HA2-specific monoclonal antibodies as tools for differential recognition of influenza A virus antigenic subtypes

Virus Research

Volumn 132, Issue 1-2, 2008, Pages 181-186

  Varečková, Eva ^a   Mucha, Vojtech ^a   Kostolanský, František ^a   Gubareva, Larisa V ^b   Klimov, Alexander ^b  

^a INSTITUTE OF VIROLOGY   (Slovakia)

^b NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

Author keywords

Diagnostics; HA2 specific antibodies; Influenza; Intersubtype cross reactivity; Subtype signature motif

Indexed keywords

CROSS REACTING ANTIBODY; MONOCLONAL ANTIBODY;

ANTIGEN ANTIBODY REACTION; ANTIGEN RECOGNITION; ARTICLE; INFLUENZA VIRUS A; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; VIRUS DETECTION; VIRUS TYPING;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, VIRAL; ANTIBODY SPECIFICITY; ANTIGENS, VIRAL; BIRDS; DOGS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS; INFLUENZA IN BIRDS; INFLUENZA, HUMAN; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

EID: 38949184513     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virusres.2007.10.004     Document Type: Article

References (18)

1. Becht H., Huang R.T.C., Fleischer B., Boschek C.B., and Rott R. Immunogenic properties of the small chain of HA2 of the haemagglutinin of influenza viruses. J. Gen. Virol. 65 (1984) 173-183
2. Ey P.L., Prowse S.J., and Jenkin C.R. Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using Protein A-Sepharose. Biochemistry 15 (1978) 429-436
3. Gocník M., Fislová T., Sládková T., Mucha V., Kostolanský F., and Varečková E. Antibodies specific to the HA2 glycopolypeptide of influenza A virus haemagglutinin with fusion-inhibition activity contribute to the protection of mice against lethal infection. J. Gen. Virol. 88 (2007) 951-955
4. Graves P.N., Schulman J.L., Young J.F., and Palese P. Preparation of influenza virus subviral particles lacking the HA1 subunit of haemagglutinin: unmasking of cross-reactive HA2 determinants. Virology 126 (1983) 106-116
5. Ha Y., Stevens D.J., Skehel J.J., and Wiley D.C. H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes. EMBO J. 21 (2002) 865-875
6. Macken C., Lu H., Goodman J., and Boykin L. The value of a database in surveillance and vaccine selection. In: Osterhaus A.D.M.E., Cox N., and Hampson A.W. (Eds). Options for the Control of Influenza IV (2001), Elsevier Science, Amsterdam 103-106
7. Nobusawa E., Aoyama T., Kato H., Suzuki Y., Tateno Y., and Nakajima K. Comparison of complete amino acid sequences and receptor-binding properties among 13 serotypes of hemagglutinins of influenza A viruses. Virology 182 (1991) 475-485
8. Russ G., Poláková K., Kostolanský F., Styk B., and Vančíková M. Monoclonal antibodies to glycopolypeptides HA1 and HA2 of influenza virus hemagglutinin. Acta Virol. 31 (1987) 374-386
9. Sánchez-Fauquier A., Villanueva N., and Melero J.A. Isolation of cross-reactive, subtype-specific monoclonal antibodies against influenza virus HA1 and HA2 hemagglutinin subunits. Arch. Virol. 97 (1987) 251-265
10. Sánchez-Fauquier A., Gullien M., Martin J., Kendal A.P., and Melero J.A. Conservation of epitopes recognized by monoclonal antibodies against the separated subunits of influenza hemagglutinin among type A viruses of the same and different subtypes. Arch. Virol. 116 (1991) 1-4
11. Skehel J., and Wiley J.D.C. Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin. Annu. Rev. Biochem. 69 (2000) 531-569
12. Tkáčová M., Varečková E., Baker I.C., Love J.M., and Ziegler T. Evaluation of monoclonal antibodies for subtyping of currently circulating human type A influenza viruses. J. Clin. Microbiol. 35 (1997) 1196-1198
13. Varečková E., Betáková T., Mucha V., Soláriková L., Kostolanský F., Waris M., and Russ G. Preparation of monoclonal antibodies for the diagnosis of influenza A infection using different immunisation protocols. J. Immunol. Methods 180 (1995) 107-116
14. Varečková E., Cox N., and Klimov A. Evaluation of the subtype specificity of monoclonal antibodies raised against H1 and H3 subtypes of human influenza A virus hemagglutinins. J. Clin. Microbiol. 40 (2002) 2220-2223
15. Varečková E., Mucha V., Wharton S.A., and Kostolanský F. Inhibition of fusion activity of influenza A haemagglutinin mediated by HA2-specific monoclonal antibodies. Arch. Virol. 148 (2003) 469-486
16. Varečková E., Wharton S., Mucha V., Gocník M., and Kostolanský F. A monoclonal antibody specific to the HA2 glycoprotein of influenza A virus haemagglutinin that inhibits its fusion activity reduces replication of the virus. Acta Virol. 47 (2003) 229-236
17. Walls H.H., Harmon M.W., Slagle J.J., Stocksdale C., and Kendal A.P. Characterization and evaluation of monoclonal antibodies developed for typing influenza A and influenza B viruses. J. Clin. Microbiol. 23 (1986) 240-245
18. Ziegler T., Hall H., Sánchez-Fauquier A., Gamble W.C., and Cox N.J. Type- and subtype-specific detection of influenza viruses in clinical specimens by rapid culture assay. J. Clin. Microbiol. 33 (1995) 318-321