Synthesis of alkyl 6-methyl-4-(2-pyridyl)-1,2,3,4-tetrahydro-2H-pyrimidine- 2-one-5-carboxylates for evaluation as calcium channel antagonists

Journal of Heterocyclic Chemistry

Volumn 44, Issue 3, 2007, Pages 745-747

  Kaur, Kuljeet ^a   Knaus, Edward E ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 PYRIDYLCARBOXALDEHYDE; 6 METHYL 4 (2 PYRIDYL) 1,2,3,4 TETRAHYDRO 2H PYRIMIDIN 2 ONE 5 CARBOXYLATE DERIVATIVE; ACETOACETIC ACID; ALDEHYDE; ALKYL GROUP; CALCIUM CHANNEL BLOCKING AGENT; CARBOXYL GROUP; CARBOXYLIC ACID DERIVATIVE; ETHYL 6 METHYL 4 (2 PYRIDYL) 1,2,3,4 TETRAHYDRO (2H) PYRIMIDIN 2 ONE 5 CARBOXYLATE; METHYL GROUP; NIFEDIPINE; PROPANE; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; TERT BUTYL GROUP; UNCLASSIFIED DRUG; UREA;

ANIMAL TISSUE; ARTICLE; BIGINELLI REACTION; BIOISOSTERISM; CATALYSIS; CHEMICAL MODIFICATION; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GUINEA PIG; HEART ATRIUM CONTRACTILITY; HEART LEFT ATRIUM; IC 50; ILEUM; INOTROPISM; NONHUMAN; POLYMERIZATION; SMOOTH MUSCLE; SUBSTITUTION REACTION;

EID: 38949170766     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570440339     Document Type: Article

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