A novel sesquiterpenoid dimer parviflorene F induces apoptosis by up-regulating the expression of TRAIL-R2 and a caspase-dependent mechanism

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 4, 2008, Pages 1756-1763

  Ohtsuki, Takashi ^a   Tamaki, Mayu ^a   Toume, Kazuhumi ^a   Ishibashi, Masami ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

Apoptosis; Caspase; Sesquiterpenoid dimer; TRAIL R2

Indexed keywords

CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; DEATH RECEPTOR 5; DNA; HYBRID PROTEIN; LIPOCORTIN 5; MESSENGER RNA; PARVIFLORENE F; SESQUITERPENOID; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME MECHANISM; HELA CELL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; STAINING; UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZ(A)ANTHRACENES; CASPASES; CELL LINE, TUMOR; CURCUMA; DIMERIZATION; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; SESQUITERPENES; UP-REGULATION;

CURCUMA PARVIFLORA;

EID: 38949133427     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.11.022     Document Type: Article

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