CXCR3 <-> ligand-mediated skin inflammation in cutaneous lichenoid graft-versus-host disease

Journal of the American Academy of Dermatology

Volumn 58, Issue 3, 2008, Pages 437-442

  Wenzel, Joerg ^a   Lucas, Svenja ^a   Zahn, Sabine ^a   Mikus, Sandra ^a   Metze, Dieter ^b   Ständer, Sonja ^b   von Stebut, Esther ^c   Hillen, Uwe ^d   Bieber, Thomas ^a   Tüting, Thomas ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

^d UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD20 ANTIBODY; CD3 ANTIGEN; CD4 ANTIGEN; CD68 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CXCR3; CXCL9 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; LIGAND; MESSENGER RNA;

ARTICLE; CYTOKINE RELEASE; GRAFT VERSUS HOST REACTION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LICHENOID ERUPTION; PRIORITY JOURNAL; PUNCH BIOPSY; SIGNAL TRANSDUCTION; SKIN BIOPSY; SKIN INFLAMMATION;

CHEMOKINE CXCL10; CHEMOKINE CXCL9; CHRONIC DISEASE; DERMATITIS; EPIDERMIS; GRAFT VS HOST DISEASE; GTP-BINDING PROTEINS; HUMANS; IN SITU HYBRIDIZATION; INTERFERON TYPE I; INTERFERON-ALPHA; LICHEN PLANUS; LICHENOID ERUPTIONS; LIGANDS; LYMPHOCYTES; RECEPTORS, CXCR3; RNA, MESSENGER; SKIN DISEASES; T-LYMPHOCYTES;

EID: 38949203028     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaad.2007.10.647     Document Type: Article

References (24)

1. Anderson B.E., McNiff J.M., Jain D., Blazar B.R., Shlomchik W.D., and Shlomchik M.J. Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: requirements depend on target organ. Blood 105 (2005) 2227-2234
2. Fimiani M., De Aloe G., and Cuccia A. Chronic graft versus host disease and skin. J Eur Acad Dermatol Venereol 17 (2003) 512-517
3. Wenzel J., Scheler M., Proelss J., Bieber T., and Tuting T. Type I interferon associated cytotoxic inflammation in lichen planus. J Cutan Pathol 33 (2006) 672-678
4. Wenzel J., Worenkamper E., Freutel S., Henze S., Haller O., Bieber T., et al. Enhanced type I interferon signalling promotes Th1-biased inflammation in cutaneous lupus erythematosus. J Pathol 205 (2005) 435-442
5. Wenzel J., Uerlich M., Worrenkamper E., Freutel S., Bieber T., and Tuting T. Scarring skin lesions of discoid lupus erythematosus are characterized by high numbers of skin-homing cytotoxic lymphocytes associated with strong expression of the type I interferon-induced protein MxA. Br J Dermatol 153 (2005) 1011-1015
6. Horisberger M.A. Interferon-induced human protein MxA is a GTPase which binds transiently to cellular proteins. J Virol 66 (1992) 4705-4709
7. Kotenko S.V., Gallagher G., Baurin V.V., Lewis-Antes A., Shen M., Shah N.K., et al. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Nat Immunol 4 (2003) 69-77
8. Haller O., and Kochs G. Interferon-induced mx proteins: dynamin-like GTPases with antiviral activity. Traffic 3 (2002) 710-717
9. Meller S., Winterberg F., Gilliet M., Müller A., Lauceviciute I., Rieker J., et al. Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: an amplification cycle triggering cutaneous lupus erythematosus. Arthritis Rheum 52 (2005) 1504-1516
10. Arpinati M., Chirumbolo G., Urbini B., Perrone G., Rondelli D., and Anasetti C. Role of plasmacytoid dendritic cells in immunity and tolerance after allogeneic hematopoietic stem cell transplantation. Transpl Immunol 11 (2003) 345-356
11. Wenzel J., Scheler M., Tuting T., and Bieber T. Evidence for a role of type I interferons in dermatomyositis. Br J Dermatol 153 (2005) 462-463
12. +-mediated inflammation and distinguishes this disease from atopic dermatitis and psoriasis. J Invest Dermatol 128 (2008) 67-78
13. Wenzel J., Scheler M., Proelss J., Bieber T., and Tuting T. Type I interferon-associated cytotoxic inflammation in lichen planus. J Cutan Pathol 33 (2006) 672-678
14. Klingemann H.G., Grigg A.P., Wilkie-Boyd K., Barnett M.J., Eaves A.C., Reece D.E., et al. Treatment with recombinant interferon (alpha-2b) early after bone marrow transplantation in patients at high risk for relapse. Blood 78 (1991) 3306-3311
15. Serrano J., Prieto E., Mazarbeitia F., Roman A., Llamas P., and Tomas J.F. Atypical chronic graft-versus-host disease following interferon therapy for chronic myeloid leukaemia relapsing after allogeneic BMT. Bone Marrow Transplant 27 (2001) 85-87
16. Dorr R.T. Interferon-alpha in malignant and viral diseases. A review. Drugs 45 (1993) 177-211
17. Lo Iacono O., Garcia-Monzon C., Almasio P., Garcia-Buey L., Craxi A., and Moreno-Otero R. Soluble adhesion molecules correlate with liver inflammation and fibrosis in chronic hepatitis C treated with interferon-alpha. Aliment Pharmacol Ther 12 (1998) 1091-1099
18. Ghayur T., Banerjee S., Hugunin M., Butler D., Herzog L., Carter A., et al. Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature 386 (1997) 619-623
19. Guillot B., Portales P., Du Thanh A., Merlet S., Dereure S., Clot J., et al. The expression of cytotoxic mediators is altered in mononuclear cells of patients with melanoma and increased by interferon-alpha treatment. Br J Dermatol 152 (2005) 690-696
20. Duffner U., Lu B., Hildebrandt G.C., Teshima T., Williams D.L., Reddy P., et al. Role of CXCR3-induced donor T-cell migration in acute GVHD. Exp Hematol 31 (2003) 897-902
21. Zhou L., Askew D., Wu C., and Gilliam A.C. Cutaneous gene expression by DNA microarray in murine sclerodermatous graft-versus-host disease, a model for human scleroderma. J Invest Dermatol 127 (2007) 281-292
22. Mapara M.Y., Leng C., Kim Y.M., Bronson R., Lokshin A., Luster A., et al. Expression of chemokines in GVHD target organs is influenced by conditioning and genetic factors and amplified by GVHR. Biol Blood Marrow Transplant 12 (2006) 623-634
23. Bovenschen H.J., Seyger M.M., and van de Kerkhof P.C. Plaque psoriasis vs. atopic dermatitis and lichen planus: a comparison for lesional T-cell subsets, epidermal proliferation and differentiation. Br J Dermatol 153 (2005) 72-78
24. Sugerman P.B., Satterwhite K., and Bigby M. Autocytotoxic T-cell clones in lichen planus. Br J Dermatol 142 (2000) 449-456