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Volumn 158, Issue 3, 2008, Pages 578-586

Antitumour effects in mycosis fungoides of the immunomodulatory, tellurium-based compound, AS101

Author keywords

Apoptosis; AS101; Cutaneous T cell lymphoma; Reactive oxygen species

Indexed keywords

AMMONIUM TRICHLORO(DIOXYETHYLENE O,O')TELLURATE; CASPASE 3; CASPASE 9; MANGANESE SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE;

EID: 39049085272     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2007.08414.x     Document Type: Article
Times cited : (23)

References (43)
  • 1
    • 0036682407 scopus 로고    scopus 로고
    • Phase II trial of interferon-alpha-2a plus psolaren with ultraviolet light a in patients with cutaneous T-cell lymphoma
    • Chiarion-Sileni V, Bononi A, Fornasa CV et al. Phase II trial of interferon-alpha-2a plus psolaren with ultraviolet light A in patients with cutaneous T-cell lymphoma. Cancer 2002 95 : 569 75.
    • (2002) Cancer , vol.95 , pp. 569-75
    • Chiarion-Sileni, V.1    Bononi, A.2    Fornasa, C.V.3
  • 2
    • 0028274867 scopus 로고
    • Cytogenetic findings in cell lines from cutaneous T-cell lymphoma
    • Kaltoft K, Hansen BH, Thestrup-Pedersen K. Cytogenetic findings in cell lines from cutaneous T-cell lymphoma. Dermatol Clin 1994 12 : 295 304.
    • (1994) Dermatol Clin , vol.12 , pp. 295-304
    • Kaltoft, K.1    Hansen, B.H.2    Thestrup-Pedersen, K.3
  • 3
    • 4043114833 scopus 로고    scopus 로고
    • Establishment of a mouse xenograft model for mycosis fungoides
    • Thaler S, Burger AM, Schulz T et al. Establishment of a mouse xenograft model for mycosis fungoides. Exp Dermatol 2004 13 : 406 12.
    • (2004) Exp Dermatol , vol.13 , pp. 406-12
    • Thaler, S.1    Burger, A.M.2    Schulz, T.3
  • 4
    • 0346873026 scopus 로고    scopus 로고
    • MLV/HIV-pseudotyped vectors: A new treatment option for cutaneous T cell lymphomas
    • Thaler S, Burger AM, Schulz T et al. MLV/HIV-pseudotyped vectors: a new treatment option for cutaneous T cell lymphomas. Mol Ther 2003 8 : 756 61.
    • (2003) Mol Ther , vol.8 , pp. 756-61
    • Thaler, S.1    Burger, A.M.2    Schulz, T.3
  • 5
    • 0023629333 scopus 로고
    • A new immunomodulating compound (AS-101) with potential therapeutic application
    • Sredni B, Caspi RR, Klein A et al. A new immunomodulating compound (AS-101) with potential therapeutic application. Nature 1987 330 : 173 6.
    • (1987) Nature , vol.330 , pp. 173-6
    • Sredni, B.1    Caspi, R.R.2    Klein, A.3
  • 6
    • 0029760061 scopus 로고    scopus 로고
    • Predominance of TH1 response in tumor-bearing mice and cancer patients treated with AS101
    • Sredni B, Tichler T, Shani A et al. Predominance of TH1 response in tumor-bearing mice and cancer patients treated with AS101. J Natl Cancer Inst 1996 88 : 1276 84.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1276-84
    • Sredni, B.1    Tichler, T.2    Shani, A.3
  • 7
    • 0032193698 scopus 로고    scopus 로고
    • Up-regulation by ammonium trichloro (dioxoethylene-O,O') tellurate (AS101) of Fas/Apo-1 expression on B16 melanoma cells: Implications for the antitumor effects of AS101
    • Kalechman Y, Strassmann G, Albeck M et al. Up-regulation by ammonium trichloro (dioxoethylene-O,O') tellurate (AS101) of Fas/Apo-1 expression on B16 melanoma cells: implications for the antitumor effects of AS101. J Immunol 1998 161 : 3536 42.
    • (1998) J Immunol , vol.161 , pp. 3536-42
    • Kalechman, Y.1    Strassmann, G.2    Albeck, M.3
  • 8
    • 33750510701 scopus 로고    scopus 로고
    • The immunomodulator AS101 induces growth arrest and apoptosis in multiple myeloma: Association with the Akt/survivin pathway
    • Hayun M, Naor Y, Weil M et al. The immunomodulator AS101 induces growth arrest and apoptosis in multiple myeloma: association with the Akt/survivin pathway. Biochem Pharmacol 2006 72 : 1423 31.
    • (2006) Biochem Pharmacol , vol.72 , pp. 1423-31
    • Hayun, M.1    Naor, Y.2    Weil, M.3
  • 9
    • 0030070066 scopus 로고    scopus 로고
    • The protective role of the immunomodulator AS101 against chemotherapy-induced alopecia studies on human and animal models
    • Sredni B, Xu RH, Albeck M et al. The protective role of the immunomodulator AS101 against chemotherapy-induced alopecia studies on human and animal models. Int J Cancer 1996 65 : 97 103.
    • (1996) Int J Cancer , vol.65 , pp. 97-103
    • Sredni, B.1    Xu, R.H.2    Albeck, M.3
  • 10
    • 0034776322 scopus 로고    scopus 로고
    • Cytokine profile of patients with mycosis fungoides and the immunomodulatory effect of AS101
    • Shohat M, Hodak E, Sredni B et al. Cytokine profile of patients with mycosis fungoides and the immunomodulatory effect of AS101. Acta Derm Venereol (Stockh) 2001 81 : 255 7.
    • (2001) Acta Derm Venereol (Stockh) , vol.81 , pp. 255-7
    • Shohat, M.1    Hodak, E.2    Sredni, B.3
  • 11
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC et al. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1991 139 : 271 9.
    • (1991) J Immunol Methods , vol.139 , pp. 271-9
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3
  • 12
    • 0025806764 scopus 로고
    • Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1
    • Smiley ST, Reers M, Mottola-Hartshorn C et al. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci USA 1991 88 : 3671 5.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3671-5
    • Smiley, S.T.1    Reers, M.2    Mottola-Hartshorn, C.3
  • 13
    • 0018903124 scopus 로고
    • Mitogen requirements for the in vitro propagation of cutaneous T-cell lymphomas
    • Gazdar AF, Carney DN, Bunn PA et al. Mitogen requirements for the in vitro propagation of cutaneous T-cell lymphomas. Blood 1980 55 : 409 17.
    • (1980) Blood , vol.55 , pp. 409-17
    • Gazdar, A.F.1    Carney, D.N.2    Bunn, P.A.3
  • 14
    • 0026721931 scopus 로고
    • Establishment of two continuous T-cell strains from a single plaque of a patient with mycosis fungoides
    • Kaltoft K, Bisballe S, Dyrberg T et al. Establishment of two continuous T-cell strains from a single plaque of a patient with mycosis fungoides. In Vitro Cell Dev Biol 1992 28A : 161 7.
    • (1992) In Vitro Cell Dev Biol , vol.28 , pp. 161-7
    • Kaltoft, K.1    Bisballe, S.2    Dyrberg, T.3
  • 15
    • 2642689658 scopus 로고    scopus 로고
    • Proteases to die for
    • Cryns V, Yuan J. Proteases to die for. Genes Dev 1998 12 : 1551 70.
    • (1998) Genes Dev , vol.12 , pp. 1551-70
    • Cryns, V.1    Yuan, J.2
  • 16
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen GM. Caspases: the executioners of apoptosis. Biochem J 1997 326 : 1 16.
    • (1997) Biochem J , vol.326 , pp. 1-16
    • Cohen, G.M.1
  • 17
    • 0030865646 scopus 로고    scopus 로고
    • Dual regulation of caspase activity by hydrogen peroxide: Implications for apoptosis
    • Hampton MB, Orrenius S. Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis. FEBS Lett 1997 414 : 552 6.
    • (1997) FEBS Lett , vol.414 , pp. 552-6
    • Hampton, M.B.1    Orrenius, S.2
  • 18
    • 0033805296 scopus 로고    scopus 로고
    • Triggering and modulation of apoptosis by oxidative stress
    • Chandra J, Samali A, Orrenius S. Triggering and modulation of apoptosis by oxidative stress. Free Radic Biol Med 2000 29 : 323 33.
    • (2000) Free Radic Biol Med , vol.29 , pp. 323-33
    • Chandra, J.1    Samali, A.2    Orrenius, S.3
  • 19
    • 23844541335 scopus 로고    scopus 로고
    • Green tea component, catechin, induces apoptosis of human malignant B cells via production of reactive oxygen species
    • Nakazato T, Ito K, Ikeda Y et al. Green tea component, catechin, induces apoptosis of human malignant B cells via production of reactive oxygen species. Clin Cancer Res 2005 11 : 6040 9.
    • (2005) Clin Cancer Res , vol.11 , pp. 6040-9
    • Nakazato, T.1    Ito, K.2    Ikeda, Y.3
  • 20
    • 0034852801 scopus 로고    scopus 로고
    • Selenium and signal transduction: Roads to cell death and anti-tumour activity
    • Ghose A, Fleming J, Harrison PR. Selenium and signal transduction: roads to cell death and anti-tumour activity. Biofactors 2001 14 : 127 33.
    • (2001) Biofactors , vol.14 , pp. 127-33
    • Ghose, A.1    Fleming, J.2    Harrison, P.R.3
  • 21
    • 33947444549 scopus 로고
    • The chemistry and toxicity of selenium compounds, with special reference to the selenium problem
    • Painter EP. The chemistry and toxicity of selenium compounds, with special reference to the selenium problem. Chem Rev 1941 28 : 179 213.
    • (1941) Chem Rev , vol.28 , pp. 179-213
    • Painter, E.P.1
  • 22
    • 0031228020 scopus 로고    scopus 로고
    • Active oxygen generation as a possible mechanism of selenium toxicity
    • Seko Y, Imura N. Active oxygen generation as a possible mechanism of selenium toxicity. Biomed Environ Sci 1997 10 : 333 9.
    • (1997) Biomed Environ Sci , vol.10 , pp. 333-9
    • Seko, Y.1    Imura, N.2
  • 23
    • 0027500419 scopus 로고
    • Generation of reactive oxygen species from the reaction of selenium compounds with thiols and mammary tumor cells
    • Yan L, Spallholz JE. Generation of reactive oxygen species from the reaction of selenium compounds with thiols and mammary tumor cells. Biochem Pharmacol 1993 45 : 429 37.
    • (1993) Biochem Pharmacol , vol.45 , pp. 429-37
    • Yan, L.1    Spallholz, J.E.2
  • 24
    • 0028332519 scopus 로고
    • On the nature of selenium toxicity and carcinostatic activity
    • Spallholz JE. On the nature of selenium toxicity and carcinostatic activity. Free Radic Biol Med 1994 17 : 45 64.
    • (1994) Free Radic Biol Med , vol.17 , pp. 45-64
    • Spallholz, J.E.1
  • 25
    • 1442339222 scopus 로고    scopus 로고
    • Hair growth induction by the tellurium immunomodulator AS101: Association with delayed terminal differentiation of follicular keratinocytes and ras-dependent up-regulation of KGF expression
    • Sredni B, Gal R, Cohen IJ et al. Hair growth induction by the tellurium immunomodulator AS101: association with delayed terminal differentiation of follicular keratinocytes and ras-dependent up-regulation of KGF expression. FASEB J 2004 18 : 400 2.
    • (2004) FASEB J , vol.18 , pp. 400-2
    • Sredni, B.1    Gal, R.2    Cohen, I.J.3
  • 26
    • 0001378141 scopus 로고    scopus 로고
    • Tellurium compounds: Selective inhibition of cysteine proteases and model reaction with thiols
    • Albeck A, Weitman H, Sredni B, Albeck M. Tellurium compounds: selective inhibition of cysteine proteases and model reaction with thiols. Inorg Chem 1998 37 : 1704 12.
    • (1998) Inorg Chem , vol.37 , pp. 1704-12
    • Albeck, A.1    Weitman, H.2    Sredni, B.3    Albeck, M.4
  • 27
    • 34249823664 scopus 로고    scopus 로고
    • Multifunctional tellurium molecule protects and restores dopaminergic neurons in Parkinson's disease models
    • Sredni B, Geffen-Aricha R, Duan W et al. Multifunctional tellurium molecule protects and restores dopaminergic neurons in Parkinson's disease models. FASEB J 2007 21 : 1870 83.
    • (2007) FASEB J , vol.21 , pp. 1870-83
    • Sredni, B.1    Geffen-Aricha, R.2    Duan, W.3
  • 28
    • 34249779578 scopus 로고    scopus 로고
    • The organotellurium compound ammonium trichloro(dioxoethylene-O,O') tellurate reacts with homocysteine to form homocystine and decreases homocysteine levels in hyperhomocysteinemic mice
    • Okun E, Dikshtein Y, Carmely A et al. The organotellurium compound ammonium trichloro(dioxoethylene-O,O') tellurate reacts with homocysteine to form homocystine and decreases homocysteine levels in hyperhomocysteinemic mice. FEBS J 2007 274 : 3159 70.
    • (2007) FEBS J , vol.274 , pp. 3159-70
    • Okun, E.1    Dikshtein, Y.2    Carmely, A.3
  • 29
    • 34447647680 scopus 로고    scopus 로고
    • Neutral and positively charged thiols synergize the effect of the immunomodulator AS101 as a growth inhibitor of Jurkat cells, by increasing its uptake
    • Frei GM, Lebenthal I, Albeck M et al. Neutral and positively charged thiols synergize the effect of the immunomodulator AS101 as a growth inhibitor of Jurkat cells, by increasing its uptake. Biochem Pharmacol 2007 74 : 712 22.
    • (2007) Biochem Pharmacol , vol.74 , pp. 712-22
    • Frei, G.M.1    Lebenthal, I.2    Albeck, M.3
  • 30
    • 0034518556 scopus 로고    scopus 로고
    • Constitutive expression of NF-kappa B is a characteristic feature of mycosis fungoides: Implications for apoptosis resistance and pathogenesis
    • Izban KF, Ergin M, Qin JZ et al. Constitutive expression of NF-kappa B is a characteristic feature of mycosis fungoides: implications for apoptosis resistance and pathogenesis. Hum Pathol 2000 31 : 1482 90.
    • (2000) Hum Pathol , vol.31 , pp. 1482-90
    • Izban, K.F.1    Ergin, M.2    Qin, J.Z.3
  • 31
    • 0032577708 scopus 로고    scopus 로고
    • Constitutive activation of NF-kappaB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role of tumor necrosis factor and reactive oxygen intermediates
    • Giri DK, Aggarwal BB. Constitutive activation of NF-kappaB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role of tumor necrosis factor and reactive oxygen intermediates. J Biol Chem 1998 273 : 14008 14.
    • (1998) J Biol Chem , vol.273 , pp. 14008-14
    • Giri, D.K.1    Aggarwal, B.B.2
  • 32
    • 33644755512 scopus 로고    scopus 로고
    • Down-regulating constitutive activation of the NF-kappaB canonical pathway overcomes the resistance of cutaneous T-cell lymphoma to apoptosis
    • Sors A, Jean-Louis F, Pellet C et al. Down-regulating constitutive activation of the NF-kappaB canonical pathway overcomes the resistance of cutaneous T-cell lymphoma to apoptosis. Blood 2006 107 : 2354 63.
    • (2006) Blood , vol.107 , pp. 2354-63
    • Sors, A.1    Jean-Louis, F.2    Pellet, C.3
  • 33
    • 0029032154 scopus 로고
    • Low-level oxidative stress causes cell-cycle specific arrest in cultured cells
    • Clopton DA, Saltman P. Low-level oxidative stress causes cell-cycle specific arrest in cultured cells. Biochem Biophys Res Commun 1995 210 : 189 96.
    • (1995) Biochem Biophys Res Commun , vol.210 , pp. 189-96
    • Clopton, D.A.1    Saltman, P.2
  • 34
    • 0028345161 scopus 로고
    • Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells
    • Chen Q, Ames BN. Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. Proc Natl Acad Sci USA 1994 91 : 4130 4.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4130-4
    • Chen, Q.1    Ames, B.N.2
  • 35
  • 36
    • 20144387362 scopus 로고    scopus 로고
    • Immunopathogenesis and therapy of cutaneous T cell lymphoma
    • Kim EJ, Hess S, Richardson SK et al. Immunopathogenesis and therapy of cutaneous T cell lymphoma. J Clin Invest 2005 115 : 798 812.
    • (2005) J Clin Invest , vol.115 , pp. 798-812
    • Kim, E.J.1    Hess, S.2    Richardson, S.K.3
  • 37
    • 0026769328 scopus 로고
    • Aberrant cytokine production by Sézary syndrome patients: Cytokine secretion pattern resembles murine Th2 cells
    • Vowels BR, Cassin M, Vonderheid EC et al. Aberrant cytokine production by Sézary syndrome patients: cytokine secretion pattern resembles murine Th2 cells. J Invest Dermatol 1992 99 : 90 4.
    • (1992) J Invest Dermatol , vol.99 , pp. 90-4
    • Vowels, B.R.1    Cassin, M.2    Vonderheid, E.C.3
  • 38
    • 0028117885 scopus 로고
    • Th2 cytokine mRNA expression in skin in cutaneous T-cell lymphoma
    • Vowels BR, Lessin SR, Cassin M et al. Th2 cytokine mRNA expression in skin in cutaneous T-cell lymphoma. J Invest Dermatol 1994 103 : 669 73.
    • (1994) J Invest Dermatol , vol.103 , pp. 669-73
    • Vowels, B.R.1    Lessin, S.R.2    Cassin, M.3
  • 39
    • 0029912682 scopus 로고    scopus 로고
    • Progression of mycosis fungoides is associated with increasing cutaneous expression of interleukin-10 mRNA
    • Asadullah K, Docke WD, Haeussler A et al. Progression of mycosis fungoides is associated with increasing cutaneous expression of interleukin-10 mRNA. J Invest Dermatol 1996 107 : 833 7.
    • (1996) J Invest Dermatol , vol.107 , pp. 833-7
    • Asadullah, K.1    Docke, W.D.2    Haeussler, A.3
  • 40
    • 0028899589 scopus 로고
    • CD8-positive tumor-infiltrating lymphocytes influence the long-term survival of patients with mycosis fungoides
    • Hoppe RT, Medeiros LJ, Warnke RA et al. CD8-positive tumor-infiltrating lymphocytes influence the long-term survival of patients with mycosis fungoides. J Am Acad Dermatol 1995 32 : 448 53.
    • (1995) J Am Acad Dermatol , vol.32 , pp. 448-53
    • Hoppe, R.T.1    Medeiros, L.J.2    Warnke, R.A.3
  • 41
    • 0031569382 scopus 로고    scopus 로고
    • The immunomodulator AS-101 inhibits IL-10 release and augments TNF alpha and IL-1 alpha release by mouse and human mononuclear phagocytes
    • Strassmann G, Kambayashi T, Jacob CO et al. The immunomodulator AS-101 inhibits IL-10 release and augments TNF alpha and IL-1 alpha release by mouse and human mononuclear phagocytes. Cell Immunol 1997 176 : 180 5.
    • (1997) Cell Immunol , vol.176 , pp. 180-5
    • Strassmann, G.1    Kambayashi, T.2    Jacob, C.O.3
  • 42
    • 0028905535 scopus 로고
    • Role of endogenous cytokines secretion in radioprotection conferred by the immunomodulator ammonium trichloro (dioxyethylene-O-O') tellurate
    • Kalechman Y, Zuloff A, Albeck M et al. Role of endogenous cytokines secretion in radioprotection conferred by the immunomodulator ammonium trichloro (dioxyethylene-O-O') tellurate. Blood 1995 85 : 1555 61.
    • (1995) Blood , vol.85 , pp. 1555-61
    • Kalechman, Y.1    Zuloff, A.2    Albeck, M.3
  • 43
    • 0037373243 scopus 로고    scopus 로고
    • Production of the novel mesangial autocrine growth factors GDNF and IL-10 is regulated by the immunomodulator AS101
    • Kalechman Y, Sredni B, Weinstein T et al. Production of the novel mesangial autocrine growth factors GDNF and IL-10 is regulated by the immunomodulator AS101. J Am Soc Nephrol 2003 14 : 620 30.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 620-30
    • Kalechman, Y.1    Sredni, B.2    Weinstein, T.3


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