Gα-subunits differentially alter the conformation and agonist affinity of κ-opioid receptors

Biochemistry

Volumn 47, Issue 6, 2008, Pages 1567-1578

  Yan, Feng ^a   Mosier, Philip D ^c   Westkaemper, Richard B ^c   Roth, Bryan L ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION; LIGANDS;

CONFORMATIONAL CHANGES; EXTRACELLULAR PORTION; OPIOID RECEPTOR;

PROTEIN FOLDING;

GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; KAPPA OPIATE RECEPTOR;

AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG POTENTIATION; GENETICS; RADIOASSAY; SITE DIRECTED MUTAGENESIS;

CELL LINE; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; RADIOLIGAND ASSAY; RECEPTORS, OPIOID, KAPPA;

EID: 38949112855     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi701476b     Document Type: Article

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