Detection of R337H, a germline TP53 mutation predisposing to multiple cancers, in asymptomatic women participating in a breast cancer screening program in Southern Brazil

Cancer Letters

Volumn 261, Issue 1, 2008, Pages 21-25

  Palmero, Edenir Inêz ^a,b   Schüler Faccini, Lavínia ^a,b   Caleffi, Maira ^c   Achatz, Maria Isabel Waddington ^d   Olivier, Magali ^e   Martel Planche, Ghyslaine ^e   Marcel, Virginie ^e   Aguiar, Ernestina ^a,b   Giacomazzi, Juliana ^a,b   Ewald, Ingrid Petroni ^a,b   Giugliani, Roberto ^a,b   Hainaut, Pierre ^e   Ashton Prolla, Patricia ^a,b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^c HOSPITAL MOINHOS DE VENTO   (Brazil)

^d A C CAMARGO CANCER CENTER   (Brazil)

^e INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

Author keywords

Breast cancer predisposition; Inherited breast cancer; Li Fraumeni syndrome; TP53 mutations

Indexed keywords

PROTEIN P53;

ADULT; AGED; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BRAZIL; BREAST CANCER; CANCER RISK; CANCER SCREENING; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DNA EXTRACTION; FAMILIAL CANCER; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; GERM LINE; HUMAN; MAMMOGRAPHY; NEOPLASM; PREVALENCE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; WOMEN'S HEALTH;

ADULT; AGED; BRAZIL; BREAST NEOPLASMS; FEMALE; GENES, P53; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GERM-LINE MUTATION; HUMANS; LI-FRAUMENI SYNDROME; MIDDLE AGED; NEOPLASMS; PEDIGREE;

EID: 38949125411     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2007.10.044     Document Type: Article

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