Synthesis of alkyl 6-methyl-4-(2-trifluoromethylphenyl)-1,2,3,4-tetrahydro- 2H-pyrimidine-2-one-5-carboxylates possessing a N-3 nitro substituent to determine calcium channel modulation structure-activity relationships

Journal of Heterocyclic Chemistry

Volumn 44, Issue 3, 2007, Pages 669-672

  Kaur, Kuljeet ^a   Knaus, Edward E ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

6 METHYL 3 NITRO 4 (2 TRIFLUOROMETHYLPHENYL) 1,2,3,4 TETRAHYDRO 2H PYRIMIDIN 2 ONE 5 CARBOXYLATE DERIVATIVE; 6 METHYL 4 (2 TRIFLUOROMETHYLPHENYL) 1,2,3,4 TETRAHYDRO 2H PYRIMIDIN 2 ONE 5 CARBOXYLATE DERIVATIVE; CALCIUM CHANNEL; CALCIUM CHANNEL AFFECTING AGENT; CALCIUM CHANNEL BLOCKING AGENT; NIFEDIPINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CATALYSIS; CHANNEL GATING; CONTROLLED STUDY; DRUG SYNTHESIS; GUINEA PIG; HEART LEFT ATRIUM; HEART MUSCLE CONTRACTILITY; IC 50; INOTROPISM; NONHUMAN; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

EID: 38949189413     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570440324     Document Type: Article

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