol.91 , pp. 1410-1427
    • Alexakis, N.1    Halloran, C.2    Raraty, M.3
  • 5
    • 0035155586 scopus 로고    scopus 로고
    • Results of total pancreatectomy for adenocarcinoma of the pancreas
    • Karpoff HM, Klimstra DS, Brennan MF, et al: Results of total pancreatectomy for adenocarcinoma of the pancreas. Arch Surg 2001;136:44-47.
    • (2001) Arch Surg , vol.136 , pp. 44-47
    • Karpoff, H.M.1    Klimstra, D.S.2    Brennan, M.F.3
  • 6
    • 0031717968 scopus 로고    scopus 로고
    • The retroperitoneal resection margin and vessel involvement are important factors determining survival after pancreaticoduodenectomy for ductal adenocarcinoma of the head of the pancreas
    • Lüttges J, Vogel I, Menke M, et al: The retroperitoneal resection margin and vessel involvement are important factors determining survival after pancreaticoduodenectomy for ductal adenocarcinoma of the head of the pancreas. Virchow Arch 1998;433:237-242.
    • (1998) Virchow Arch , vol.433 , pp. 237-242
    • Lüttges, J.1    Vogel, I.2    Menke, M.3
  • 7
    • 33846405332 scopus 로고    scopus 로고
    • Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer
    • Oettle H, Post S, Neuhaus P, et al: Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer. JAMA 2007;297:267-277.
    • (2007) JAMA , vol.297 , pp. 267-277
    • Oettle, H.1    Post, S.2    Neuhaus, P.3
  • 8
    • 0017365573 scopus 로고
    • Design and analysis of randomized clinical trials requiring prolonged observation of each patient: Analysis and examples (II)
    • Peto R, Pike MC, Armitage P, et al: Design and analysis of randomized clinical trials requiring prolonged observation of each patient: analysis and examples (II). Br J Cancer 1977;35:1-39.
    • (1977) Br J Cancer , vol.35 , pp. 1-39
    • Peto, R.1    Pike, M.C.2    Armitage, P.3
  • 10
    • 0027461223 scopus 로고
    • Adjuvant combination chemotherapy (AMF) following radical resection of carcinoma of the pancreas and papilla of vater - results of a controlled, prospective, randomised multicentre study
    • Bakkevold KE, Arnesjø B, Dahl O, et al: Adjuvant combination chemotherapy (AMF) following radical resection of carcinoma of the pancreas and papilla of vater - results of a controlled, prospective, randomised multicentre study. Eur J Cancer 1993;29:698-703.
    • (1993) Eur J Cancer , vol.29 , pp. 698-703
    • Bakkevold, K.E.1    Arnesjø, B.2    Dahl, O.3
  • 11
    • 33645858256 scopus 로고    scopus 로고
    • A multicenter randomized controlled trial to evaluate the effect of adjuvant cisplatin and 5-fluorouracil therapy after curative resection in cases of pancreatic cancer
    • Kosuge T, Kiuchi T, Mukai K, et al: A multicenter randomized controlled trial to evaluate the effect of adjuvant cisplatin and 5-fluorouracil therapy after curative resection in cases of pancreatic cancer. Jpn J Clin Oncol 2006;36:159-165.
    • (2006) Jpn J Clin Oncol , vol.36 , pp. 159-165
    • Kosuge, T.1    Kiuchi, T.2    Mukai, K.3
  • 12
    • 0037108106 scopus 로고    scopus 로고
    • Is post-operative adjuvant chemotherapy useful for gallbladder carcinoma? A phase III multicenter prospective randomized controlled trial in patients with resected pancreaticobiliary carcinoma
    • Takada T, Amano H, Yasuda H, et al: Is post-operative adjuvant chemotherapy useful for gallbladder carcinoma? A phase III multicenter prospective randomized controlled trial in patients with resected pancreaticobiliary carcinoma. Cancer 2002;95:1685-1695.
    • (2002) Cancer , vol.95 , pp. 1685-1695
    • Takada, T.1    Amano, H.2    Yasuda, H.3
  • 13
    • 0035841631 scopus 로고    scopus 로고
    • Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer: A randomized controlled trial
    • Neoptolemos JP, Dunn JA, Stocken DD, et al: Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer: a randomized controlled trial. Lancet 2001;358:1576-1585.
    • (2001) Lancet , vol.358 , pp. 1576-1585
    • Neoptolemos, J.P.1    Dunn, J.A.2    Stocken, D.D.3
  • 14
    • 12144287320 scopus 로고    scopus 로고
    • A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer
    • Neoptolemos JP, Stocken DD, Friess H, et al: A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N Engl J Med 2004;350:1200-1210.
    • (2004) N Engl J Med , vol.350 , pp. 1200-1210
    • Neoptolemos, J.P.1    Stocken, D.D.2    Friess, H.3
  • 15
    • 21044451123 scopus 로고    scopus 로고
    • Meta-analysis of randomized adjuvant therapy trials for pancreatic cancer
    • Stocken DD, Büchler MW, Dervenis C, et al: Meta-analysis of randomized adjuvant therapy trials for pancreatic cancer. Br J Cancer 2005;92:1372-1381.
    • (2005) Br J Cancer , vol.92 , pp. 1372-1381
    • Stocken, D.D.1    Büchler, M.W.2    Dervenis, C.3
  • 16
    • 33646687064 scopus 로고    scopus 로고
    • Is adjuvant 5-FU-based chemoradiotherapy for resectable pancreatic adenocarcinoma beneficial? A meta-analysis of an unanswered question
    • Khanna A, Walker GR, Livingstone AS, et al: Is adjuvant 5-FU-based chemoradiotherapy for resectable pancreatic adenocarcinoma beneficial? A meta-analysis of an unanswered question. J Gastrointest Surg 2006;10:689-697.
    • (2006) J Gastrointest Surg , vol.10 , pp. 689-697
    • Khanna, A.1    Walker, G.R.2    Livingstone, A.S.3
  • 17
    • 33747166432 scopus 로고    scopus 로고
    • Consensus report of the International Society of Gastrointestinal Oncology on therapeutic progress in advanced pancreatic cancer
    • Hochster HS, Haller DG, De Gramont A, et al: Consensus report of the International Society of Gastrointestinal Oncology on therapeutic progress in advanced pancreatic cancer. Cancer 2006;107:676-685.
    • (2006) Cancer , vol.107 , pp. 676-685
    • Hochster, H.S.1    Haller, D.G.2    De Gramont, A.3
  • 18
    • 0021867923 scopus 로고
    • Pancreatic cancer. Adjuvant combined radiation and chemotherapy following curative resection
    • Kalser MH, Ellenberg SS: Pancreatic cancer. Adjuvant combined radiation and chemotherapy following curative resection. Arch Surg 1985;120:899-903.
    • (1985) Arch Surg , vol.120 , pp. 899-903
    • Kalser, M.H.1    Ellenberg, S.S.2
  • 19
    • 0023262033 scopus 로고
    • Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer
    • Gastrointestinal Tumour Study Group
    • Gastrointestinal Tumour Study Group: Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Cancer 1987;59:2006-2010.
    • (1987) Cancer , vol.59 , pp. 2006-2010
  • 20
    • 0033497862 scopus 로고    scopus 로고
    • Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: Phase III trial of the EORTC gastrointestinal tract cancer cooperative group
    • Klinkenbijl JH, Jeekel J, Sahmoud T, et al: Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: phase III trial of the EORTC gastrointestinal tract cancer cooperative group. Ann Surg 1999;230:776-784.
    • (1999) Ann Surg , vol.230 , pp. 776-784
    • Klinkenbijl, J.H.1    Jeekel, J.2    Sahmoud, T.3
  • 21
    • 39049102227 scopus 로고    scopus 로고
    • RTOG 9704 a phase III study of adjuvant pre and post chemoradiation (CRT) 5-FU vs. gemcitabine (G) for resected pancreatic adenocarcinoma (abstract 4007)
    • 180s
    • Regine WF, Winter KW, Abrams R, et al: RTOG 9704 a phase III study of adjuvant pre and post chemoradiation (CRT) 5-FU vs. gemcitabine (G) for resected pancreatic adenocarcinoma (abstract 4007). J Clin Oncol 2006;24:180s.
    • (2006) J Clin Oncol , vol.24
    • Regine, W.F.1    Winter, K.W.2    Abrams, R.3
  • 22
    • 33746905054 scopus 로고    scopus 로고
    • Adjuvant gemcitabine and concurrent radiation for patients with resected pancreatic cancer: A phase II study
    • Blackstock AW, Mornex F, Partensky C, et al: Adjuvant gemcitabine and concurrent radiation for patients with resected pancreatic cancer: a phase II study. Br J Cancer 2006;95:260-265.
    • (2006) Br J Cancer , vol.95 , pp. 260-265
    • Blackstock, A.W.1    Mornex, F.2    Partensky, C.3
  • 23
    • 1242338157 scopus 로고    scopus 로고
    • Concurrent chemoradiotherapy with gemcitabine and cisplatin after incomplete (R1) resection of locally advanced pancreatic cancer
    • Wilkowski R, Thoma M, Duhmke E, et al: Concurrent chemoradiotherapy with gemcitabine and cisplatin after incomplete (R1) resection of locally advanced pancreatic cancer. Int J Radiat Oncol Biol Phys 2004;58:768-772.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 768-772
    • Wilkowski, R.1    Thoma, M.2    Duhmke, E.3
  • 24
    • 26944460867 scopus 로고    scopus 로고
    • Phase III trial of postoperative cisplatin, interferon α-2b, and 5-FU combined with external radiation treatment versus 5-FU alone for patients with resected pancreatic adenocarcinoma - CapRI: Study protocol
    • Knaebel HP, Märten A, Schmidt J, et al: Phase III trial of postoperative cisplatin, interferon α-2b, and 5-FU combined with external radiation treatment versus 5-FU alone for patients with resected pancreatic adenocarcinoma - CapRI: study protocol. BMC Cancer 2005;5:37-44.
    • (2005) BMC Cancer , vol.5 , pp. 37-44
    • Knaebel, H.P.1    Märten, A.2    Schmidt, J.3
  • 25
    • 33644968548 scopus 로고    scopus 로고
    • Phase I trial evaluating the safety of bevacizumab with concurrent radiotherapy and capecitabine in locally advanced pancreatic cancer
    • Crane CH, Ellis LM, Abbruzzese JL, et al: Phase I trial evaluating the safety of bevacizumab with concurrent radiotherapy and capecitabine in locally advanced pancreatic cancer. J Clin Oncol 2006;24:1145-1151.
    • (2006) J Clin Oncol , vol.24 , pp. 1145-1151
    • Crane, C.H.1    Ellis, L.M.2    Abbruzzese, J.L.3
  • 26
    • 33750552959 scopus 로고    scopus 로고
    • Prognostic and therapeutic significance of carbohydrate antigen 19-9 as tumor marker in patients with pancreatic cancer
    • Boeck S, Stieber P, Holdenrieder S, et al: Prognostic and therapeutic significance of carbohydrate antigen 19-9 as tumor marker in patients with pancreatic cancer. Oncology 2006;70:255-264.
    • (2006) Oncology , vol.70 , pp. 255-264
    • Boeck, S.1    Stieber, P.2    Holdenrieder, S.3
  • 27
    • 33745552215 scopus 로고    scopus 로고
    • Perioperative CA 19-9 levels can predict stage and survival in patients with resectable pancreatic adenocarcinoma
    • Ferrone CR, Finkelstein DM, Thayer SP, et al: Perioperative CA 19-9 levels can predict stage and survival in patients with resectable pancreatic adenocarcinoma. J Clin Oncol 2006;24:2897-2902.
    • (2006) J Clin Oncol , vol.24 , pp. 2897-2902
    • Ferrone, C.R.1    Finkelstein, D.M.2    Thayer, S.P.3
  • 28
    • 39049113630 scopus 로고    scopus 로고
    • Post-resection CA 19-9 predicts overall survival (OS) in patients treated with adjuvant chemoradiation: A secondary endpoint of RTOG 9704 (abstract 4522)
    • 203s
    • Berger AC, Winter K, Hoffmann J, et al: Post-resection CA 19-9 predicts overall survival (OS) in patients treated with adjuvant chemoradiation: A secondary endpoint of RTOG 9704 (abstract 4522). J Clin Oncol 2007;25:203s.
    • (2007) J Clin Oncol , vol.25
    • Berger, A.C.1    Winter, K.2    Hoffmann, J.3
  • 29
    • 0035212974 scopus 로고    scopus 로고
    • Influence of resection margins on survival for patients with pancreatic cancer treated with adjuvant chemoradiation and/or chemotherapy in the ESPAC-1 randomized controlled trial
    • Neoptolemos JP, Stocken DD, Dunn JA, et al: Influence of resection margins on survival for patients with pancreatic cancer treated with adjuvant chemoradiation and/or chemotherapy in the ESPAC-1 randomized controlled trial. Ann Surg 2001;234:758-768.
    • (2001) Ann Surg , vol.234 , pp. 758-768
    • Neoptolemos, J.P.1    Stocken, D.D.2    Dunn, J.A.3
  • 30
    • 33749609699 scopus 로고    scopus 로고
    • Redefining the R1 resection in pancreatic cancer
    • Verbeke CS, Leitch D, Menon KV, et al: Redefining the R1 resection in pancreatic cancer. Br J Surg 2006;93:1232-1237.
    • (2006) Br J Surg , vol.93 , pp. 1232-1237
    • Verbeke, C.S.1    Leitch, D.2    Menon, K.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.