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Guarantor of the article: Y. R. Wang, M.D., Ph.D. Specific author contributions: conception and design: Y. R. Wang, Robert S. Fisher, and Henry P. Parkman; acquisition of data and data analysis: Y. R. Wang; interpretation of results: Y. R. Wang, Robert S. Fisher, and Henry P. Parkman; drafting of manuscript: Y. R. Wang; and critical revision of manuscript: Y. R. Wang, Robert S. Fisher, and Henry P. Parkman. Financial support: This study was supported in part by a NIH Midcareer Investigator Award in Patient-Oriented Research to HP Parkman (NIH DK02921). Potential competing interests: None.
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