메뉴 건너뛰기




Volumn 20, Issue 6, 2007, Pages 465-469

A cell-based high-throughput screening assay for farnesoid X receptor agonists

Author keywords

Agonist; Chimera; Farnesoid X receptor; High throughput screening

Indexed keywords

ANTILIPEMIC AGENT; CELL RECEPTOR; COMPLEMENTARY DNA; DNA BINDING PROTEIN; FARNESOID X RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR; PRIMER DNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 38949174197     PISSN: 08953988     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (7)

References (11)
  • 1
    • 6344243614 scopus 로고    scopus 로고
    • The Farnesoid X Receptor (FXR) as modulator of bile acid metabolism
    • Kuipers F, Claudel T, Sturm E, et al. (2004). The Farnesoid X Receptor (FXR) as modulator of bile acid metabolism. Rev Endocr Metab Disord 5, 319-326.
    • (2004) Rev Endocr Metab Disord , vol.5 , pp. 319-326
    • Kuipers, F.1    Claudel, T.2    Sturm, E.3
  • 2
    • 0034537181 scopus 로고    scopus 로고
    • FXR, a Bile Acid Receptor and Biological Sensor
    • Tu H, Okamoto A Y, Shan B (2000). FXR, a Bile Acid Receptor and Biological Sensor. TCM 10, 30-35.
    • (2000) TCM , vol.10 , pp. 30-35
    • Tu, H.1    Okamoto, A.Y.2    Shan, B.3
  • 3
    • 0037462815 scopus 로고    scopus 로고
    • The farnesoid X-receptor is an essential regulator of cholesterol homeostasis
    • Lambert G, Amar M J, Guo G, et al. (2003). The farnesoid X-receptor is an essential regulator of cholesterol homeostasis. J Biol Chem 278, 2563-2570.
    • (2003) J Biol Chem , vol.278 , pp. 2563-2570
    • Lambert, G.1    Amar, M.J.2    Guo, G.3
  • 4
    • 22944467490 scopus 로고    scopus 로고
    • FXR, a therapeutic target for bile acid and lipid disorders
    • Westin S, Heyman R A, Martion R (2005). FXR, a therapeutic target for bile acid and lipid disorders. Mini Rev Med Chem 5, 719-727.
    • (2005) Mini Rev Med Chem , vol.5 , pp. 719-727
    • Westin, S.1    Heyman, R.A.2    Martion, R.3
  • 5
    • 10444281509 scopus 로고    scopus 로고
    • FXR as a novel therapeutic target for vascular disease
    • Boshop-Bailey D (2004). FXR as a novel therapeutic target for vascular disease. Drug News Perspect 17, 499-504.
    • (2004) Drug News Perspect , vol.17 , pp. 499-504
    • Boshop-Bailey, D.1
  • 6
    • 19044393451 scopus 로고    scopus 로고
    • Farnesoid X receptor agonism-a new approach to the treatment of cholesterol gallstone disease
    • Doggrell S A (2005). Farnesoid X receptor agonism-a new approach to the treatment of cholesterol gallstone disease. Expert Opin Investig Drugs 14, 535-538.
    • (2005) Expert Opin Investig Drugs , vol.14 , pp. 535-538
    • Doggrell, S.A.1
  • 7
    • 17444390461 scopus 로고    scopus 로고
    • A nuclear receptor ligand down-regulates cytosolic phospholipase A2 expression to reduce bile acid-induced cyclooxygenase 2 activity in cholangiocytes: Implications of anticarcinogenic action of farnesoid X receptor agonists
    • Komichi D, Tazuma S, Nishioka T, et al. (2005). A nuclear receptor ligand down-regulates cytosolic phospholipase A2 expression to reduce bile acid-induced cyclooxygenase 2 activity in cholangiocytes: implications of anticarcinogenic action of farnesoid X receptor agonists. Dig Dis Sei 50, 514-524.
    • (2005) Dig Dis Sei , vol.50 , pp. 514-524
    • Komichi, D.1    Tazuma, S.2    Nishioka, T.3
  • 8
    • 14544270531 scopus 로고    scopus 로고
    • Potential regulatory role of the farnesoid X receptor in the metabolic syndrome
    • Duran-Sandoval D, Cariou B, Fruchart J C, et al. (2005). Potential regulatory role of the farnesoid X receptor in the metabolic syndrome. Biochimie 87, 93-98.
    • (2005) Biochimie , vol.87 , pp. 93-98
    • Duran-Sandoval, D.1    Cariou, B.2    Fruchart, J.C.3
  • 9
    • 4043145033 scopus 로고    scopus 로고
    • Isohumulones, Bitter Acids Derived from Hops, Activate Both Peroxisome Proliferator-activated Receptor a and y Reduce Insulin Resistance
    • Yajima H, Ikeshima E, Shiraki, M (2004). Isohumulones, Bitter Acids Derived from Hops, Activate Both Peroxisome Proliferator-activated Receptor a and y Reduce Insulin Resistance. J Biol Chem 279, 33456-33462.
    • (2004) J Biol Chem , vol.279 , pp. 33456-33462
    • Yajima, H.1    Ikeshima, E.2    Shiraki, M.3
  • 10
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome roliferators-activated receptor gamma (PPAR gamma)
    • Lehmann J M, Moore L B, Smith-Oliver T A, et al. (1995). An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome roliferators-activated receptor gamma (PPAR gamma). J Biol Chem 270, 12953-12956.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3
  • 11
    • 0033003760 scopus 로고    scopus 로고
    • A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays
    • Zhang J H, Chung T D, Oldenburg K R (1999). A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. J Biomol Screen 4, 67-73.
    • (1999) J Biomol Screen , vol.4 , pp. 67-73
    • Zhang, J.H.1    Chung, T.D.2    Oldenburg, K.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.