FGF-2-induced functional improvement from neonatal motor cortex injury via corticospinal projections

Experimental Brain Research

Volumn 185, Issue 3, 2008, Pages 453-460

  Monfils, Marie H ^a,c   Driscoll, Ira ^a   Vavrek, Romana ^b   Kolb, Bryan ^a   Fouad, Karim ^b  

^a UNIVERSITY OF LETHBRIDGE   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c NEW YORK UNIVERSITY   (United States)

Author keywords

Corticospinal; EMG; FGF 2; Motor cortex; Reaching; Recovery of function

Indexed keywords

FIBROBLAST GROWTH FACTOR 2;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARM MUSCLE; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN INJURY; BRAIN REGION; CHEMICAL LABELING; CONTROLLED STUDY; CONVALESCENCE; DRUG EFFECT; ELECTROMYOGRAPHY; EVOKED MUSCLE RESPONSE; EXTENSOR MUSCLE; MALE; MOTOR CORTEX; MOTOR PERFORMANCE; NERVE CELL NETWORK; NERVE PROJECTION; NEUROANATOMY; NEUROPHYSIOLOGY; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PYRAMIDAL TRACT; RAT; TREATMENT OUTCOME; WRIST;

ANIMALS; ANIMALS, NEWBORN; BRAIN INJURIES; FIBROBLAST GROWTH FACTOR 2; MALE; MOTOR CORTEX; PYRAMIDAL TRACTS; RATS; RATS, LONG-EVANS; RECOVERY OF FUNCTION;

EID: 39049172846     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-007-1172-0     Document Type: Article

References (25)

1. Fouad K, Pedersen V, Schwab ME, Brosamle C (2001) Cervical sprouting of corticospinal fibers after thoracic spinal cord injury accompanies shifts in evoked motor responses. Curr Biol 11(22):1766-1770
2. Ganat Y, Soni S, Chacon M, Schwartz ML, Vaccarino FM (2002) Chronic hypoxia up-regulates fibroblast growth factor ligands in the perinatal brain and induces fibroblast growth factor-responsive radial glial cells in the sub-ependymal zone. Neuroscience 112(4):977-991
3. Kolb B (1987) Recovery from early cortical damage in rats. I. Differential behavioral and anatomical effects of frontal lesions at different ages of neural maturation. Behav Brain Res 25(3):205-20
4. Kolb B, Gibb R, Gorny G, Whishaw IQ (1998) Possible regeneration of rat medial frontal cortex following neonatal frontal lesions. Behav Brain Res 91(1-2):127-141
5. Kolb B, Cioe J, Whishaw IQ (2000) Is there an optimal age for recovery from motor cortex lesions? I. Behavioural and anatomical sequelae of bilateral motor cortex lesions in rats on postnatal days 1, 10, and in adulthood. Brain Res 882:62-74
6. Kuhn HG, Winkler J, Kempermann G, Thal LJ, Gage FH (1997) Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain. J Neurosci 17(15):5820-5829
7. Li B, DiCicco-Bloom E (2004) Basic fibroblast growth factor exhibits dual and rapid regulation of cyclin D1 and p27 to stimulate proliferation of rat cerebral cortical precursors. Dev Neurosci 26(2-4):197-207
8. Liesi P, Kirkwood T, Vaheri A (1986) Fibronectin is expressed by astrocytes cultured from embryonic and early postnatal rat brain. Exp Cell Res 163(1):175-185
9. Mahler M, Ben-Ari Y, Represa A (1997) Differential expression of fibronectin, tenascin-C and NCAMs in cultured hippocampal astrocytes activated by kainate, bacterial lipopolysaccharide or basic fibroblast growth factor. Brain Res 775(1-2):63-73
10. Matsushima K, Schmidt-Kastner R, Hogan MJ, Hakim AM (1998) Cortical spreading depression activates trophic factor expression in neurons and astrocytes and protects against subsequent focal brain ischemia. Brain Res 807(1-2):47-60
11. Matthiessen HP, Schmalenbach C, Muller HW (1989) Astroglia-released neurite growth-inducing activity for embryonic hippocampal neurons is associated with laminin bound in a sulfated complex and free fibronectin. Glia 2(3):177-178
12. McFarlane S, McNeill L, Holt CE (1995) FGF signaling and target recognition in the developing Xenopus visual system. Neuron 15(5):1017-1028
13. Monfils MH, Driscoll I, Vandenberg PM, Thomas NJ, Danka D, Kleim JA, Kolb B (2005) Basic fibroblast growth factor stimulates functional recovery after neonatal lesions of motor cortex in rats. Neuroscience 134:1-8
14. Monfils MH, Driscoll I, Melvin NR, Kolb B (2006a) Developmental expression of FGF-2 in the rat brain. Neuroscience 141(1):213-221
15. Monfils MH, Driscoll I, Kamitakahara H, Wilson B, Flynn C, Teskey GC, Kleim JA, Kolb B (2006b) FGF-2-induced cell proliferation stimulates anatomical, neurophysiological, and functional recovery from neonatal motor cortex injury. Eur J Neurosci 24(3):739-749
16. Paxinos G, Watson C (1985) The rat brain in stereotaxic coordinates. Academic, New York
17. Raballo R, Rhee J, Lyn-Cook R, Leckman JF, Schwartz ML, Vaccarino FM (2000) Basic fibroblast growth factor (Fgf2) is necessary for cell proliferation and neurogenesis in the developing cerebral cortex. J Neurosci 20(13):5012-5023
18. Raineteau O, Schwab ME (2001) Plasticity of motor systems after incomplete spinal cord injury. Nat Rev Neurosci 2(4):263-273 (Review)
19. Ramirez JJ, Finklestein SP, Keller J, Abrams W, George MN, Parakh T (1999) Basic fibroblast growth factor enhances axonal sprouting after cortical injury in rats. Neuroreport 10(6):1201-1204
20. Rowntree S, Kolb B (1997) Blockade of basic fibroblast growth factor retards recovery from motor cortex injury in rats. Eur J Neurosci 9(11):2432-2441
21. Smith LK, Metz GA (2005) Dietary restriction alters fine motor function in rats. Physiol Behav 85(5):581-592
22. Tao Y, Black IB, DiCicco-Bloom E (1996) Neurogenesis in neonatal rat brain is regulated by peripheral injection of basic fibroblast growth factor (bFGF). J Comp Neurol 376(4):653-663
23. Wagner JP, Black IB, DiCicco-Bloom E (1999) Stimulation of neonatal and adult brain neurogenesis by subcutaneous injection of basic fibroblast growth factor. J Neurosci 19(14):6006-6016
24. Whishaw IQ, Pellis SM, Gorny BP, Pellis VC (1991) The impairments in reaching and the movements of compensation in rats with motor cortex lesions: an endpoint, videorecording, and movement notation analysis. Behav Brain Res 42(1):77-91
25. Z'Graggen WJ, Metz GA, Kartje GL, Thallmair M, Schwab ME (1998) Functional recovery and enhanced corticofugal plasticity after unilateral pyramidal tract lesion and blockade of myelin-associated neurite growth inhibitors in adult rats. J Neurosci 18(12):4744-4757