Prevalence, detection and treatment of delirium in terminal cancer inpatients: A prospective survey

Japanese Journal of Clinical Oncology

Volumn 38, Issue 1, 2008, Pages 56-63

  Fang, Chun Kai ^a   Chen, Hong Wen ^a   Liu, Shen Ing ^a   Lin, Chen Ju ^a   Tsai, Li Yun ^a   Lai, Yuen Liang ^a,b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b MACKAY MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Delirium; Detection; Prevalence; Terminal cancer inpatient; Treatment

Indexed keywords

HALOPERIDOL; NEUROLEPTIC AGENT; OLANZAPINE; OPIATE; QUETIAPINE; SEDATIVE AGENT;

ADULT; AGED; ANTICHOLINERGIC EFFECT; ARTICLE; CANCER PALLIATIVE THERAPY; CANCER PATIENT; CLINICAL EVALUATION; CONFIDENCE INTERVAL; CONTROLLED STUDY; DELIRIUM; DISEASE CLASSIFICATION; EXTRAPYRAMIDAL SYNDROME; FEMALE; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MORTALITY; PRESCRIPTION; PREVALENCE; PROSPECTIVE STUDY; PSYCHIATRIC DIAGNOSIS; PSYCHIATRIST; RATING SCALE; SCREENING; SIDE EFFECT; TAIWAN; TERMINAL DISEASE;

ADULT; AGED; AGED, 80 AND OVER; CRITICAL ILLNESS; DELIRIUM; DIAGNOSIS, DIFFERENTIAL; FEMALE; HEALTH SURVEYS; HOSPICE CARE; HUMANS; INPATIENTS; MALE; MIDDLE AGED; NEOPLASMS; PALLIATIVE CARE; PREVALENCE; PROSPECTIVE STUDIES; SURVIVAL RATE; TAIWAN;

EID: 39049112462     PISSN: 03682811     EISSN: 14653621     Source Type: Journal    
DOI: 10.1093/jjco/hym155     Document Type: Article

References (56)

1. Centeno C, Sanz A, Bruera E. Delirium in advanced cancer patients. Palliat Med 2004;18:184-94.
2. Casarett DJ, Inouye SK. Diagnosis and management of delirium near the end of life. Ann Intern Med 2001;135:32-40.
3. Grassi L, Gritti P, Rigatelli M, Gala C. Psychosocial problems secondary to cancer: An Italian multicentre survey of consultation-liaison psychiatry in oncology. Eur J Cancer 2000;36:579-85.
4. Massie MJ, Holland JC. Consultation and liaison issues in cancer care. Psychiatr Med 1987;5:343-59.
5. Akechi T, Nakano T, Okamura H, Ueda S, Akizuki N, Nakanishi T, et al. Psychiatric disorders in cancer patients: Descriptive analysis of 1721 psychiatric referrals at two Japanese cancer center hospitals. Jpn J Clin Oncol 2001;31:188-194.
6. Trzepacz PT, Breitbart W. Practice guideline for the treatment of patients with delirium. Am J Psychiatry 1999; 156(Suppl 5):1-20.
7. Massie MJ, Holland J, Glass E. Delirium in terminally cancer patients. Am J Psychiatry 1983,140:1048-50.
8. Minagawa H, Uchitomi Y, Yamawaki S, Ishitani K, Psychiatric morbidity in terminally ill cancer patients. A prospective study. Cancer 1996;78:1131-7.
9. Michaud L, Burnand B, Stiefel F. Taking care of the terminally, ill cancer patient: Delirium as a symptom of terminal disease. Ann Oncol 2004;15(Suppl 4):iV199-203.
10. Loge JH, Bjermstad MJ, Kassa S. Delirium in palliative care. (in Norwegian) Tidsskr Nor Laegeforen 2006;126:616-9.
11. Lawlor PG, Gagnon P, Mancini IL, Pereira JL, Hanson J, Suarez-Almazor ME, et al. Occurrence, causes, and outcome of delirium in patients with advanced cancer - a prospective study. Arch Intern Med 2000;160:786-94.
12. Gagnon P, Allard P, Masse B, DeSerres M. Delirium in terminal cancer: A prospective study using daily screening, early diagnosis, and continuous monitoring. J Pain Symptom Manage 2000;19:412-26.
13. Akechi T, Nakano T, Uchitomi Y. Scientific background of psycho-oncology (in Japanese). Seishin Shinkeigaku Zasshi 2004;106:764-71.
14. Voyer P, McCusker J, Cole MG, Khomenko L. Influence of prior cognitive impairment on severity of delirium symptoms among old patients. J Neurosci Nurs 2006;38:90-101.
15. Anthony JC, LeResche LA, Von Korff MR, Niaz U, Folstein MF. Screening for delirium on a general medical ward: The tachistoscope and a global accessibility rating. Gen Hosp Psychiatry 1985;7:36-42.
16. McNicoll L, Pisani MA, Ely EW, Gifford D, Inouye SK. Detection of delirium in the intensive care unit: Comparison of confusion assessment method for intensive care unit with confusion assessment method rating. J Am Geriatr Soc 2005;53:495-500.
17. Pisani MA, Araujo KL, Van Ness PH, Zharg Y, Ely EW, Inouye SK. A research algorithm to improve detection of delirium in the intensive care unit. Crit Care 2006;10:R121.
18. Inouye SK, van Dyke CH, Alessi CA, Balkin S, Siegal AP, Horwitz RI, Clarifying confusion: The confusion assessment method. Ann Intern Med 1990;113:941-8
19. Albert MS, Levkoff SE, Reilly C, Liptzin B, Pilgrim D, Cleary PD, et al. The Delirium Symptom Interview: An interview for the detection of delirium symptoms in hospitalized patients. J Geriatr Psychiatry Neurol 1992;5:14-21.
20. Breitbart W, Rosenfeld B, Roth A, Smith MJ, Cohen K, Passik S. The memorial delirium assessment scale. J Pain Symptom Manage 1997;13:128-37.
21. Trzepacz PT. The delirium rating scale. Its use in consultation-liaison research. Psychosomatics 1999;40:193-204.
22. Someya T, Endo T, Hara T, Yagi G, Suzuki J. A survey on the drug therapy for delirium. Psychiatry Clin Neurosci 2001;55:397-401.
23. Chuang YM, Liu CY, Lee SH, Huang YC, Yeh EK, Yang YY. Establishment and inter-rater operation reliability study of Chinese version of Delirium Rating Scale. Annual meeting of the Society of Psychiatrics. Taiwan; 1998.
24. Grassi L, Caraceni A, Beltrami E, Borreani C, Zamorani M, Maltoni M, et al. Assessing delirium in cancer patients: The Italian versions of the Delirium Rating Scale and the Memorial Delirium Assessment Scale. J Pain Symptom Manage 2001;21:59-68.
25. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th edn. Washington, DC: American Psychiatric Association 1994.
26. Morita T, Fujimoto K, Imura C, Nanba M, Fukumoto N, Itoh T. Self-reported practice, confidence, and knowledge about palliative care of nurses in a Japanese regional cancer center. Longitudinal study after 1-year activity of palliative care team. Am J Hosp Palliat Care 2006;23:385-91.
27. Spiller JA, Keen JC. Hypoactive delirium: Assessing the extent of problem for inpatient specialist palliative care. Palliat Med 2006;20:17-23.
28. O'Keeffe ST, Lavan JN. Clinical significance of delirium subtypes in older people. Age Ageing 1999; 28:115-9.
29. Marcantonio E, Ta T, Duthie E, Resnick NM. Delirium severity and psychomotor types: Their relationship with outcomes after hip fracture repair. J Am Geriatr Soc 2002;50:850-7.
30. Boyle DA. Delirium in older adults with cancer: Implications for practice and research: Oncol Nurs Forum 2006;33:61-78.
31. Morrison C. Identification and management of delirium in the critically ill patient with cancer. AACN Clin Issues 2003;14:92-111.
32. Lagman RL, Davis MP, LeGrand SB, Walsh D. Common symptoms in advanced cancer. Surg Clin North Am 2005;85:237-55.
33. Tsai JS, Wu CH, Chiu TY, Hu WY, Chen CY. Symptom patterns of advanced cancer patients in a palliative care unit. Palliat Med 2006;20:617-22.
34. Eden BM, Foreman MD. Problems associated with underrecognition of delirium in critical care: A case study. Heart Lung 1996;25:388-400.
35. Fann JR, Sullivan AK. Delirium in the course of cancer treatment, Semin Clin Neuropsychiatry 2003;8:217-28.
36. Toscani P., Brunelli C,. Miccinesi G, Costantini M, Gallucci M, Tamburini K et al. Predicting survival in terminal cancer patients: clinical observation or quality-of-life evaluation? Palliat Med 2005;19:220-7.
37. Breitbart W, Gibson C, Tremblay A. The delirium experience: Delirium recall and delirium-related distress in hospitalized patients with cancer, their spouses/caregivers, and their nurses. Psychosomatics 2002;43:183-94.
38. McNamara B. Good enough death: Autonomy and choice in Australian palliative care. Soc Sci Med 2004;58:929-38
39. Hirai K, Miyashita M, Morita T, Sanjo M, Uchitomi Y. Good death in Japanese cancer care: A qualitative study. J Pain Symptom Manage 2006;31:140-7
40. Bruera E, Neumann CM. Management of specific symptom complexes in patients receiving palliative care. CMAJ 1998;158:1717-26.
41. Tune L. The role of antipsychotics in treating delirium. Curr Psychiatry Rep 2002;4:209-12.
42. Volavka J, Czobor P, Sheitman B, Lindenmayer JP, Citrome L, McEvoy JP, et al. Clozapine, olanzapine, risperidone, and baloperidol in the treatment of patients with chronic schizophrenia and schizoaffectivc disorder. Am J Psychiatry 2002;159:255-62.
43. Boettger S, Breitbart W. Atypical antipsychotics in the management of delirium: A review of the empirical literature. Palliat Support Care 2005;3:227-37.
44. Schwartz TL, Magand PS. Treatment of delirium with quetiapine. Prim Care Companion J Clin Psychiatry 2000;2:10-2.
45. Sasaki Y, Matsuyama T, Inoue S, Sunami T, Inoue T, Denda Y, et al. A prospective, open-label, flexible-dose study of quetiapine in the treatment of delirium. J Clin Psychiatry 2003;11:1316-21.
46. Breitbart W, Tremblay A, Gibson C. An open trial of olanzapine for the treatment of delirium in hospitalized cancer patients. Psychosomatics 2002;43:175-82.
47. Morita T, Chinone Y, Ikenaga M, Miyoshi M, Nakaho T, Nishitateno K, et al. Ethical validity of palliative sedation therapy: A multicenter, prospective, observational study conducted on specialized palliative care units in Japan. J Pain Symptom Manage 2005;30:308-19.
48. Morita T, Chinone Y, Ikenaga M, Miyoshi M, Nakaho T, Nishitateno K, et al. Efficacy and safety of palliative sedation therapy: A multicenter, prospective, observational study conducted on specialized palliative care units in Japan. J Pain Symptom Manage 2005;30:320-8.
49. Moryl N, Kogan M, Comfort C, Obbens E. Methadone in the treatment of pain and terminal delirum in advanced cancer patients. Palliat Support Care 2005;3:311-7.
50. Ling J, Rees E, Hardy J. What influences participation in clinical trials in palliative care centre? Eur J Cancer 2000;36:621-6.
51. Hudson P, Aranda S, McMurray N. Randomized controlled trials in palliative care: Overcoming ihe obstacles. Int J Palliat Nurs 2001;7:427-34.
52. Fainsinger R, Miller MJ, Bruera E, Hanson J, Maceachern T. Symptom control during the last week of life on a palliative care unit. J Palliat Care 1991;7:5-11.
53. Uchitomi Y. Management of psychiatric symptoms in cancer patients (in Japanese). Gan To Kagaku Ryoho 2002;29:1305-10.
54. Brajtman S, Hiquchi K, McPherson C. Caring for patients with terminal delirium: Palliative care unit and home care nurses' experiences. Int J Palliat Nurs 2005;12:150-6.
55. Meijler WJ, Van Heest F, Otter R, Sleijifer DT. Educational needs of general practitioners in palliative care: Outcome of a focus group study. J Cancer Educ 2005;20:28-33
56. Kissane DW, Smith GC. Consultation-liaison psychiatry in an Australian oncology unit. Aust N Z J Psychiatry 1996;30:397-404.